ID   Y608_HAEIN              Reviewed;         461 AA.
AC   Q57486;
DT   01-NOV-1997, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1996, sequence version 1.
DT   03-AUG-2022, entry version 119.
DE   RecName: Full=Uncharacterized transporter HI_0608;
GN   OrderedLocusNames=HI_0608;
OS   Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Pasteurellales;
OC   Pasteurellaceae; Haemophilus.
OX   NCBI_TaxID=71421;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 51907 / DSM 11121 / KW20 / Rd;
RX   PubMed=7542800; DOI=10.1126/science.7542800;
RA   Fleischmann R.D., Adams M.D., White O., Clayton R.A., Kirkness E.F.,
RA   Kerlavage A.R., Bult C.J., Tomb J.-F., Dougherty B.A., Merrick J.M.,
RA   McKenney K., Sutton G.G., FitzHugh W., Fields C.A., Gocayne J.D.,
RA   Scott J.D., Shirley R., Liu L.-I., Glodek A., Kelley J.M., Weidman J.F.,
RA   Phillips C.A., Spriggs T., Hedblom E., Cotton M.D., Utterback T.R.,
RA   Hanna M.C., Nguyen D.T., Saudek D.M., Brandon R.C., Fine L.D.,
RA   Fritchman J.L., Fuhrmann J.L., Geoghagen N.S.M., Gnehm C.L., McDonald L.A.,
RA   Small K.V., Fraser C.M., Smith H.O., Venter J.C.;
RT   "Whole-genome random sequencing and assembly of Haemophilus influenzae
RT   Rd.";
RL   Science 269:496-512(1995).
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Multi-pass membrane
CC       protein {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the SLC13A/DASS transporter (TC 2.A.47) family.
CC       NADC subfamily. {ECO:0000305}.
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DR   EMBL; L42023; AAC22267.1; -; Genomic_DNA.
DR   PIR; I64080; I64080.
DR   RefSeq; NP_438766.1; NC_000907.1.
DR   RefSeq; WP_010869019.1; NC_000907.1.
DR   AlphaFoldDB; Q57486; -.
DR   SMR; Q57486; -.
DR   STRING; 71421.HI_0608; -.
DR   EnsemblBacteria; AAC22267; AAC22267; HI_0608.
DR   KEGG; hin:HI_0608; -.
DR   PATRIC; fig|71421.8.peg.632; -.
DR   eggNOG; COG0471; Bacteria.
DR   HOGENOM; CLU_005170_0_2_6; -.
DR   OMA; NFSICLM; -.
DR   PhylomeDB; Q57486; -.
DR   BioCyc; HINF71421:G1GJ1-627-MON; -.
DR   Proteomes; UP000000579; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IBA:GO_Central.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR   GO; GO:0098656; P:anion transmembrane transport; IBA:GO_Central.
DR   InterPro; IPR031312; Na/sul_symport_CS.
DR   InterPro; IPR001898; SLC13A/DASS.
DR   Pfam; PF00939; Na_sulph_symp; 1.
DR   TIGRFAMs; TIGR00785; dass; 1.
DR   PROSITE; PS01271; NA_SULFATE; 1.
PE   3: Inferred from homology;
KW   Cell membrane; Membrane; Reference proteome; Transmembrane;
KW   Transmembrane helix; Transport.
FT   CHAIN           1..461
FT                   /note="Uncharacterized transporter HI_0608"
FT                   /id="PRO_0000172505"
FT   TRANSMEM        13..33
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        54..74
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        81..101
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        120..140
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        170..190
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        211..231
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        256..276
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        286..306
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        314..334
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        349..369
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        377..397
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        399..419
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        439..459
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   461 AA;  49762 MW;  B5E6F6965B38EF06 CRC64;
     MGEMASLRSH KNGIIFILDI VLFFVLLNVL PFEPKANSGL ALLAFIAVLW LSEALHVTIT
     ALLVPLLAVA LGLVSTKQAL VGFADPTIFL FFGGFSLATA LHIQKLDKLI ANKIMALARG
     NLFIAVIYLF LITAFLSMWM SNTATAAMML PLAMGILSQL DREKDHNTYV FVLLGIAYSA
     SIGGMGTLVG SPPNAIVASN LNLTFSDWLW YGLPIMIILL PLMIGILYII FKPKLHLNFE
     QTFENIEMNP MRILTFIIFP VIALTWIFSG KINPFISGLL GLQKNIASFD SIVALLAAIV
     ICSTGVASWK QIQSNTDWGV LMLFGGGLTL SAVLKDSGAS KILADSIVFM IDGQHFYLIG
     LLVAAFIIFL TEFTSNTASA ALLVPIFISI AQSLGMPEIG LALIIGIGAS CAFMLPVATP
     PNAIVFGSGQ VKQSEMVKVG FLLNLVCVVV IATMGYMFWL K