ID   Y620_METKA              Reviewed;         346 AA.
AC   Q8TXP1;
DT   01-MAY-2007, integrated into UniProtKB/Swiss-Prot.
DT   01-JUN-2002, sequence version 1.
DT   25-MAY-2022, entry version 85.
DE   RecName: Full=UPF0425 pyridoxal phosphate-dependent protein MK0620;
GN   OrderedLocusNames=MK0620;
OS   Methanopyrus kandleri (strain AV19 / DSM 6324 / JCM 9639 / NBRC 100938).
OC   Archaea; Euryarchaeota; Methanopyri; Methanopyrales; Methanopyraceae;
OC   Methanopyrus.
OX   NCBI_TaxID=190192;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=AV19 / DSM 6324 / JCM 9639 / NBRC 100938;
RX   PubMed=11930014; DOI=10.1073/pnas.032671499;
RA   Slesarev A.I., Mezhevaya K.V., Makarova K.S., Polushin N.N.,
RA   Shcherbinina O.V., Shakhova V.V., Belova G.I., Aravind L., Natale D.A.,
RA   Rogozin I.B., Tatusov R.L., Wolf Y.I., Stetter K.O., Malykh A.G.,
RA   Koonin E.V., Kozyavkin S.A.;
RT   "The complete genome of hyperthermophile Methanopyrus kandleri AV19 and
RT   monophyly of archaeal methanogens.";
RL   Proc. Natl. Acad. Sci. U.S.A. 99:4644-4649(2002).
CC   -!- COFACTOR:
CC       Name=pyridoxal 5'-phosphate; Xref=ChEBI:CHEBI:597326;
CC         Evidence={ECO:0000250};
CC   -!- CAUTION: Despite a certain similarity to selA, this is not selA (see AC
CC       Q57622). {ECO:0000305}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; AE009439; AAM01835.1; -; Genomic_DNA.
DR   AlphaFoldDB; Q8TXP1; -.
DR   SMR; Q8TXP1; -.
DR   STRING; 190192.MK0620; -.
DR   EnsemblBacteria; AAM01835; AAM01835; MK0620.
DR   KEGG; mka:MK0620; -.
DR   PATRIC; fig|190192.8.peg.658; -.
DR   HOGENOM; CLU_055443_0_0_2; -.
DR   OMA; RIDFCSK; -.
DR   Proteomes; UP000001826; Chromosome.
DR   GO; GO:0003824; F:catalytic activity; IEA:InterPro.
DR   Gene3D; 3.40.640.10; -; 1.
DR   InterPro; IPR020033; PyrdxlP-dep_transferase_arc.
DR   InterPro; IPR015424; PyrdxlP-dep_Trfase.
DR   InterPro; IPR015421; PyrdxlP-dep_Trfase_major.
DR   SUPFAM; SSF53383; SSF53383; 1.
DR   TIGRFAMs; TIGR03576; pyridox_MJ0158; 1.
PE   3: Inferred from homology;
KW   Pyridoxal phosphate; Reference proteome.
FT   CHAIN           1..346
FT                   /note="UPF0425 pyridoxal phosphate-dependent protein
FT                   MK0620"
FT                   /id="PRO_0000285291"
FT   MOD_RES         206
FT                   /note="N6-(pyridoxal phosphate)lysine"
FT                   /evidence="ECO:0000250"
SQ   SEQUENCE   346 AA;  38637 MW;  AC32C8DBB3DC229D CRC64;
     MRDIGSQPAA GVRSMKVRDR ALEIIRERIS RGDPLYDFTG LASRPKVDAA SDELRTYLSE
     ALILPEIREL CREHFDAPEY EVLVAPRTTA AVIATILALE PRSVLHVLPE DGEAHPCVEE
     GCRLAGAEYE EVEESEIPDL DGFDLVVVTG CDVRWNVVSE DTLREVASAE AVTLLDDASG
     DRVRRLHGQK PGPRYGFDLV VTSCDKLMDG PRAGVLIGRD DLVEGVRRVC EGYGWTVDGP
     TLAAVKRAFE EFELSSLEAR LKELERVYER LKDELDVERT GAGLVFHGVE REVEIGLGLL
     RRYGIMTITA LGYERVDRTL RFNLLTEDAE RFGYDRFVEV VKGELS