ID   Y5847_STRAW             Reviewed;         561 AA.
AC   Q82B58;
DT   21-DEC-2004, integrated into UniProtKB/Swiss-Prot.
DT   01-JUN-2003, sequence version 1.
DT   03-AUG-2022, entry version 115.
DE   RecName: Full=Putative ABC transporter ATP-binding protein SAV_5847;
DE            EC=7.-.-.-;
GN   OrderedLocusNames=SAV_5847;
OS   Streptomyces avermitilis (strain ATCC 31267 / DSM 46492 / JCM 5070 / NBRC
OS   14893 / NCIMB 12804 / NRRL 8165 / MA-4680).
OC   Bacteria; Actinobacteria; Streptomycetales; Streptomycetaceae;
OC   Streptomyces.
OX   NCBI_TaxID=227882;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 31267 / DSM 46492 / JCM 5070 / NBRC 14893 / NCIMB 12804 / NRRL
RC   8165 / MA-4680;
RX   PubMed=11572948; DOI=10.1073/pnas.211433198;
RA   Omura S., Ikeda H., Ishikawa J., Hanamoto A., Takahashi C., Shinose M.,
RA   Takahashi Y., Horikawa H., Nakazawa H., Osonoe T., Kikuchi H., Shiba T.,
RA   Sakaki Y., Hattori M.;
RT   "Genome sequence of an industrial microorganism Streptomyces avermitilis:
RT   deducing the ability of producing secondary metabolites.";
RL   Proc. Natl. Acad. Sci. U.S.A. 98:12215-12220(2001).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 31267 / DSM 46492 / JCM 5070 / NBRC 14893 / NCIMB 12804 / NRRL
RC   8165 / MA-4680;
RX   PubMed=12692562; DOI=10.1038/nbt820;
RA   Ikeda H., Ishikawa J., Hanamoto A., Shinose M., Kikuchi H., Shiba T.,
RA   Sakaki Y., Hattori M., Omura S.;
RT   "Complete genome sequence and comparative analysis of the industrial
RT   microorganism Streptomyces avermitilis.";
RL   Nat. Biotechnol. 21:526-531(2003).
CC   -!- FUNCTION: Probably part of an ABC transporter complex. Responsible for
CC       energy coupling to the transport system (By similarity). {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000250}; Peripheral membrane
CC       protein {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the ABC transporter superfamily. {ECO:0000305}.
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DR   EMBL; BA000030; BAC73559.1; -; Genomic_DNA.
DR   RefSeq; WP_010987249.1; NZ_BAVY01000014.1.
DR   AlphaFoldDB; Q82B58; -.
DR   SMR; Q82B58; -.
DR   STRING; 227882.SAV_5847; -.
DR   EnsemblBacteria; BAC73559; BAC73559; SAVERM_5847.
DR   KEGG; sma:SAVERM_5847; -.
DR   eggNOG; COG3845; Bacteria.
DR   HOGENOM; CLU_000604_86_7_11; -.
DR   OMA; LAYGMEQ; -.
DR   OrthoDB; 870493at2; -.
DR   Proteomes; UP000000428; Chromosome.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0055085; P:transmembrane transport; IEA:InterPro.
DR   CDD; cd03225; ABC_cobalt_CbiO_domain1; 1.
DR   Gene3D; 3.40.50.300; -; 2.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR003439; ABC_transporter-like_ATP-bd.
DR   InterPro; IPR017871; ABC_transporter-like_CS.
DR   InterPro; IPR015856; ABC_transpr_CbiO/EcfA_su.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   Pfam; PF00005; ABC_tran; 2.
DR   SMART; SM00382; AAA; 2.
DR   SUPFAM; SSF52540; SSF52540; 2.
DR   PROSITE; PS00211; ABC_TRANSPORTER_1; 1.
DR   PROSITE; PS50893; ABC_TRANSPORTER_2; 2.
PE   3: Inferred from homology;
KW   ATP-binding; Cell membrane; Membrane; Nucleotide-binding;
KW   Reference proteome; Repeat; Translocase; Transport.
FT   CHAIN           1..561
FT                   /note="Putative ABC transporter ATP-binding protein
FT                   SAV_5847"
FT                   /id="PRO_0000092091"
FT   DOMAIN          2..243
FT                   /note="ABC transporter 1"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00434"
FT   DOMAIN          315..543
FT                   /note="ABC transporter 2"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00434"
FT   REGION          268..299
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        274..288
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   BINDING         36..43
FT                   /ligand="ATP"
FT                   /ligand_id="ChEBI:CHEBI:30616"
FT                   /ligand_label="1"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00434"
FT   BINDING         347..354
FT                   /ligand="ATP"
FT                   /ligand_id="ChEBI:CHEBI:30616"
FT                   /ligand_label="2"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00434"
SQ   SEQUENCE   561 AA;  58593 MW;  80DD17E3D4D10A06 CRC64;
     MIRFEDVSVT YDGAAEPTVR GVDFTVPEGE LVLLVGPSGV GKSTVLGAVS GLVPHFTGGT
     LRGRVTVAGR DTRTHKPREL ADVVGTVGQD PLSHFVTDTV EDELAYGMES LGIAPDVMRR
     RVEETLDLLG LAELRDRPIS TLSGGQQQRV AIGSVLTPHP KVLVLDEPTS ALDPAAAEEV
     LAVLQRLVHD LGTTVLMAEH RLERVVQYAD RVALLPAPGA PLTLGTPPEV MAASPVYPPV
     VDLGRLAGWS PLPLTVRDAR RRAGALRERL AATETPTPTA TATATAAPAP SPSRPRRPRL
     LRKRAPVPSA ALPVAAVEAL AVRRGRVEAL RRVDLTASPG EIIALMGRNG AGKSTLLGAL
     VGLVPPAGGS VRVGGAVPHR TAPRDLVRRV GLVPQEPRDL LYADTVAAEC VAADGDAGAE
     PGTCRALVSE LLPGVADGTH PRDLSEGQRL ALALAVVLTA RPPLLLLDEP TRGLDYAAKG
     RLVTLLRALA ADGHAIVLAT HDVELAAELA HRVVILAAGE VVADGPTAEV VVASPSFAPQ
     VTKILAPQHW LTVTQVREAL A