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Y5851_ARATH
ID   Y5851_ARATH             Reviewed;         224 AA.
AC   Q9LV63;
DT   08-MAR-2011, integrated into UniProtKB/Swiss-Prot.
DT   01-OCT-2000, sequence version 1.
DT   03-AUG-2022, entry version 118.
DE   RecName: Full=BTB/POZ domain-containing protein At5g48510;
GN   OrderedLocusNames=At5g48510; ORFNames=MJE7.15;
OS   Arabidopsis thaliana (Mouse-ear cress).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX   NCBI_TaxID=3702;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Columbia;
RX   PubMed=10718197; DOI=10.1093/dnares/7.1.31;
RA   Sato S., Nakamura Y., Kaneko T., Katoh T., Asamizu E., Kotani H.,
RA   Tabata S.;
RT   "Structural analysis of Arabidopsis thaliana chromosome 5. X. Sequence
RT   features of the regions of 3,076,755 bp covered by sixty P1 and TAC
RT   clones.";
RL   DNA Res. 7:31-63(2000).
RN   [2]
RP   GENOME REANNOTATION.
RC   STRAIN=cv. Columbia;
RX   PubMed=27862469; DOI=10.1111/tpj.13415;
RA   Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA   Town C.D.;
RT   "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT   genome.";
RL   Plant J. 89:789-804(2017).
RN   [3]
RP   DOMAIN BTB.
RX   PubMed=15749712; DOI=10.1074/jbc.m413247200;
RA   Gingerich D.J., Gagne J.M., Salter D.W., Hellmann H., Estelle M., Ma L.,
RA   Vierstra R.D.;
RT   "Cullins 3a and 3b assemble with members of the broad
RT   complex/tramtrack/bric-a-brac (BTB) protein family to form essential
RT   ubiquitin-protein ligases (E3s) in Arabidopsis.";
RL   J. Biol. Chem. 280:18810-18821(2005).
RN   [4]
RP   INTERACTION WITH CUL3A.
RX   PubMed=15772280; DOI=10.1105/tpc.105.031989;
RA   Figueroa P., Gusmaroli G., Serino G., Habashi J., Ma L., Shen Y., Feng S.,
RA   Bostick M., Callis J., Hellmann H., Deng X.W.;
RT   "Arabidopsis has two redundant Cullin3 proteins that are essential for
RT   embryo development and that interact with RBX1 and BTB proteins to form
RT   multisubunit E3 ubiquitin ligase complexes in vivo.";
RL   Plant Cell 17:1180-1195(2005).
CC   -!- FUNCTION: May act as a substrate-specific adapter of an E3 ubiquitin-
CC       protein ligase complex (CUL3-RBX1-BTB) which mediates the
CC       ubiquitination and subsequent proteasomal degradation of target
CC       proteins.
CC   -!- PATHWAY: Protein modification; protein ubiquitination.
CC   -!- SUBUNIT: Interacts with CUL3A. {ECO:0000269|PubMed:15772280}.
CC   -!- DOMAIN: The BTB/POZ-like domain may mediate the interaction with some
CC       component of ubiquitin ligase complexes. {ECO:0000269|PubMed:15749712}.
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DR   EMBL; AB020745; BAA96971.1; -; Genomic_DNA.
DR   EMBL; CP002688; AED95679.1; -; Genomic_DNA.
DR   RefSeq; NP_199662.1; NM_124227.2.
DR   AlphaFoldDB; Q9LV63; -.
DR   SMR; Q9LV63; -.
DR   BioGRID; 20153; 6.
DR   IntAct; Q9LV63; 6.
DR   STRING; 3702.AT5G48510.1; -.
DR   PaxDb; Q9LV63; -.
DR   PRIDE; Q9LV63; -.
DR   EnsemblPlants; AT5G48510.1; AT5G48510.1; AT5G48510.
DR   GeneID; 834907; -.
DR   Gramene; AT5G48510.1; AT5G48510.1; AT5G48510.
DR   KEGG; ath:AT5G48510; -.
DR   Araport; AT5G48510; -.
DR   TAIR; locus:2166066; AT5G48510.
DR   eggNOG; KOG1987; Eukaryota.
DR   HOGENOM; CLU_004253_9_1_1; -.
DR   InParanoid; Q9LV63; -.
DR   OMA; CIRMNIA; -.
DR   OrthoDB; 1379295at2759; -.
DR   PhylomeDB; Q9LV63; -.
DR   UniPathway; UPA00143; -.
DR   PRO; PR:Q9LV63; -.
DR   Proteomes; UP000006548; Chromosome 5.
DR   ExpressionAtlas; Q9LV63; baseline and differential.
DR   GO; GO:0016567; P:protein ubiquitination; IEA:UniProtKB-UniPathway.
DR   Gene3D; 3.30.710.10; -; 1.
DR   InterPro; IPR044784; At1g01640-like.
DR   InterPro; IPR000210; BTB/POZ_dom.
DR   InterPro; IPR011333; SKP1/BTB/POZ_sf.
DR   PANTHER; PTHR47274; PTHR47274; 1.
DR   Pfam; PF00651; BTB; 1.
DR   SMART; SM00225; BTB; 1.
DR   SUPFAM; SSF54695; SSF54695; 1.
DR   PROSITE; PS50097; BTB; 1.
PE   1: Evidence at protein level;
KW   Reference proteome; Ubl conjugation pathway.
FT   CHAIN           1..224
FT                   /note="BTB/POZ domain-containing protein At5g48510"
FT                   /id="PRO_0000406003"
FT   DOMAIN          24..98
FT                   /note="BTB"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00037"
SQ   SEQUENCE   224 AA;  24997 MW;  48EF185120B26D29 CRC64;
     MATPTNKEHF SGGLAKVLAE KWQVDVMLKA KNSDEGSAIS AHKLILASRS EVFKNMFELD
     EFKTSTKHVE TITLSEMKHE ELEAFVEFIC SDGSMLSANV KQHARSLYLA ADKYEILHLR
     DLCRTELISS LSLLNSLDLL VLAQIPFDKV LNDESFSYIK NNISTIASSD EFKLFVAGNP
     NLAVEIMKVS LITLTLRCSS CGSNHSLQGM YCCNCCRYGT LRLI
 
 
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