ID   Y588_STAAR              Reviewed;         122 AA.
AC   Q6GJ86;
DT   05-SEP-2006, integrated into UniProtKB/Swiss-Prot.
DT   19-JUL-2004, sequence version 1.
DT   25-MAY-2022, entry version 83.
DE   RecName: Full=UPF0382 membrane protein SAR0588;
GN   OrderedLocusNames=SAR0588;
OS   Staphylococcus aureus (strain MRSA252).
OC   Bacteria; Firmicutes; Bacilli; Bacillales; Staphylococcaceae;
OC   Staphylococcus.
OX   NCBI_TaxID=282458;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=MRSA252;
RX   PubMed=15213324; DOI=10.1073/pnas.0402521101;
RA   Holden M.T.G., Feil E.J., Lindsay J.A., Peacock S.J., Day N.P.J.,
RA   Enright M.C., Foster T.J., Moore C.E., Hurst L., Atkin R., Barron A.,
RA   Bason N., Bentley S.D., Chillingworth C., Chillingworth T., Churcher C.,
RA   Clark L., Corton C., Cronin A., Doggett J., Dowd L., Feltwell T., Hance Z.,
RA   Harris B., Hauser H., Holroyd S., Jagels K., James K.D., Lennard N.,
RA   Line A., Mayes R., Moule S., Mungall K., Ormond D., Quail M.A.,
RA   Rabbinowitsch E., Rutherford K.M., Sanders M., Sharp S., Simmonds M.,
RA   Stevens K., Whitehead S., Barrell B.G., Spratt B.G., Parkhill J.;
RT   "Complete genomes of two clinical Staphylococcus aureus strains: evidence
RT   for the rapid evolution of virulence and drug resistance.";
RL   Proc. Natl. Acad. Sci. U.S.A. 101:9786-9791(2004).
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Multi-pass membrane
CC       protein {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the UPF0382 family. {ECO:0000305}.
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DR   EMBL; BX571856; CAG39608.1; -; Genomic_DNA.
DR   RefSeq; WP_000765183.1; NC_002952.2.
DR   AlphaFoldDB; Q6GJ86; -.
DR   KEGG; sar:SAR0588; -.
DR   HOGENOM; CLU_096548_3_3_9; -.
DR   OMA; QFYHTFA; -.
DR   OrthoDB; 1985942at2; -.
DR   Proteomes; UP000000596; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   InterPro; IPR006696; DUF423.
DR   PANTHER; PTHR43461; PTHR43461; 1.
DR   Pfam; PF04241; DUF423; 1.
PE   3: Inferred from homology;
KW   Cell membrane; Membrane; Transmembrane; Transmembrane helix.
FT   CHAIN           1..122
FT                   /note="UPF0382 membrane protein SAR0588"
FT                   /id="PRO_0000249031"
FT   TRANSMEM        3..23
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        46..66
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        69..89
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        98..118
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   122 AA;  13065 MW;  DF906EDDA0E22383 CRC64;
     MKLFIILGAL NAMMAVGTGA FGAHGLQGKI SDHYLSVWEK ATTYQMYHGL ALLIIGVISG
     TTSINVNWAG WLIFAGIIFF SGSLYILVLT QIKVLGAITP IGGVLFIIGW IMLIIATFKF
     AG