ID   Y591_CLOBH              Reviewed;         170 AA.
AC   A5HZD5; A7G192;
DT   15-JAN-2008, integrated into UniProtKB/Swiss-Prot.
DT   26-JUN-2007, sequence version 1.
DT   03-AUG-2022, entry version 63.
DE   RecName: Full=UPF0316 protein CBO0591/CLC_0646 {ECO:0000255|HAMAP-Rule:MF_01515};
GN   OrderedLocusNames=CBO0591, CLC_0646;
OS   Clostridium botulinum (strain Hall / ATCC 3502 / NCTC 13319 / Type A).
OC   Bacteria; Firmicutes; Clostridia; Eubacteriales; Clostridiaceae;
OC   Clostridium.
OX   NCBI_TaxID=441771;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Hall / ATCC 3502 / NCTC 13319 / Type A;
RX   PubMed=17519437; DOI=10.1101/gr.6282807;
RA   Sebaihia M., Peck M.W., Minton N.P., Thomson N.R., Holden M.T.G.,
RA   Mitchell W.J., Carter A.T., Bentley S.D., Mason D.R., Crossman L.,
RA   Paul C.J., Ivens A., Wells-Bennik M.H.J., Davis I.J., Cerdeno-Tarraga A.M.,
RA   Churcher C., Quail M.A., Chillingworth T., Feltwell T., Fraser A.,
RA   Goodhead I., Hance Z., Jagels K., Larke N., Maddison M., Moule S.,
RA   Mungall K., Norbertczak H., Rabbinowitsch E., Sanders M., Simmonds M.,
RA   White B., Whithead S., Parkhill J.;
RT   "Genome sequence of a proteolytic (Group I) Clostridium botulinum strain
RT   Hall A and comparative analysis of the clostridial genomes.";
RL   Genome Res. 17:1082-1092(2007).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Hall / ATCC 3502 / NCTC 13319 / Type A;
RX   PubMed=18060065; DOI=10.1371/journal.pone.0001271;
RA   Smith T.J., Hill K.K., Foley B.T., Detter J.C., Munk A.C., Bruce D.C.,
RA   Doggett N.A., Smith L.A., Marks J.D., Xie G., Brettin T.S.;
RT   "Analysis of the neurotoxin complex genes in Clostridium botulinum A1-A4
RT   and B1 strains: BoNT/A3, /Ba4 and /B1 clusters are located within
RT   plasmids.";
RL   PLoS ONE 2:E1271-E1271(2007).
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000255|HAMAP-Rule:MF_01515};
CC       Multi-pass membrane protein {ECO:0000255|HAMAP-Rule:MF_01515}.
CC   -!- SIMILARITY: Belongs to the UPF0316 family. {ECO:0000255|HAMAP-
CC       Rule:MF_01515}.
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DR   EMBL; CP000727; ABS38392.1; -; Genomic_DNA.
DR   EMBL; AM412317; CAL82144.1; -; Genomic_DNA.
DR   RefSeq; WP_003357138.1; NC_009698.1.
DR   RefSeq; YP_001253133.1; NC_009495.1.
DR   RefSeq; YP_001386526.1; NC_009698.1.
DR   AlphaFoldDB; A5HZD5; -.
DR   SMR; A5HZD5; -.
DR   GeneID; 5184846; -.
DR   KEGG; cbh:CLC_0646; -.
DR   KEGG; cbo:CBO0591; -.
DR   PATRIC; fig|413999.7.peg.591; -.
DR   HOGENOM; CLU_106166_0_0_9; -.
DR   OMA; KLALGYI; -.
DR   PRO; PR:A5HZD5; -.
DR   Proteomes; UP000001986; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   HAMAP; MF_01515; UPF0316; 1.
DR   InterPro; IPR019264; DUF2179.
DR   InterPro; IPR044035; DUF5698.
DR   InterPro; IPR022930; UPF0316.
DR   PANTHER; PTHR40060; PTHR40060; 1.
DR   Pfam; PF10035; DUF2179; 1.
DR   Pfam; PF18955; DUF5698; 1.
PE   3: Inferred from homology;
KW   Cell membrane; Membrane; Reference proteome; Transmembrane;
KW   Transmembrane helix.
FT   CHAIN           1..170
FT                   /note="UPF0316 protein CBO0591/CLC_0646"
FT                   /id="PRO_0000315257"
FT   TRANSMEM        1..21
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01515"
FT   TRANSMEM        36..56
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01515"
SQ   SEQUENCE   170 AA;  19098 MW;  AED18AA5A1A7E312 CRC64;
     MLSYYAFIFF AKIMEVALMT IRTVLITRGE KLYGSIIGFI EVTIWLYVTS SVLSGIKDDP
     IRMVVYALGF TCGNYMGCVI EEKLAIGLLT INVITSESDG KRLAEILRDE NVGVTMVDAE
     GKIEQKKMLI IHAKRKRREE IIRTIEGSDI NAMISVNDIK TVYGGYGIRK