ID   Y585_HAEIN              Reviewed;         279 AA.
AC   P44018;
DT   01-NOV-1995, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1995, sequence version 1.
DT   25-MAY-2022, entry version 107.
DE   RecName: Full=Putative uncharacterized transporter HI_0585;
GN   OrderedLocusNames=HI_0585;
OS   Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Pasteurellales;
OC   Pasteurellaceae; Haemophilus.
OX   NCBI_TaxID=71421;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 51907 / DSM 11121 / KW20 / Rd;
RX   PubMed=7542800; DOI=10.1126/science.7542800;
RA   Fleischmann R.D., Adams M.D., White O., Clayton R.A., Kirkness E.F.,
RA   Kerlavage A.R., Bult C.J., Tomb J.-F., Dougherty B.A., Merrick J.M.,
RA   McKenney K., Sutton G.G., FitzHugh W., Fields C.A., Gocayne J.D.,
RA   Scott J.D., Shirley R., Liu L.-I., Glodek A., Kelley J.M., Weidman J.F.,
RA   Phillips C.A., Spriggs T., Hedblom E., Cotton M.D., Utterback T.R.,
RA   Hanna M.C., Nguyen D.T., Saudek D.M., Brandon R.C., Fine L.D.,
RA   Fritchman J.L., Fuhrmann J.L., Geoghagen N.S.M., Gnehm C.L., McDonald L.A.,
RA   Small K.V., Fraser C.M., Smith H.O., Venter J.C.;
RT   "Whole-genome random sequencing and assembly of Haemophilus influenzae
RT   Rd.";
RL   Science 269:496-512(1995).
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Multi-pass membrane
CC       protein {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the DcuC/DcuD transporter (TC 2.A.61) family.
CC       {ECO:0000305}.
CC   -!- CAUTION: Could be the product of a pseudogene. {ECO:0000305}.
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DR   EMBL; L42023; AAC22249.1; -; Genomic_DNA.
DR   PIR; I64009; I64009.
DR   AlphaFoldDB; P44018; -.
DR   STRING; 71421.HI_0585; -.
DR   TCDB; 2.A.61.1.3; the c4-dicarboxylate uptake c (dcuc) family.
DR   EnsemblBacteria; AAC22249; AAC22249; HI_0585.
DR   KEGG; hin:HI_0585; -.
DR   eggNOG; COG3069; Bacteria.
DR   HOGENOM; CLU_030262_1_0_6; -.
DR   OMA; LSHAPYN; -.
DR   PhylomeDB; P44018; -.
DR   Proteomes; UP000000579; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0015556; F:C4-dicarboxylate transmembrane transporter activity; IEA:InterPro.
DR   GO; GO:0015740; P:C4-dicarboxylate transport; IBA:GO_Central.
DR   InterPro; IPR004669; C4_dicarb_anaerob_car.
DR   InterPro; IPR018385; C4_dicarb_anaerob_car-like.
DR   PANTHER; PTHR42002; PTHR42002; 1.
DR   Pfam; PF03606; DcuC; 1.
DR   TIGRFAMs; TIGR00771; DcuC; 1.
PE   5: Uncertain;
KW   Cell membrane; Membrane; Reference proteome; Transmembrane;
KW   Transmembrane helix; Transport.
FT   CHAIN           1..279
FT                   /note="Putative uncharacterized transporter HI_0585"
FT                   /id="PRO_0000201633"
FT   TRANSMEM        29..49
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        77..97
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        105..125
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        147..167
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        186..206
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        240..260
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   279 AA;  28990 MW;  A724FFBD152476A9 CRC64;
     MMSPGSSHSA MISEMSGLTI TQVNLSHAPY NMIAGAIGAV VLTILALVFK DYGEQHRQAY
     LAEQKESEIK VIEGVNVLYA LAPLIPLVIL VIGGTSLQQV PGLEWTKMGV PQAMLIGAIY
     GIIVTRISPV KITEEFFNGM GNSYANVLGI IIAASVFVAG LKSTGAVDAA ISFLKESNEF
     VRWGATIGPF LMGLITGSGD AAAIAFNTAV TPHAVELGYT HVNLGMAAAI AGAIGRTASP
     IAGVTIVCAG LAMVSPVEMV KRTAPGMILA VLFLALFML