Y625_MYCTO
ID Y625_MYCTO Reviewed; 246 AA.
AC P9WFS4; L0T4E5; P67115; P96915;
DT 16-APR-2014, integrated into UniProtKB/Swiss-Prot.
DT 16-APR-2014, sequence version 1.
DT 25-MAY-2022, entry version 29.
DE RecName: Full=TVP38/TMEM64 family membrane protein MT0653;
GN OrderedLocusNames=MT0653;
OS Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh).
OC Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
OC Mycobacterium; Mycobacterium tuberculosis complex.
OX NCBI_TaxID=83331;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CDC 1551 / Oshkosh;
RX PubMed=12218036; DOI=10.1128/jb.184.19.5479-5490.2002;
RA Fleischmann R.D., Alland D., Eisen J.A., Carpenter L., White O.,
RA Peterson J.D., DeBoy R.T., Dodson R.J., Gwinn M.L., Haft D.H., Hickey E.K.,
RA Kolonay J.F., Nelson W.C., Umayam L.A., Ermolaeva M.D., Salzberg S.L.,
RA Delcher A., Utterback T.R., Weidman J.F., Khouri H.M., Gill J., Mikula A.,
RA Bishai W., Jacobs W.R. Jr., Venter J.C., Fraser C.M.;
RT "Whole-genome comparison of Mycobacterium tuberculosis clinical and
RT laboratory strains.";
RL J. Bacteriol. 184:5479-5490(2002).
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Multi-pass membrane
CC protein {ECO:0000305}.
CC -!- SIMILARITY: Belongs to the TVP38/TMEM64 family. {ECO:0000305}.
CC -!- SEQUENCE CAUTION:
CC Sequence=AAK44877.1; Type=Erroneous initiation; Evidence={ECO:0000305};
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DR EMBL; AE000516; AAK44877.1; ALT_INIT; Genomic_DNA.
DR PIR; F70611; F70611.
DR RefSeq; WP_003403239.1; NZ_KK341227.1.
DR AlphaFoldDB; P9WFS4; -.
DR EnsemblBacteria; AAK44877; AAK44877; MT0653.
DR KEGG; mtc:MT0653; -.
DR PATRIC; fig|83331.31.peg.693; -.
DR HOGENOM; CLU_038944_4_2_11; -.
DR Proteomes; UP000001020; Chromosome.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR InterPro; IPR032816; SNARE_assoc.
DR InterPro; IPR015414; TMEM64.
DR PANTHER; PTHR12677; PTHR12677; 1.
DR Pfam; PF09335; SNARE_assoc; 1.
PE 3: Inferred from homology;
KW Cell membrane; Membrane; Transmembrane; Transmembrane helix.
FT CHAIN 1..246
FT /note="TVP38/TMEM64 family membrane protein MT0653"
FT /id="PRO_0000428486"
FT TRANSMEM 19..39
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 57..77
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 83..103
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 157..177
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 196..216
FT /note="Helical"
FT /evidence="ECO:0000255"
SQ SEQUENCE 246 AA; 25212 MW; 61B5CF73E4E15CBB CRC64;
MSTHNDSAPT SRRRHIVRLV VFAGFLVGMF YLVAATDVID VAAVRGAVSA TGPAAPLTYV
VVSAVLGALF VPGPILAASS GLLFGPLVGV FVTLGATVGT AVVASLVGRR AGRASARALL
GGERADRTDA LIERCGLWAV VGQRFVPGIS DAFASYAFGT FGVPLWQMAV GAFIGSAPRA
FAYTALGAAI GDRSPLLASC AIAVWCVTAI IGAFAARHGY RQWRAHARGD GADGGVEDPD
REVGAR