CASK_PECTA
ID CASK_PECTA Reviewed; 146 AA.
AC Q28794;
DT 01-NOV-1997, integrated into UniProtKB/Swiss-Prot.
DT 01-NOV-1996, sequence version 1.
DT 25-MAY-2022, entry version 57.
DE RecName: Full=Kappa-casein;
DE Flags: Fragment;
GN Name=CSN3; Synonyms=CSN10, CSNK;
OS Pecari tajacu (Collared peccary) (Tayassu tajacu).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Artiodactyla; Suina; Tayassuidae; Pecari.
OX NCBI_TaxID=9829;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX PubMed=8752004; DOI=10.1093/oxfordjournals.molbev.a025663;
RA Gatesy J., Hayashi C., Cronin M.A., Arctander P.;
RT "Evidence from milk casein genes that cetaceans are close relatives of
RT hippopotamid artiodactyls.";
RL Mol. Biol. Evol. 13:954-963(1996).
CC -!- FUNCTION: Kappa-casein stabilizes micelle formation, preventing casein
CC precipitation in milk.
CC -!- SUBCELLULAR LOCATION: Secreted.
CC -!- TISSUE SPECIFICITY: Mammary gland specific. Secreted in milk.
CC -!- SIMILARITY: Belongs to the kappa-casein family. {ECO:0000305}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; U53891; AAB08416.1; -; Genomic_DNA.
DR AlphaFoldDB; Q28794; -.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR InterPro; IPR000117; Casein_kappa.
DR PANTHER; PTHR11470; PTHR11470; 1.
DR Pfam; PF00997; Casein_kappa; 1.
PE 2: Evidence at transcript level;
KW Glycoprotein; Milk protein; Phosphoprotein; Secreted.
FT CHAIN <1..146
FT /note="Kappa-casein"
FT /id="PRO_0000144121"
FT SITE 80..81
FT /note="Cleavage; by chymosin/rennin"
FT /evidence="ECO:0000250"
FT MOD_RES 143
FT /note="Phosphoserine"
FT /evidence="ECO:0000250|UniProtKB:P02670"
FT CARBOHYD 107
FT /note="O-linked (GalNAc...) threonine"
FT /evidence="ECO:0000250|UniProtKB:P02668"
FT CARBOHYD 112
FT /note="O-linked (GalNAc...) threonine"
FT /evidence="ECO:0000250|UniProtKB:P02668"
FT CARBOHYD 118
FT /note="O-linked (GalNAc...) threonine"
FT /evidence="ECO:0000250|UniProtKB:P02668"
FT NON_TER 1
SQ SEQUENCE 146 AA; 16406 MW; 133188256EC2C038 CRC64;
LFNEERFRSI PIHYRLNRIP SYGFIFYQHR SAASTNNQFI PYPFYARPVA VRPHAQKPQW
QDQPNVYPPT GARRPRPHAS FIAIPPKKNQ DTTAIPAINS IATVEPTLIP TTEPVVNTVV
IPEAASEFLI TNTPETTAVQ VSSTVV