Y5909_MYXXD
ID Y5909_MYXXD Reviewed; 253 AA.
AC P25970; Q1CZX7;
DT 01-MAY-1992, integrated into UniProtKB/Swiss-Prot.
DT 19-SEP-2006, sequence version 2.
DT 03-AUG-2022, entry version 125.
DE RecName: Full=Uncharacterized oxidoreductase MXAN_5909;
DE EC=1.-.-.-;
GN OrderedLocusNames=MXAN_5909;
OS Myxococcus xanthus (strain DK1622).
OC Bacteria; Proteobacteria; Deltaproteobacteria; Myxococcales;
OC Cystobacterineae; Myxococcaceae; Myxococcus.
OX NCBI_TaxID=246197;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX PubMed=1730672; DOI=10.1016/s0021-9258(18)48357-3;
RA Kimsey H.H., Kaiser D.;
RT "The orotidine-5'-monophosphate decarboxylase gene of Myxococcus xanthus.
RT Comparison to the OMP decarboxylase gene family.";
RL J. Biol. Chem. 267:819-824(1992).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DK1622;
RX PubMed=17015832; DOI=10.1073/pnas.0607335103;
RA Goldman B.S., Nierman W.C., Kaiser D., Slater S.C., Durkin A.S., Eisen J.,
RA Ronning C.M., Barbazuk W.B., Blanchard M., Field C., Halling C., Hinkle G.,
RA Iartchuk O., Kim H.S., Mackenzie C., Madupu R., Miller N., Shvartsbeyn A.,
RA Sullivan S.A., Vaudin M., Wiegand R., Kaplan H.B.;
RT "Evolution of sensory complexity recorded in a myxobacterial genome.";
RL Proc. Natl. Acad. Sci. U.S.A. 103:15200-15205(2006).
CC -!- SIMILARITY: Belongs to the short-chain dehydrogenases/reductases (SDR)
CC family. {ECO:0000305}.
CC -!- SEQUENCE CAUTION:
CC Sequence=M79325; Type=Frameshift; Evidence={ECO:0000305};
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DR EMBL; M79325; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; CP000113; ABF86550.1; -; Genomic_DNA.
DR RefSeq; WP_011555860.1; NC_008095.1.
DR AlphaFoldDB; P25970; -.
DR SMR; P25970; -.
DR STRING; 246197.MXAN_5909; -.
DR EnsemblBacteria; ABF86550; ABF86550; MXAN_5909.
DR GeneID; 41363147; -.
DR KEGG; mxa:MXAN_5909; -.
DR eggNOG; COG0300; Bacteria.
DR HOGENOM; CLU_010194_2_1_7; -.
DR OMA; AEMVMEV; -.
DR OrthoDB; 1186478at2; -.
DR Proteomes; UP000002402; Chromosome.
DR GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR InterPro; IPR020904; Sc_DH/Rdtase_CS.
DR InterPro; IPR002347; SDR_fam.
DR Pfam; PF00106; adh_short; 1.
DR PRINTS; PR00081; GDHRDH.
DR PRINTS; PR00080; SDRFAMILY.
DR SUPFAM; SSF51735; SSF51735; 1.
DR PROSITE; PS00061; ADH_SHORT; 1.
PE 3: Inferred from homology;
KW Oxidoreductase; Reference proteome.
FT CHAIN 1..253
FT /note="Uncharacterized oxidoreductase MXAN_5909"
FT /id="PRO_0000054891"
FT ACT_SITE 155
FT /note="Proton acceptor"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU10001"
FT BINDING 10..34
FT /ligand="NADP(+)"
FT /ligand_id="ChEBI:CHEBI:58349"
FT /evidence="ECO:0000250"
FT BINDING 142
FT /ligand="substrate"
FT /evidence="ECO:0000250"
FT CONFLICT 46..47
FT /note="LR -> A (in Ref. 1)"
FT /evidence="ECO:0000305"
FT CONFLICT 51..62
FT /note="QAAGVTVEPVEL -> PGGRRHRGARGV (in Ref. 1)"
FT /evidence="ECO:0000305"
FT CONFLICT 150..154
FT /note="AGHAA -> PATR (in Ref. 1)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 253 AA; 26969 MW; F47D8F1834EC7C71 CRC64;
MAEMSYRTAL VTGASSGLGR GLALWLARRG VRVFAAGRRL PQLQALRDEA QAAGVTVEPV
ELDVTKADAT LERIRALDAE AGGLDLVVAN AGVGGTTNAK RLPWERVRGI IDTNVTGAAA
TLSAVLPQMV ERKRGHLVGV SSLAGFRGLA GHAAYSASKA FLSTFMESLR VDLRGTGVRV
TCIYPGFVKS ELTATNNFPM PFLMETHDAV ELMGKGIVRG DAEVSFPWQL AVPTRMAKVL
PNPLFDAAAR RLR
