ID   Y6251_DICDI             Reviewed;         337 AA.
AC   Q54NZ2;
DT   23-SEP-2008, integrated into UniProtKB/Swiss-Prot.
DT   24-MAY-2005, sequence version 1.
DT   25-MAY-2022, entry version 56.
DE   RecName: Full=Uncharacterized transmembrane protein DDB_G0284909;
GN   ORFNames=DDB_G0284909;
OS   Dictyostelium discoideum (Slime mold).
OC   Eukaryota; Amoebozoa; Evosea; Eumycetozoa; Dictyostelia; Dictyosteliales;
OC   Dictyosteliaceae; Dictyostelium.
OX   NCBI_TaxID=44689;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=AX4;
RX   PubMed=15875012; DOI=10.1038/nature03481;
RA   Eichinger L., Pachebat J.A., Gloeckner G., Rajandream M.A., Sucgang R.,
RA   Berriman M., Song J., Olsen R., Szafranski K., Xu Q., Tunggal B.,
RA   Kummerfeld S., Madera M., Konfortov B.A., Rivero F., Bankier A.T.,
RA   Lehmann R., Hamlin N., Davies R., Gaudet P., Fey P., Pilcher K., Chen G.,
RA   Saunders D., Sodergren E.J., Davis P., Kerhornou A., Nie X., Hall N.,
RA   Anjard C., Hemphill L., Bason N., Farbrother P., Desany B., Just E.,
RA   Morio T., Rost R., Churcher C.M., Cooper J., Haydock S., van Driessche N.,
RA   Cronin A., Goodhead I., Muzny D.M., Mourier T., Pain A., Lu M., Harper D.,
RA   Lindsay R., Hauser H., James K.D., Quiles M., Madan Babu M., Saito T.,
RA   Buchrieser C., Wardroper A., Felder M., Thangavelu M., Johnson D.,
RA   Knights A., Loulseged H., Mungall K.L., Oliver K., Price C., Quail M.A.,
RA   Urushihara H., Hernandez J., Rabbinowitsch E., Steffen D., Sanders M.,
RA   Ma J., Kohara Y., Sharp S., Simmonds M.N., Spiegler S., Tivey A.,
RA   Sugano S., White B., Walker D., Woodward J.R., Winckler T., Tanaka Y.,
RA   Shaulsky G., Schleicher M., Weinstock G.M., Rosenthal A., Cox E.C.,
RA   Chisholm R.L., Gibbs R.A., Loomis W.F., Platzer M., Kay R.R.,
RA   Williams J.G., Dear P.H., Noegel A.A., Barrell B.G., Kuspa A.;
RT   "The genome of the social amoeba Dictyostelium discoideum.";
RL   Nature 435:43-57(2005).
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Multi-pass membrane
CC       protein {ECO:0000305}.
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DR   EMBL; AAFI02000073; EAL64918.1; -; Genomic_DNA.
DR   RefSeq; XP_639925.1; XM_634833.1.
DR   AlphaFoldDB; Q54NZ2; -.
DR   SMR; Q54NZ2; -.
DR   STRING; 44689.DDB0186251; -.
DR   PaxDb; Q54NZ2; -.
DR   EnsemblProtists; EAL64918; EAL64918; DDB_G0284909.
DR   GeneID; 8624837; -.
DR   KEGG; ddi:DDB_G0284909; -.
DR   dictyBase; DDB_G0284909; -.
DR   eggNOG; ENOG502RIIS; Eukaryota.
DR   HOGENOM; CLU_824939_0_0_1; -.
DR   InParanoid; Q54NZ2; -.
DR   OMA; YEFREMI; -.
DR   PRO; PR:Q54NZ2; -.
DR   Proteomes; UP000002195; Chromosome 4.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
PE   4: Predicted;
KW   Membrane; Reference proteome; Transmembrane; Transmembrane helix.
FT   CHAIN           1..337
FT                   /note="Uncharacterized transmembrane protein DDB_G0284909"
FT                   /id="PRO_0000350789"
FT   TOPO_DOM        1..10
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        11..31
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        32..100
FT                   /note="Extracellular"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        101..121
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        122..197
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        198..218
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        219..285
FT                   /note="Extracellular"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        286..306
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        307..337
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
FT   REGION          148..179
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        148..168
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   337 AA;  38858 MW;  CA98C27CC405EC46 CRC64;
     MKLKINIRPN EIIFLICIVV IFSFSYTLTY FDSPIFKEHY ITNNGNDFGV ENHFVTYHST
     YKEDIHKRII DPHHGLIQEI TKTFYPVSSP LEKLFSFSDN ILIVLIIVQV IVGFLIFLLS
     VEKLSKCNYQ LKSIFSTKST FYINNNNNNN NEDINNNNNN NNNNNNKNKN DERNNEEIED
     EETIRKEKIL IIKKKRDILL AIIIFFLVLL GVLTIIYVSF IPLNIRKAFI GQQFYYKGSI
     DPLCADISNE GDHHIGKCKS LNGRIGNVND KIFGYSWSLD SGLFNVKIVF FSTILIEFLT
     GCLILLMKFK KDPNIVPLTK PSIASPTQIP HLFCIAK