ID   Y628_MYCTU              Reviewed;         383 AA.
AC   P9WKS7; L0T611; P64729; P96918;
DT   16-APR-2014, integrated into UniProtKB/Swiss-Prot.
DT   16-APR-2014, sequence version 1.
DT   25-MAY-2022, entry version 32.
DE   RecName: Full=Uncharacterized protein Rv0628c;
GN   OrderedLocusNames=Rv0628c; ORFNames=MTCY20H10.09c;
OS   Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv).
OC   Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
OC   Mycobacterium; Mycobacterium tuberculosis complex.
OX   NCBI_TaxID=83332;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 25618 / H37Rv;
RX   PubMed=9634230; DOI=10.1038/31159;
RA   Cole S.T., Brosch R., Parkhill J., Garnier T., Churcher C.M., Harris D.E.,
RA   Gordon S.V., Eiglmeier K., Gas S., Barry C.E. III, Tekaia F., Badcock K.,
RA   Basham D., Brown D., Chillingworth T., Connor R., Davies R.M., Devlin K.,
RA   Feltwell T., Gentles S., Hamlin N., Holroyd S., Hornsby T., Jagels K.,
RA   Krogh A., McLean J., Moule S., Murphy L.D., Oliver S., Osborne J.,
RA   Quail M.A., Rajandream M.A., Rogers J., Rutter S., Seeger K., Skelton S.,
RA   Squares S., Squares R., Sulston J.E., Taylor K., Whitehead S.,
RA   Barrell B.G.;
RT   "Deciphering the biology of Mycobacterium tuberculosis from the complete
RT   genome sequence.";
RL   Nature 393:537-544(1998).
RN   [2]
RP   IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RC   STRAIN=ATCC 25618 / H37Rv;
RX   PubMed=21969609; DOI=10.1074/mcp.m111.011627;
RA   Kelkar D.S., Kumar D., Kumar P., Balakrishnan L., Muthusamy B., Yadav A.K.,
RA   Shrivastava P., Marimuthu A., Anand S., Sundaram H., Kingsbury R.,
RA   Harsha H.C., Nair B., Prasad T.S., Chauhan D.S., Katoch K., Katoch V.M.,
RA   Kumar P., Chaerkady R., Ramachandran S., Dash D., Pandey A.;
RT   "Proteogenomic analysis of Mycobacterium tuberculosis by high resolution
RT   mass spectrometry.";
RL   Mol. Cell. Proteomics 10:M111.011627-M111.011627(2011).
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Multi-pass membrane
CC       protein {ECO:0000305}.
CC   -!- SIMILARITY: To M.tuberculosis Rv0874c. {ECO:0000305}.
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DR   EMBL; AL123456; CCP43369.1; -; Genomic_DNA.
DR   PIR; A70612; A70612.
DR   RefSeq; NP_215142.1; NC_000962.3.
DR   RefSeq; WP_003403248.1; NZ_NVQJ01000033.1.
DR   AlphaFoldDB; P9WKS7; -.
DR   STRING; 83332.Rv0628c; -.
DR   PaxDb; P9WKS7; -.
DR   DNASU; 887986; -.
DR   GeneID; 887986; -.
DR   KEGG; mtu:Rv0628c; -.
DR   TubercuList; Rv0628c; -.
DR   eggNOG; COG4398; Bacteria.
DR   OMA; SCIGRGP; -.
DR   PhylomeDB; P9WKS7; -.
DR   Proteomes; UP000001584; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   InterPro; IPR019494; FIST_C.
DR   InterPro; IPR013702; FIST_domain_N.
DR   InterPro; IPR016741; UCP018953.
DR   Pfam; PF08495; FIST; 1.
DR   Pfam; PF10442; FIST_C; 1.
DR   PIRSF; PIRSF018953; UCP018953; 1.
DR   SMART; SM00897; FIST; 1.
DR   SMART; SM01204; FIST_C; 1.
PE   1: Evidence at protein level;
KW   Cell membrane; Membrane; Reference proteome; Transmembrane;
KW   Transmembrane helix.
FT   CHAIN           1..383
FT                   /note="Uncharacterized protein Rv0628c"
FT                   /id="PRO_0000103714"
FT   TRANSMEM        49..69
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        347..367
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   383 AA;  39606 MW;  8C3E68C39426A699 CRC64;
     MRIGVGVSTA PDVRRAAAEA AAHAREELAG GTPALAVLLG SRSHTDQAVD LLAAVQASVE
     PAALIGCVAQ GIVAGRHELE NEPAVAVWLA SGPPAETFHL DFVRTGSGAL ITGYRFDRTA
     HDLHLLLPDP YSFPSNLLIE HLNTDLPGTT VVGGVVSGGR RRGDTRLFRD RDVLTSGLVG
     VRLPGAHSVS VVSQGCRPIG EPYIVTGADG AVITELGGRP PLHRLREIVL GMAPDEQELV
     SRGLQIGIVV DEHLAVPGQG DFLIRGLLGA DPTTGAIGIG EVVEVGATVQ FQVRDAAAAD
     KDLRLAVERA AAELPGPPVG GLLFTCNGRG RRMFGVTDHD ASTIEDLLGG IPLAGFFAAG
     EIGPVAGHNA LHGFTASMAL FVD