ID   Y588_HAEIN              Reviewed;         411 AA.
AC   Q57051; O05027;
DT   01-NOV-1997, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1996, sequence version 1.
DT   03-AUG-2022, entry version 110.
DE   RecName: Full=Uncharacterized hydrolase HI_0588;
DE            EC=3.-.-.-;
GN   OrderedLocusNames=HI_0588;
OS   Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Pasteurellales;
OC   Pasteurellaceae; Haemophilus.
OX   NCBI_TaxID=71421;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 51907 / DSM 11121 / KW20 / Rd;
RX   PubMed=7542800; DOI=10.1126/science.7542800;
RA   Fleischmann R.D., Adams M.D., White O., Clayton R.A., Kirkness E.F.,
RA   Kerlavage A.R., Bult C.J., Tomb J.-F., Dougherty B.A., Merrick J.M.,
RA   McKenney K., Sutton G.G., FitzHugh W., Fields C.A., Gocayne J.D.,
RA   Scott J.D., Shirley R., Liu L.-I., Glodek A., Kelley J.M., Weidman J.F.,
RA   Phillips C.A., Spriggs T., Hedblom E., Cotton M.D., Utterback T.R.,
RA   Hanna M.C., Nguyen D.T., Saudek D.M., Brandon R.C., Fine L.D.,
RA   Fritchman J.L., Fuhrmann J.L., Geoghagen N.S.M., Gnehm C.L., McDonald L.A.,
RA   Small K.V., Fraser C.M., Smith H.O., Venter J.C.;
RT   "Whole-genome random sequencing and assembly of Haemophilus influenzae
RT   Rd.";
RL   Science 269:496-512(1995).
RN   [2]
RP   IDENTIFICATION BY MASS SPECTROMETRY.
RC   STRAIN=ATCC 51907 / DSM 11121 / KW20 / Rd;
RX   PubMed=10675023;
RX   DOI=10.1002/(sici)1522-2683(20000101)21:2<411::aid-elps411>3.0.co;2-4;
RA   Langen H., Takacs B., Evers S., Berndt P., Lahm H.W., Wipf B., Gray C.,
RA   Fountoulakis M.;
RT   "Two-dimensional map of the proteome of Haemophilus influenzae.";
RL   Electrophoresis 21:411-429(2000).
CC   -!- SIMILARITY: Belongs to the peptidase M20 family. {ECO:0000305}.
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DR   EMBL; L42023; AAC22245.1; -; Genomic_DNA.
DR   PIR; D64079; D64079.
DR   RefSeq; NP_438746.1; NC_000907.1.
DR   RefSeq; WP_005694560.1; NC_000907.1.
DR   AlphaFoldDB; Q57051; -.
DR   SMR; Q57051; -.
DR   STRING; 71421.HI_0588; -.
DR   EnsemblBacteria; AAC22245; AAC22245; HI_0588.
DR   KEGG; hin:HI_0588; -.
DR   PATRIC; fig|71421.8.peg.609; -.
DR   eggNOG; COG0624; Bacteria.
DR   HOGENOM; CLU_024588_6_0_6; -.
DR   OMA; IWPHGRW; -.
DR   PhylomeDB; Q57051; -.
DR   BioCyc; HINF71421:G1GJ1-600-MON; -.
DR   Proteomes; UP000000579; Chromosome.
DR   GO; GO:0016813; F:hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines; IEA:InterPro.
DR   InterPro; IPR010158; Amidase_Cbmase.
DR   InterPro; IPR001261; ArgE/DapE_CS.
DR   InterPro; IPR036264; Bact_exopeptidase_dim_dom.
DR   InterPro; IPR002933; Peptidase_M20.
DR   InterPro; IPR011650; Peptidase_M20_dimer.
DR   PANTHER; PTHR32494; PTHR32494; 1.
DR   Pfam; PF07687; M20_dimer; 1.
DR   Pfam; PF01546; Peptidase_M20; 1.
DR   PIRSF; PIRSF001235; Amidase_carbamoylase; 1.
DR   SUPFAM; SSF55031; SSF55031; 1.
DR   TIGRFAMs; TIGR01879; hydantase; 1.
PE   1: Evidence at protein level;
KW   Hydrolase; Reference proteome.
FT   CHAIN           1..411
FT                   /note="Uncharacterized hydrolase HI_0588"
FT                   /id="PRO_0000061963"
SQ   SEQUENCE   411 AA;  45091 MW;  CA410B24651525AE CRC64;
     MSINLNRVQN LIEKLAFISS VPNELTRLAF TEEDEKAHNM IIELCKEYDL SIRRDSIGNL
     FIRKAGKEDF LPAVAFGSHI DTVVNAGKFD GPLGSVAGLE ILLQLCEQNI QTRYPLELII
     FTCEESSRFN FATLGSKVMC GIVNQEKLSS LRDKQGKGLS EAMAEVGMNF NLVNQAKRDA
     KEFKCFFELH IEQGPRLENE GKTIGVVTGI AAPIRAIVKI KGQADHSGAT AMHYRHDALL
     GGSELSLAIE RAAIQAGHST VATVGNITAK PGVMNVVPGY CELLVDIRGT HVQARDSVFE
     LLQEEISKVS EKRGLLIELQ LISKDNPIIL PENMVNQIAE TAHSLGYSYE IMPSGAGHDA
     MHMATLCPTG MIFIPSHLGI SHNPLEFTDW KDIEAGIKVL QKVILEQAEV C