ID   Y5975_DICDI             Reviewed;         917 AA.
AC   Q54MG4;
DT   24-NOV-2009, integrated into UniProtKB/Swiss-Prot.
DT   24-MAY-2005, sequence version 1.
DT   25-MAY-2022, entry version 69.
DE   RecName: Full=von Willebrand factor A domain-containing protein DDB_G0285975;
GN   ORFNames=DDB_G0285975;
OS   Dictyostelium discoideum (Slime mold).
OC   Eukaryota; Amoebozoa; Evosea; Eumycetozoa; Dictyostelia; Dictyosteliales;
OC   Dictyosteliaceae; Dictyostelium.
OX   NCBI_TaxID=44689;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=AX4;
RX   PubMed=15875012; DOI=10.1038/nature03481;
RA   Eichinger L., Pachebat J.A., Gloeckner G., Rajandream M.A., Sucgang R.,
RA   Berriman M., Song J., Olsen R., Szafranski K., Xu Q., Tunggal B.,
RA   Kummerfeld S., Madera M., Konfortov B.A., Rivero F., Bankier A.T.,
RA   Lehmann R., Hamlin N., Davies R., Gaudet P., Fey P., Pilcher K., Chen G.,
RA   Saunders D., Sodergren E.J., Davis P., Kerhornou A., Nie X., Hall N.,
RA   Anjard C., Hemphill L., Bason N., Farbrother P., Desany B., Just E.,
RA   Morio T., Rost R., Churcher C.M., Cooper J., Haydock S., van Driessche N.,
RA   Cronin A., Goodhead I., Muzny D.M., Mourier T., Pain A., Lu M., Harper D.,
RA   Lindsay R., Hauser H., James K.D., Quiles M., Madan Babu M., Saito T.,
RA   Buchrieser C., Wardroper A., Felder M., Thangavelu M., Johnson D.,
RA   Knights A., Loulseged H., Mungall K.L., Oliver K., Price C., Quail M.A.,
RA   Urushihara H., Hernandez J., Rabbinowitsch E., Steffen D., Sanders M.,
RA   Ma J., Kohara Y., Sharp S., Simmonds M.N., Spiegler S., Tivey A.,
RA   Sugano S., White B., Walker D., Woodward J.R., Winckler T., Tanaka Y.,
RA   Shaulsky G., Schleicher M., Weinstock G.M., Rosenthal A., Cox E.C.,
RA   Chisholm R.L., Gibbs R.A., Loomis W.F., Platzer M., Kay R.R.,
RA   Williams J.G., Dear P.H., Noegel A.A., Barrell B.G., Kuspa A.;
RT   "The genome of the social amoeba Dictyostelium discoideum.";
RL   Nature 435:43-57(2005).
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DR   EMBL; AAFI02000082; EAL64446.1; -; Genomic_DNA.
DR   RefSeq; XP_637950.1; XM_632858.1.
DR   AlphaFoldDB; Q54MG4; -.
DR   SMR; Q54MG4; -.
DR   PaxDb; Q54MG4; -.
DR   PRIDE; Q54MG4; -.
DR   EnsemblProtists; EAL64446; EAL64446; DDB_G0285975.
DR   GeneID; 8625377; -.
DR   KEGG; ddi:DDB_G0285975; -.
DR   dictyBase; DDB_G0285975; -.
DR   eggNOG; ENOG502QRPK; Eukaryota.
DR   HOGENOM; CLU_327738_0_0_1; -.
DR   InParanoid; Q54MG4; -.
DR   PhylomeDB; Q54MG4; -.
DR   PRO; PR:Q54MG4; -.
DR   Proteomes; UP000002195; Chromosome 4.
DR   GO; GO:0016020; C:membrane; IEA:InterPro.
DR   GO; GO:0016192; P:vesicle-mediated transport; IEA:InterPro.
DR   Gene3D; 3.40.50.410; -; 1.
DR   InterPro; IPR010989; SNARE.
DR   InterPro; IPR000727; T_SNARE_dom.
DR   InterPro; IPR013694; VIT.
DR   InterPro; IPR002035; VWF_A.
DR   InterPro; IPR036465; vWFA_dom_sf.
DR   Pfam; PF08487; VIT; 1.
DR   Pfam; PF13768; VWA_3; 1.
DR   SMART; SM00609; VIT; 1.
DR   SMART; SM00327; VWA; 1.
DR   SUPFAM; SSF47661; SSF47661; 1.
DR   SUPFAM; SSF53300; SSF53300; 1.
DR   PROSITE; PS50192; T_SNARE; 1.
DR   PROSITE; PS51468; VIT; 1.
DR   PROSITE; PS50234; VWFA; 1.
PE   4: Predicted;
KW   Coiled coil; Reference proteome.
FT   CHAIN           1..917
FT                   /note="von Willebrand factor A domain-containing protein
FT                   DDB_G0285975"
FT                   /id="PRO_0000389212"
FT   DOMAIN          87..215
FT                   /note="VIT"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00801"
FT   DOMAIN          339..507
FT                   /note="VWFA"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00219"
FT   DOMAIN          679..741
FT                   /note="t-SNARE coiled-coil homology"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00202"
FT   REGION          12..51
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          751..822
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        771..822
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   917 AA;  103523 MW;  F0E32F65B3D67212 CRC64;
     MLQSLKNVFF SDTTTTTTPT TPTTPTTPTT TPTTTTTPTT TPTTTTTSTT PISNLSIKRD
     IGNINDYKNA NYFNYYRILE NKYNYLRYNT GLKNISNNET FKLIDFTIDS EMNNTCITSN
     WNQKYSNNSS TPVEGVYKIP LAPYSVVSGF TVEYQDKVFI GKIKSKEKAQ NQYSDSIASG
     GQAFLAEKTQ DGQFSFRIGN LPPNENVTIH LTIISEVCPH LSSLQNCFHR FLFPNYSFNF
     QFNLNIKLTL PIKTIELLYY PNKDIKFKEN SNNKEATLTF SSNNGIDDDI VCIVEPENDI
     ERPQSIIEHS KLNNTYAVSV NFTPSFSHLT SDDVNQKSEF IFLIDCSGSM SGEPIKKAKR
     ALEIIIRSLN ENCKFNIYCF GSRFTKAFDN SKMYNDETLK EISGYVEKID ADLGGTELLP
     PIRDILSTES DFEYPRQLFI LTDGEVSERD SLINYVATES NNTRIFTYGI GNSVDTELVI
     GLSKACKGYY EMIKDNSNFE EQVMKLVSIA FEPTLSNIKV DWGTELQIEQ GPTKIRPLYS
     GETLIVYALL KDNKIPQSTV QVSLIGDGPT GSKLEFPITL DFSKTIDYEN NSVHTLAAFN
     IIKDLEEVER KGNHSNNRDR IEELGKNYGL ISKYTSYIVT AASEQVTEET MKTLNIIQIP
     TTTTTSHTNF ETEEDSDDLF SSENRNQTLA NISNDMEKIK DIFDDISRLI SEQSCMLNEI
     GDANIEASTL GINSIPQKSN IFSKITSFFS SPSEVSTSKS NFDSDIGSEE RRNNNNNNNN
     NNININNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNSD NSDSLLKLIR LQKANGSWSS
     PFSEFKIDLS KKPSNIDNDD IWITLIVINK ILNDYPTQQS QYDLVIQKAS KWVKQQLTRL
     NIPNQYGSLL ATSKLYI