ID   Y588_BUCAI              Reviewed;         410 AA.
AC   P57648;
DT   01-JUN-2001, integrated into UniProtKB/Swiss-Prot.
DT   01-MAR-2001, sequence version 1.
DT   03-AUG-2022, entry version 101.
DE   RecName: Full=Uncharacterized transporter BU588;
GN   OrderedLocusNames=BU588;
OS   Buchnera aphidicola subsp. Acyrthosiphon pisum (strain APS) (Acyrthosiphon
OS   pisum symbiotic bacterium).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Erwiniaceae; Buchnera.
OX   NCBI_TaxID=107806;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=APS;
RX   PubMed=10993077; DOI=10.1038/35024074;
RA   Shigenobu S., Watanabe H., Hattori M., Sakaki Y., Ishikawa H.;
RT   "Genome sequence of the endocellular bacterial symbiont of aphids Buchnera
RT   sp. APS.";
RL   Nature 407:81-86(2000).
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Multi-pass membrane
CC       protein {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the major facilitator superfamily.
CC       {ECO:0000305}.
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DR   EMBL; BA000003; BAB13277.1; -; Genomic_DNA.
DR   RefSeq; NP_240391.1; NC_002528.1.
DR   RefSeq; WP_010896179.1; NC_002528.1.
DR   AlphaFoldDB; P57648; -.
DR   SMR; P57648; -.
DR   STRING; 107806.10039243; -.
DR   EnsemblBacteria; BAB13277; BAB13277; BAB13277.
DR   KEGG; buc:BU588; -.
DR   PATRIC; fig|107806.10.peg.593; -.
DR   eggNOG; COG2814; Bacteria.
DR   HOGENOM; CLU_001265_19_3_6; -.
DR   OMA; WRTAMLT; -.
DR   BioCyc; BAPH107806:GBZJ-581-MON; -.
DR   Proteomes; UP000001806; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR   Gene3D; 1.20.1250.20; -; 2.
DR   InterPro; IPR011701; MFS.
DR   InterPro; IPR020846; MFS_dom.
DR   InterPro; IPR036259; MFS_trans_sf.
DR   InterPro; IPR005829; Sugar_transporter_CS.
DR   Pfam; PF07690; MFS_1; 1.
DR   SUPFAM; SSF103473; SSF103473; 1.
DR   PROSITE; PS50850; MFS; 1.
DR   PROSITE; PS00216; SUGAR_TRANSPORT_1; 1.
PE   3: Inferred from homology;
KW   Cell membrane; Membrane; Reference proteome; Transmembrane;
KW   Transmembrane helix; Transport.
FT   CHAIN           1..410
FT                   /note="Uncharacterized transporter BU588"
FT                   /id="PRO_0000173415"
FT   TRANSMEM        27..47
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        63..83
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        97..117
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        118..138
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        145..165
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        180..200
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        228..248
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        254..274
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        293..313
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        316..332
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        355..375
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        378..398
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   410 AA;  46188 MW;  DED084E6CF94EB86 CRC64;
     MTLLKNKKQL LEKQYIKKNT KKFNQVILAL FSGGFATFSI LYCVQSILPM FSKQFYLTPA
     ESSLALSAAT ITMSLGMLFT GPLSDIIGRK SIMSTSLFIA AMLTMICSMM TSWISIVLLR
     ALTGLALSGV VAVAMTYISE EIHPNSLSFC MGLYISGNTI GGFLGRLLSS ILAEKFSWSI
     SLMVIGLFSF ISSCFFLYFL PPSKNFLSVS INFHKCLHRF YLQLKNRVLF FLFIIGFILM
     GSFVTIFNYI GYRLMLEPFF LCQSSIGLLS TIYLTGVYSS PKAGVLINKY NRNNILIVSL
     MLMIIGLFIT QYNQLFIIIL GLIIFSGGFF ASHSTASSWV GSYSNIAKIQ ATSLYLFFYY
     LGSSVFGTFG GFFWFHMQWL GISVFIITML FFGVFLSFKL KQKNFKNKYF