ID   Y592_MYCSK              Reviewed;         249 AA.
AC   A1UAF0;
DT   20-JAN-2009, integrated into UniProtKB/Swiss-Prot.
DT   06-FEB-2007, sequence version 1.
DT   03-AUG-2022, entry version 77.
DE   RecName: Full=Putative S-adenosyl-L-methionine-dependent methyltransferase Mkms_0592;
DE            EC=2.1.1.-;
GN   OrderedLocusNames=Mkms_0592;
OS   Mycobacterium sp. (strain KMS).
OC   Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
OC   Mycobacterium; unclassified Mycobacterium.
OX   NCBI_TaxID=189918;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=KMS;
RG   US DOE Joint Genome Institute;
RA   Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C.,
RA   Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S.,
RA   Kiss H., Brettin T., Bruce D., Han C., Tapia R., Gilna P., Schmutz J.,
RA   Larimer F., Land M., Hauser L., Kyrpides N., Mikhailova N., Miller C.D.,
RA   Richardson P.;
RT   "Complete sequence of chromosome of Mycobacterium sp. KMS.";
RL   Submitted (DEC-2006) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Exhibits S-adenosyl-L-methionine-dependent methyltransferase
CC       activity. {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the UPF0677 family. {ECO:0000305}.
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DR   EMBL; CP000518; ABL89808.1; -; Genomic_DNA.
DR   RefSeq; WP_011768042.1; NC_008705.1.
DR   AlphaFoldDB; A1UAF0; -.
DR   SMR; A1UAF0; -.
DR   STRING; 189918.Mkms_0592; -.
DR   EnsemblBacteria; ABL89808; ABL89808; Mkms_0592.
DR   KEGG; mkm:Mkms_0592; -.
DR   HOGENOM; CLU_056160_2_1_11; -.
DR   OMA; GSAASMW; -.
DR   OrthoDB; 847145at2; -.
DR   GO; GO:0008168; F:methyltransferase activity; IEA:UniProtKB-KW.
DR   GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR   Gene3D; 3.40.50.150; -; 1.
DR   InterPro; IPR011610; CHP00027_methylltransferase.
DR   InterPro; IPR007213; Ppm1/Ppm2/Tcmp.
DR   InterPro; IPR029063; SAM-dependent_MTases_sf.
DR   Pfam; PF04072; LCM; 1.
DR   SUPFAM; SSF53335; SSF53335; 1.
DR   TIGRFAMs; TIGR00027; mthyl_TIGR00027; 1.
PE   3: Inferred from homology;
KW   Methyltransferase; S-adenosyl-L-methionine; Transferase.
FT   CHAIN           1..249
FT                   /note="Putative S-adenosyl-L-methionine-dependent
FT                   methyltransferase Mkms_0592"
FT                   /id="PRO_0000361214"
FT   BINDING         111
FT                   /ligand="S-adenosyl-L-methionine"
FT                   /ligand_id="ChEBI:CHEBI:59789"
FT                   /evidence="ECO:0000250"
FT   BINDING         141..142
FT                   /ligand="S-adenosyl-L-methionine"
FT                   /ligand_id="ChEBI:CHEBI:59789"
FT                   /evidence="ECO:0000250"
SQ   SEQUENCE   249 AA;  27032 MW;  A7011D1B4FBF6408 CRC64;
     MTTPDGIVSA LAVALARQSE SHADCPLFND PYAQVFIDAA LSRGCQLPSD ETSERINGIA
     NYASSRTKWF DEYFIAAGAH GLEQMVIVAA GLDARAWRLP WVAGTTLFEI DHPGVLKFKN
     EALHEHGESP SVSRYVPVPA DLSDGWSERL RDAGFDVSEP TAWAVEGLLP YVADGPHLLF
     DRIHEISPAG SRLAVEAVGT GVADWLSTQG WQVTMIGAQE LMTRYGRCGD HSDTDAGMDT
     VFVNATRTR