ID   Y614_PYRHO              Reviewed;         332 AA.
AC   O58348;
DT   30-MAY-2000, integrated into UniProtKB/Swiss-Prot.
DT   01-MAY-1999, sequence version 2.
DT   25-MAY-2022, entry version 104.
DE   RecName: Full=Uncharacterized protein PH0614;
DE   Flags: Precursor;
GN   OrderedLocusNames=PH0614;
OS   Pyrococcus horikoshii (strain ATCC 700860 / DSM 12428 / JCM 9974 / NBRC
OS   100139 / OT-3).
OC   Archaea; Euryarchaeota; Thermococci; Thermococcales; Thermococcaceae;
OC   Pyrococcus.
OX   NCBI_TaxID=70601;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 700860 / DSM 12428 / JCM 9974 / NBRC 100139 / OT-3;
RX   PubMed=9679194; DOI=10.1093/dnares/5.2.55;
RA   Kawarabayasi Y., Sawada M., Horikawa H., Haikawa Y., Hino Y., Yamamoto S.,
RA   Sekine M., Baba S., Kosugi H., Hosoyama A., Nagai Y., Sakai M., Ogura K.,
RA   Otsuka R., Nakazawa H., Takamiya M., Ohfuku Y., Funahashi T., Tanaka T.,
RA   Kudoh Y., Yamazaki J., Kushida N., Oguchi A., Aoki K., Yoshizawa T.,
RA   Nakamura Y., Robb F.T., Horikoshi K., Masuchi Y., Shizuya H., Kikuchi H.;
RT   "Complete sequence and gene organization of the genome of a hyper-
RT   thermophilic archaebacterium, Pyrococcus horikoshii OT3.";
RL   DNA Res. 5:55-76(1998).
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Single-pass membrane
CC       protein {ECO:0000305}.
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DR   EMBL; BA000001; BAA29703.1; -; Genomic_DNA.
DR   PIR; E71105; E71105.
DR   RefSeq; WP_010884713.1; NC_000961.1.
DR   AlphaFoldDB; O58348; -.
DR   SMR; O58348; -.
DR   STRING; 70601.3257020; -.
DR   EnsemblBacteria; BAA29703; BAA29703; BAA29703.
DR   GeneID; 1442947; -.
DR   KEGG; pho:PH0614; -.
DR   eggNOG; arCOG00395; Archaea.
DR   OMA; LIIVRND; -.
DR   OrthoDB; 46782at2157; -.
DR   Proteomes; UP000000752; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR   CDD; cd00090; HTH_ARSR; 1.
DR   Gene3D; 1.10.10.10; -; 1.
DR   InterPro; IPR011991; ArsR-like_HTH.
DR   InterPro; IPR007253; Cell_wall-bd_2.
DR   InterPro; IPR000835; HTH_MarR-typ.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   InterPro; IPR036390; WH_DNA-bd_sf.
DR   Pfam; PF04122; CW_binding_2; 1.
DR   Pfam; PF12802; MarR_2; 1.
DR   SUPFAM; SSF46785; SSF46785; 1.
PE   3: Inferred from homology;
KW   Membrane; Signal; Transmembrane; Transmembrane helix.
FT   SIGNAL          1..23
FT                   /evidence="ECO:0000255"
FT   CHAIN           24..332
FT                   /note="Uncharacterized protein PH0614"
FT                   /id="PRO_0000014218"
FT   TRANSMEM        231..251
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   332 AA;  37363 MW;  8FDE490BFEABEB19 CRC64;
     MKRIPSLIIG LLLILATWHS VLAINDNYDL IIVRNDDLID YLISLPYSHL INAPILPVNP
     KELDPVTKAQ LYSYIQLGRD KVLIIGNTNA VSLDVEKELR DMGFSVTRIG GADRAETAEK
     LALHFYQNGS KVVILASAWD YGSTLAAAEF AMEYKCPILL TWENQLSPSA LRGIEKLNAK
     IVILVGFGIN ETIEKTLEGM GYETYWIGRD IEPPPIETTT SSPPQSSGSK SFFLGMIVTL
     IILAPVILYL WRRRSERMSE FLEQFNEKEL AVLKAIMERG GEVKQEDLPR IVGYSRPTIS
     RIVQDLEKKG IVEREKSGKT FIVRVIKKIK ID