Y614_RHIME
ID Y614_RHIME Reviewed; 408 AA.
AC Q92VT5;
DT 02-MAY-2002, integrated into UniProtKB/Swiss-Prot.
DT 02-MAY-2002, sequence version 2.
DT 03-AUG-2022, entry version 109.
DE RecName: Full=Peptidase T-like protein RB0614;
DE EC=3.4.11.-;
GN OrderedLocusNames=RB0614; ORFNames=SMb21042;
OS Rhizobium meliloti (strain 1021) (Ensifer meliloti) (Sinorhizobium
OS meliloti).
OG Plasmid pSymB (megaplasmid 2).
OC Bacteria; Proteobacteria; Alphaproteobacteria; Hyphomicrobiales;
OC Rhizobiaceae; Sinorhizobium/Ensifer group; Sinorhizobium.
OX NCBI_TaxID=266834;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=1021;
RX PubMed=11481431; DOI=10.1073/pnas.161294698;
RA Finan T.M., Weidner S., Wong K., Buhrmester J., Chain P., Vorhoelter F.J.,
RA Hernandez-Lucas I., Becker A., Cowie A., Gouzy J., Golding B., Puehler A.;
RT "The complete sequence of the 1,683-kb pSymB megaplasmid from the N2-fixing
RT endosymbiont Sinorhizobium meliloti.";
RL Proc. Natl. Acad. Sci. U.S.A. 98:9889-9894(2001).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=1021;
RX PubMed=11474104; DOI=10.1126/science.1060966;
RA Galibert F., Finan T.M., Long S.R., Puehler A., Abola P., Ampe F.,
RA Barloy-Hubler F., Barnett M.J., Becker A., Boistard P., Bothe G.,
RA Boutry M., Bowser L., Buhrmester J., Cadieu E., Capela D., Chain P.,
RA Cowie A., Davis R.W., Dreano S., Federspiel N.A., Fisher R.F., Gloux S.,
RA Godrie T., Goffeau A., Golding B., Gouzy J., Gurjal M., Hernandez-Lucas I.,
RA Hong A., Huizar L., Hyman R.W., Jones T., Kahn D., Kahn M.L., Kalman S.,
RA Keating D.H., Kiss E., Komp C., Lelaure V., Masuy D., Palm C., Peck M.C.,
RA Pohl T.M., Portetelle D., Purnelle B., Ramsperger U., Surzycki R.,
RA Thebault P., Vandenbol M., Vorhoelter F.J., Weidner S., Wells D.H.,
RA Wong K., Yeh K.-C., Batut J.;
RT "The composite genome of the legume symbiont Sinorhizobium meliloti.";
RL Science 293:668-672(2001).
CC -!- COFACTOR:
CC Name=Zn(2+); Xref=ChEBI:CHEBI:29105; Evidence={ECO:0000250};
CC Note=Binds 2 Zn(2+) ions per subunit. {ECO:0000250};
CC -!- SIMILARITY: Belongs to the peptidase M20B family. {ECO:0000305}.
CC -!- SEQUENCE CAUTION:
CC Sequence=CAC49014.1; Type=Erroneous initiation; Evidence={ECO:0000305};
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DR EMBL; AL591985; CAC49014.1; ALT_INIT; Genomic_DNA.
DR PIR; F95918; F95918.
DR RefSeq; NP_437154.1; NC_003078.1.
DR RefSeq; WP_041170089.1; NC_003078.1.
DR AlphaFoldDB; Q92VT5; -.
DR SMR; Q92VT5; -.
DR STRING; 266834.SM_b21042; -.
DR EnsemblBacteria; CAC49014; CAC49014; SM_b21042.
DR GeneID; 61600605; -.
DR KEGG; sme:SM_b21042; -.
DR PATRIC; fig|266834.11.peg.5544; -.
DR eggNOG; COG2195; Bacteria.
DR HOGENOM; CLU_053676_0_0_5; -.
DR Proteomes; UP000001976; Plasmid pSymB.
DR GO; GO:0008237; F:metallopeptidase activity; IEA:UniProtKB-KW.
DR GO; GO:0045148; F:tripeptide aminopeptidase activity; IEA:InterPro.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR GO; GO:0006518; P:peptide metabolic process; IEA:InterPro.
DR GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR InterPro; IPR001261; ArgE/DapE_CS.
DR InterPro; IPR036264; Bact_exopeptidase_dim_dom.
DR InterPro; IPR002933; Peptidase_M20.
DR InterPro; IPR011650; Peptidase_M20_dimer.
DR InterPro; IPR010161; Peptidase_M20B.
DR PANTHER; PTHR42994:SF1; PTHR42994:SF1; 1.
DR Pfam; PF07687; M20_dimer; 1.
DR Pfam; PF01546; Peptidase_M20; 1.
DR PIRSF; PIRSF037215; Peptidase_M20B; 1.
DR SUPFAM; SSF55031; SSF55031; 1.
DR TIGRFAMs; TIGR01882; peptidase-T; 1.
DR PROSITE; PS00758; ARGE_DAPE_CPG2_1; 1.
DR PROSITE; PS00759; ARGE_DAPE_CPG2_2; 1.
PE 3: Inferred from homology;
KW Hydrolase; Metal-binding; Metalloprotease; Plasmid; Protease;
KW Reference proteome; Zinc.
FT CHAIN 1..408
FT /note="Peptidase T-like protein RB0614"
FT /id="PRO_0000185336"
FT ACT_SITE 82
FT /evidence="ECO:0000250"
FT ACT_SITE 174
FT /note="Proton acceptor"
FT /evidence="ECO:0000250"
FT BINDING 80
FT /ligand="Zn(2+)"
FT /ligand_id="ChEBI:CHEBI:29105"
FT /ligand_label="1"
FT /evidence="ECO:0000250"
FT BINDING 142
FT /ligand="Zn(2+)"
FT /ligand_id="ChEBI:CHEBI:29105"
FT /ligand_label="1"
FT /evidence="ECO:0000250"
FT BINDING 142
FT /ligand="Zn(2+)"
FT /ligand_id="ChEBI:CHEBI:29105"
FT /ligand_label="2"
FT /evidence="ECO:0000250"
FT BINDING 175
FT /ligand="Zn(2+)"
FT /ligand_id="ChEBI:CHEBI:29105"
FT /ligand_label="2"
FT /evidence="ECO:0000250"
FT BINDING 198
FT /ligand="Zn(2+)"
FT /ligand_id="ChEBI:CHEBI:29105"
FT /ligand_label="1"
FT /evidence="ECO:0000250"
FT BINDING 380
FT /ligand="Zn(2+)"
FT /ligand_id="ChEBI:CHEBI:29105"
FT /ligand_label="2"
FT /evidence="ECO:0000250"
SQ SEQUENCE 408 AA; 44872 MW; EBBA820F1AA5EA46 CRC64;
MRVREELVSR FFRYAAIESQ SNGRSQSLPS SPGQAALAAL LADEMRAIGL EDVCIDAHAI
VTGVKRGNRP AAPPIGFIAH LDTVDVGLSP FVRPQVLRFE GEDLCINRQE DIWLRVAEHP
EILDWLGEDI IVGDGTSVLG ADNKAAIAVI MTLLGRLDHE VGHGDVFVAF VPDEEIGMRG
AKAMDVSRFP CDFAYTIDCC ELGEVVLETF NAASCEIVFT GVSAHPMSAK GMLVNPLLMA
MDFISHFDRK ETPECTEGRD GFYWFKDLIA NDSVASLTAL IRDFDTDGFN RRKHRIAAVA
EQMRSRYPTG NVRYQITDTY RNVSTSLARD ERAVALLFKA MEELGIGKKV IAMRGGTDGA
VLSAKGIPTP NFFTGAYNFH SRYEFLPVPA FERSLEVALK VCQLAATE
