ID   Y594_STRPI              Reviewed;         182 AA.
AC   B1IA22;
DT   14-APR-2009, integrated into UniProtKB/Swiss-Prot.
DT   29-APR-2008, sequence version 1.
DT   25-MAY-2022, entry version 65.
DE   RecName: Full=UPF0397 protein SPH_0594 {ECO:0000255|HAMAP-Rule:MF_01572};
GN   OrderedLocusNames=SPH_0594;
OS   Streptococcus pneumoniae (strain Hungary19A-6).
OC   Bacteria; Firmicutes; Bacilli; Lactobacillales; Streptococcaceae;
OC   Streptococcus.
OX   NCBI_TaxID=487214;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Hungary19A-6;
RX   PubMed=21034474; DOI=10.1186/gb-2010-11-10-r107;
RA   Donati C., Hiller N.L., Tettelin H., Muzzi A., Croucher N.J.,
RA   Angiuoli S.V., Oggioni M., Dunning Hotopp J.C., Hu F.Z., Riley D.R.,
RA   Covacci A., Mitchell T.J., Bentley S.D., Kilian M., Ehrlich G.D.,
RA   Rappuoli R., Moxon E.R., Masignani V.;
RT   "Structure and dynamics of the pan-genome of Streptococcus pneumoniae and
RT   closely related species.";
RL   Genome Biol. 11:R107.1-R107.19(2010).
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000255|HAMAP-Rule:MF_01572};
CC       Multi-pass membrane protein {ECO:0000255|HAMAP-Rule:MF_01572}.
CC   -!- SIMILARITY: Belongs to the UPF0397 family. {ECO:0000255|HAMAP-
CC       Rule:MF_01572}.
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DR   EMBL; CP000936; ACA36532.1; -; Genomic_DNA.
DR   RefSeq; WP_000403171.1; NC_010380.1.
DR   AlphaFoldDB; B1IA22; -.
DR   SMR; B1IA22; -.
DR   EnsemblBacteria; ACA36532; ACA36532; SPH_0594.
DR   GeneID; 66805666; -.
DR   KEGG; spv:SPH_0594; -.
DR   HOGENOM; CLU_120023_0_0_9; -.
DR   OMA; WWSWVIA; -.
DR   Proteomes; UP000002163; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   HAMAP; MF_01572; UPF0397; 1.
DR   InterPro; IPR009825; ECF_substrate-spec-like.
DR   InterPro; IPR022914; UPF0397.
DR   Pfam; PF07155; ECF-ribofla_trS; 1.
PE   3: Inferred from homology;
KW   Cell membrane; Membrane; Transmembrane; Transmembrane helix.
FT   CHAIN           1..182
FT                   /note="UPF0397 protein SPH_0594"
FT                   /id="PRO_1000200763"
FT   TRANSMEM        10..30
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01572"
FT   TRANSMEM        46..66
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01572"
FT   TRANSMEM        73..93
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01572"
FT   TRANSMEM        109..129
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01572"
FT   TRANSMEM        148..168
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01572"
SQ   SEQUENCE   182 AA;  19301 MW;  3FCC75404E4055CD CRC64;
     MEIKFTIKQV VAVGIGAALF VVIGMINIPT PVPNTSIQLQ YAVQALLSII FGPIIGLLVG
     VIGHAIKDSL AGYGLWWTWI IASGLFGLVV GLFRKYVRVI NGVFDWKDIL IFNLIQLLAN
     ALVWGVLAPL GDVVIYQEAA EKVFAQGIVA GIANGVSVAI AGTLLLLAYA GTQTRAGSLK
     KD