Y6311_DICDI
ID Y6311_DICDI Reviewed; 1473 AA.
AC Q54LY1;
DT 20-APR-2010, integrated into UniProtKB/Swiss-Prot.
DT 24-MAY-2005, sequence version 1.
DT 25-MAY-2022, entry version 62.
DE RecName: Full=G8 domain-containing protein DDB_G0286311;
DE Flags: Precursor;
GN ORFNames=DDB_G0286311;
OS Dictyostelium discoideum (Slime mold).
OC Eukaryota; Amoebozoa; Evosea; Eumycetozoa; Dictyostelia; Dictyosteliales;
OC Dictyosteliaceae; Dictyostelium.
OX NCBI_TaxID=44689;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=AX4;
RX PubMed=15875012; DOI=10.1038/nature03481;
RA Eichinger L., Pachebat J.A., Gloeckner G., Rajandream M.A., Sucgang R.,
RA Berriman M., Song J., Olsen R., Szafranski K., Xu Q., Tunggal B.,
RA Kummerfeld S., Madera M., Konfortov B.A., Rivero F., Bankier A.T.,
RA Lehmann R., Hamlin N., Davies R., Gaudet P., Fey P., Pilcher K., Chen G.,
RA Saunders D., Sodergren E.J., Davis P., Kerhornou A., Nie X., Hall N.,
RA Anjard C., Hemphill L., Bason N., Farbrother P., Desany B., Just E.,
RA Morio T., Rost R., Churcher C.M., Cooper J., Haydock S., van Driessche N.,
RA Cronin A., Goodhead I., Muzny D.M., Mourier T., Pain A., Lu M., Harper D.,
RA Lindsay R., Hauser H., James K.D., Quiles M., Madan Babu M., Saito T.,
RA Buchrieser C., Wardroper A., Felder M., Thangavelu M., Johnson D.,
RA Knights A., Loulseged H., Mungall K.L., Oliver K., Price C., Quail M.A.,
RA Urushihara H., Hernandez J., Rabbinowitsch E., Steffen D., Sanders M.,
RA Ma J., Kohara Y., Sharp S., Simmonds M.N., Spiegler S., Tivey A.,
RA Sugano S., White B., Walker D., Woodward J.R., Winckler T., Tanaka Y.,
RA Shaulsky G., Schleicher M., Weinstock G.M., Rosenthal A., Cox E.C.,
RA Chisholm R.L., Gibbs R.A., Loomis W.F., Platzer M., Kay R.R.,
RA Williams J.G., Dear P.H., Noegel A.A., Barrell B.G., Kuspa A.;
RT "The genome of the social amoeba Dictyostelium discoideum.";
RL Nature 435:43-57(2005).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Multi-pass membrane
CC protein {ECO:0000305}.
CC -!- SIMILARITY: Belongs to the comF family. {ECO:0000305}.
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DR EMBL; AAFI02000085; EAL64331.1; -; Genomic_DNA.
DR RefSeq; XP_637850.1; XM_632758.1.
DR AlphaFoldDB; Q54LY1; -.
DR PaxDb; Q54LY1; -.
DR EnsemblProtists; EAL64331; EAL64331; DDB_G0286311.
DR GeneID; 8625564; -.
DR KEGG; ddi:DDB_G0286311; -.
DR dictyBase; DDB_G0286311; -.
DR eggNOG; ENOG502QRDD; Eukaryota.
DR HOGENOM; CLU_005143_0_0_1; -.
DR InParanoid; Q54LY1; -.
DR OMA; LMIATIT; -.
DR PhylomeDB; Q54LY1; -.
DR PRO; PR:Q54LY1; -.
DR Proteomes; UP000002195; Chromosome 4.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR InterPro; IPR019316; G8_domain.
DR Pfam; PF10162; G8; 1.
DR SMART; SM01225; G8; 1.
DR PROSITE; PS51484; G8; 1.
PE 3: Inferred from homology;
KW Glycoprotein; Membrane; Reference proteome; Signal; Transmembrane;
KW Transmembrane helix.
FT SIGNAL 1..21
FT /evidence="ECO:0000255"
FT CHAIN 22..1473
FT /note="G8 domain-containing protein DDB_G0286311"
FT /id="PRO_0000393591"
FT TRANSMEM 105..125
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 130..150
FT /note="Helical"
FT /evidence="ECO:0000255"
FT DOMAIN 626..754
FT /note="G8"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00817"
FT REGION 298..400
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT CARBOHYD 126
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 203
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 241
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 275
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 444
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 637
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 680
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 1078
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 1088
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 1176
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 1206
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 1225
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 1389
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 1424
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
SQ SEQUENCE 1473 AA; 161408 MW; 83D9C71313BED26D CRC64;
MKRFFIVILF ILLVCIFNVK SEEQLGEIEI SKNSFSIDTN AINAEINYVI DNSITKPKLI
VTLLSGDVNS IEDITSISKD KSTLTFGDFS SLSLGNKQSN NNNRIVLMIA TITGSLLFIR
FNIGFNKSTT LIILIIGTIF LIGSSHSITL SEVSIRIDIK VPSTFKFEKL DLKLGSGSSN
IIGLSSNSIN IDSCLNLKDH KINLSDTTIT SALNICSTKN IDIKNLKQSS NSLINLKTNS
NITLNFGNGY SGLLDIYSNS LKIDEACDIK VDGLNTTGSC NEGTSSKLVI NANGVTITGT
TPTTTPTTTP TTTPTTTPTT TPTTTPTTTP TTTPTTTPTT TPTTTPTTTP TTTPTTTPTI
TPTTTPTTTP TTTPTDSCPT TSTWRPTMAS SSSPSSPSFS SVTPILDFNF DKSNLGFRSR
YKFNEKSISD GPNGIANSFS INFNETYSPD SNWLISKIPS PALRANVNYV FSFNFKLGQA
LSSDNTISSV TISFYSPIDL PDPNVLEYFD QPTASPLFTK TITTGSFSSS TTFQANSISI
KPTTDIGLSL IAIQIIRTKQ NSIPINLYFS EMKLSIPSKS IIDPTTFLTK DSELINIPKA
SASFDSQDPS TCPYLATDLV HWHDKSIWSS GIVPLPNASS NIILPAGKRV LISPCSISQT
DIYKKITIPP TSELIFSDVN MTMHVQDIYV QGKFTMGTKE CRYNAYINLI FHGTKTTSDT
IATNFGSKGI AVASGGFISV QGKQYHNTWS KLSTTAWSGD STIYIQDSVN WEVGQQVLIT
TSVYKDELYN QNEVLTIAAI SGKKIQFTSA LKYYHYGGQE YQAEVGLLSR RIVFQGDQSS
SDPQQFGGHV LVSGEGQFSG LSLVRFGQKN IKGRYPLHYH LANNVQKSYI SDCSVIDSYY
RCYTIHGTNG VTLTRNVAFN AIGHCYYLED GVEVDNTISY NLGAFVHTIG TPAAGYNQYG
QDFLQSSDLT QPADSAAACY YITNAANSFI GNAASGGWSG FAFPNLPRPI GNHLSVSIVP
SQFIAKVWEG NTAHSSGYYF EFGASIYVGG LLTYNDATGL LQYSSGRESR DTYLTGYNTS
AAVWMRFNNT KVYLSNRGLS MWGERTEAVN LESHDSRRPA SLFGEAWLSN AIVNGQSGNI
LSASVEYTRQ GFQFYDTYVQ TIISNIIFRN FIKYQNASSN EEDNRVIISM THSSEFLPQG
ISVSKNITIQ NTATSQFIGH NIPVNSTGSS RFFNFIDWDG SLTGKNVPTL IGSHEKFWQF
DNTCSFNSDW NCYVCTKGTR EIANVQFWVP GLISRDDAQN NDDSIGSISL FGDGITDRRS
TRVIHTAGIT GVSNSGWYLY LTDGTPTYMK IWLAQVIYNN YLFIAIPYPA TTTFSVSSEY
KYNSNYNFNF TQTSSASAVR SGDGKKYYFD GTHLFIKVIN FRLNGTESFD RGGAKVYDVY
WEFLIHITAS NTIKPPVNGF FKGLTDTLPS SNL
