Y5900_ARATH
ID Y5900_ARATH Reviewed; 873 AA.
AC Q9FID8;
DT 24-NOV-2009, integrated into UniProtKB/Swiss-Prot.
DT 01-MAR-2001, sequence version 1.
DT 03-AUG-2022, entry version 132.
DE RecName: Full=Putative receptor-like protein kinase At5g39000;
DE EC=2.7.11.-;
DE Flags: Precursor;
GN OrderedLocusNames=At5g39000; ORFNames=MXF12.2;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=10048488; DOI=10.1093/dnares/5.6.379;
RA Asamizu E., Sato S., Kaneko T., Nakamura Y., Kotani H., Miyajima N.,
RA Tabata S.;
RT "Structural analysis of Arabidopsis thaliana chromosome 5. VIII. Sequence
RT features of the regions of 1,081,958 bp covered by seventeen physically
RT assigned P1 and TAC clones.";
RL DNA Res. 5:379-391(1998).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Single-pass type I
CC membrane protein {ECO:0000305}.
CC -!- SIMILARITY: Belongs to the protein kinase superfamily. Ser/Thr protein
CC kinase family. {ECO:0000255|PROSITE-ProRule:PRU00159}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AB016892; BAB10824.1; -; Genomic_DNA.
DR EMBL; CP002688; AED94385.1; -; Genomic_DNA.
DR RefSeq; NP_198716.1; NM_123262.2.
DR AlphaFoldDB; Q9FID8; -.
DR SMR; Q9FID8; -.
DR STRING; 3702.AT5G39000.1; -.
DR iPTMnet; Q9FID8; -.
DR PaxDb; Q9FID8; -.
DR PRIDE; Q9FID8; -.
DR ProteomicsDB; 242857; -.
DR EnsemblPlants; AT5G39000.1; AT5G39000.1; AT5G39000.
DR GeneID; 833892; -.
DR Gramene; AT5G39000.1; AT5G39000.1; AT5G39000.
DR KEGG; ath:AT5G39000; -.
DR Araport; AT5G39000; -.
DR TAIR; locus:2177202; AT5G39000.
DR eggNOG; KOG1187; Eukaryota.
DR HOGENOM; CLU_000288_42_5_1; -.
DR InParanoid; Q9FID8; -.
DR OMA; INYMENT; -.
DR OrthoDB; 684563at2759; -.
DR PhylomeDB; Q9FID8; -.
DR PRO; PR:Q9FID8; -.
DR Proteomes; UP000006548; Chromosome 5.
DR ExpressionAtlas; Q9FID8; baseline and differential.
DR Genevisible; Q9FID8; AT.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0005886; C:plasma membrane; IBA:GO_Central.
DR GO; GO:0009536; C:plastid; HDA:TAIR.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0004672; F:protein kinase activity; IBA:GO_Central.
DR GO; GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
DR GO; GO:0004714; F:transmembrane receptor protein tyrosine kinase activity; IEA:InterPro.
DR GO; GO:0046777; P:protein autophosphorylation; IBA:GO_Central.
DR GO; GO:0010038; P:response to metal ion; IGI:TAIR.
DR InterPro; IPR045272; ANXUR1-like.
DR InterPro; IPR011009; Kinase-like_dom_sf.
DR InterPro; IPR024788; Malectin-like_Carb-bd_dom.
DR InterPro; IPR000719; Prot_kinase_dom.
DR InterPro; IPR017441; Protein_kinase_ATP_BS.
DR InterPro; IPR001245; Ser-Thr/Tyr_kinase_cat_dom.
DR InterPro; IPR008271; Ser/Thr_kinase_AS.
DR PANTHER; PTHR27003; PTHR27003; 1.
DR Pfam; PF12819; Malectin_like; 1.
DR Pfam; PF07714; PK_Tyr_Ser-Thr; 1.
DR SMART; SM00220; S_TKc; 1.
DR SUPFAM; SSF56112; SSF56112; 1.
DR PROSITE; PS00107; PROTEIN_KINASE_ATP; 1.
DR PROSITE; PS50011; PROTEIN_KINASE_DOM; 1.
DR PROSITE; PS00108; PROTEIN_KINASE_ST; 1.
PE 3: Inferred from homology;
KW ATP-binding; Glycoprotein; Kinase; Membrane; Nucleotide-binding;
KW Reference proteome; Serine/threonine-protein kinase; Signal; Transferase;
KW Transmembrane; Transmembrane helix.
FT SIGNAL 1..21
FT /evidence="ECO:0000255"
FT CHAIN 22..873
FT /note="Putative receptor-like protein kinase At5g39000"
FT /id="PRO_0000388798"
FT TOPO_DOM 22..445
FT /note="Extracellular"
FT /evidence="ECO:0000255"
FT TRANSMEM 446..466
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 467..873
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT DOMAIN 518..803
FT /note="Protein kinase"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00159"
FT REGION 472..494
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 813..843
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 475..494
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT ACT_SITE 646
FT /note="Proton acceptor"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00159,
FT ECO:0000255|PROSITE-ProRule:PRU10027"
FT BINDING 524..532
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00159"
FT BINDING 547
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00159"
FT CARBOHYD 49
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 64
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 138
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 168
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 216
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 266
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 300
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 340
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 437
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
SQ SEQUENCE 873 AA; 97164 MW; B2879DE5BC7337A7 CRC64;
MIRHALLIFS ILVSTPIVGE GATSTYEPTD VFLFNCGDTS NNVDVSGRNW TAENQKILSS
NLVNASFTAQ ASYQESGVSQ IPYMTARIFR SEFTYSFPVT PGSNFLRLYF YPTRYGSQFN
AVKSFFSVKV NGFTLLNNFS ADLTVKASKP QTEFIIKEFI IPVYQTLNLT FTPSLDSLAF
VNGIEIVSIP NRFYSKGGFD DVITNVGSSV DFHIENSTAF ETVYRLNVGG KTVGDSGMFR
RWVSDDEIIL SESSGISPIV PDIKINYTEK TPSYVAPDDV YATSRSMGNA DHPEQNLNFN
LTWLFTVDAG FSYLVRLHFC ETLSEVNKEG QRVFSIFIEN QTATLEMDVF RMSGGSWIPM
YLDYTVIAGS GSGRRHDLRL DLHPLVSINP KYYDAILNGV EILKMNDPDG NLAGPNPDPL
VSPDLIPNRA TPRIRKNKSH ILPITLAVVG SLVVLAMFVV GVLVIMKKKK KSKPSTNSSW
CPLPHGTDST NTKPAKSLPA DLCRRFSIFE IKSATNDFED KLIIGVGGFG SVYKGQIDGG
ATLVAVKRLE ITSNQGAKEF ETELEMLSKL RHVHLVSLIG YCDEDNEMVL VYEYMPHGTL
KDHLFRRDKT SDPPLSWKRR LEICIGAARG LQYLHTGAKY TIIHRDIKTT NILLDENFVT
KVSDFGLSRV GPTSASQTHV STVVKGTFGY LDPEYYRRQV LTEKSDVYSF GVVLLEVLCC
RPIRMQSVPP EQADLIRWVK SNYRRGTVDQ IIDSDLSADI TSTSLEKFCE IAVRCVQDRG
MERPPMNDVV WALEFALQLH ETAKKKNDNV ESLDLMPSGE VGTTTDGEDD LFSRTTGHVG
KSTTTDDSVL VVGDERSGSS WGVFSEINEP KAR
