ID   Y616_RICFE              Reviewed;         331 AA.
AC   Q4ULV6;
DT   06-MAR-2007, integrated into UniProtKB/Swiss-Prot.
DT   05-JUL-2005, sequence version 1.
DT   25-MAY-2022, entry version 75.
DE   RecName: Full=Putative peptidyl-prolyl cis-trans isomerase RF_0616;
DE            Short=PPIase RF_0616;
DE            EC=5.2.1.8;
DE   AltName: Full=Rotamase RF_0616;
GN   OrderedLocusNames=RF_0616;
OS   Rickettsia felis (strain ATCC VR-1525 / URRWXCal2) (Rickettsia azadi).
OC   Bacteria; Proteobacteria; Alphaproteobacteria; Rickettsiales;
OC   Rickettsiaceae; Rickettsieae; Rickettsia; spotted fever group.
OX   NCBI_TaxID=315456;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC VR-1525 / URRWXCal2;
RX   PubMed=15984913; DOI=10.1371/journal.pbio.0030248;
RA   Ogata H., Renesto P., Audic S., Robert C., Blanc G., Fournier P.-E.,
RA   Parinello H., Claverie J.-M., Raoult D.;
RT   "The genome sequence of Rickettsia felis identifies the first putative
RT   conjugative plasmid in an obligate intracellular parasite.";
RL   PLoS Biol. 3:1-12(2005).
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=[protein]-peptidylproline (omega=180) = [protein]-
CC         peptidylproline (omega=0); Xref=Rhea:RHEA:16237, Rhea:RHEA-
CC         COMP:10747, Rhea:RHEA-COMP:10748, ChEBI:CHEBI:83833,
CC         ChEBI:CHEBI:83834; EC=5.2.1.8;
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DR   EMBL; CP000053; AAY61467.1; -; Genomic_DNA.
DR   RefSeq; WP_011270946.1; NC_007109.1.
DR   AlphaFoldDB; Q4ULV6; -.
DR   SMR; Q4ULV6; -.
DR   STRING; 315456.RF_0616; -.
DR   EnsemblBacteria; AAY61467; AAY61467; RF_0616.
DR   KEGG; rfe:RF_0616; -.
DR   eggNOG; COG0545; Bacteria.
DR   HOGENOM; CLU_839076_0_0_5; -.
DR   OMA; TISYRIT; -.
DR   OrthoDB; 568222at2; -.
DR   Proteomes; UP000008548; Chromosome.
DR   GO; GO:0003755; F:peptidyl-prolyl cis-trans isomerase activity; IEA:UniProtKB-KW.
DR   Gene3D; 3.10.50.40; -; 1.
DR   InterPro; IPR046357; PPIase_dom_sf.
DR   InterPro; IPR001179; PPIase_FKBP_dom.
DR   Pfam; PF00254; FKBP_C; 1.
DR   PROSITE; PS50059; FKBP_PPIASE; 1.
PE   4: Predicted;
KW   Isomerase; Rotamase.
FT   CHAIN           1..331
FT                   /note="Putative peptidyl-prolyl cis-trans isomerase
FT                   RF_0616"
FT                   /id="PRO_0000279682"
FT   DOMAIN          128..226
FT                   /note="PPIase FKBP-type"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00277"
FT   REGION          28..50
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   331 AA;  36685 MW;  48A4E8FC93C6287E CRC64;
     MQKFLSLIIV ILILYNIVKL KISPDNNNPT TIEQTASNNS STDENQTSIN NEPHISLNGN
     LFERTVSKIV INALKTEEGK AFFENILQPL NGPINPNDYT IEVRKDLVKT LFKINTLGSG
     NIGPASCGHV VTVFYQISDM NNTLISEDTK TFTLGSAPVM LGLDNVIIGM MVGEAREAII
     PAKYAVNNSK NIIFDDAYNY KVNVILKSIL PQNFVKNNEV KIYDDEIAYR VPLLCGEKVS
     FNAKITRLSN GKILYDSKAK GQQIDMKIGD ITYPLIFSYA LQGKVTVGTR SVIAEGKTFK
     ALGSNINKII SHESLPINEY LLLELGDFKQ N