CASP1_BRADI
ID CASP1_BRADI Reviewed; 231 AA.
AC P0DI38; A0A0Q3H5U0;
DT 13-JUN-2012, integrated into UniProtKB/Swiss-Prot.
DT 13-JUN-2012, sequence version 1.
DT 25-MAY-2022, entry version 37.
DE RecName: Full=Casparian strip membrane protein 1;
DE Short=BdCASP1;
GN OrderedLocusNames=Bradi5g15727; ORFNames=LOC100842918;
OS Brachypodium distachyon (Purple false brome) (Trachynia distachya).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC Pooideae; Stipodae; Brachypodieae; Brachypodium.
OX NCBI_TaxID=15368;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Bd21;
RX PubMed=20148030; DOI=10.1038/nature08747;
RG International Brachypodium Initiative;
RT "Genome sequencing and analysis of the model grass Brachypodium
RT distachyon.";
RL Nature 463:763-768(2010).
RN [2]
RP GENE FAMILY, AND NOMENCLATURE.
RX PubMed=24920445; DOI=10.1104/pp.114.239137;
RA Roppolo D., Boeckmann B., Pfister A., Boutet E., Rubio M.C.,
RA Denervaud-Tendon V., Vermeer J.E., Gheyselinck J., Xenarios I., Geldner N.;
RT "Functional and evolutionary analysis of the CASPARIAN STRIP MEMBRANE
RT DOMAIN PROTEIN family.";
RL Plant Physiol. 165:1709-1722(2014).
CC -!- FUNCTION: Regulates membrane-cell wall junctions and localized cell
CC wall deposition. Required for establishment of the Casparian strip
CC membrane domain (CSD) and the subsequent formation of Casparian strips,
CC a cell wall modification of the root endodermis that determines an
CC apoplastic barrier between the intraorganismal apoplasm and the
CC extraorganismal apoplasm and prevents lateral diffusion (By
CC similarity). {ECO:0000250}.
CC -!- SUBUNIT: Homodimer and heterodimers. {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000250}; Multi-pass membrane
CC protein {ECO:0000250}. Note=Very restricted localization following a
CC belt shape within the plasma membrane which coincides with the position
CC of the Casparian strip membrane domain in the root endodermis.
CC {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the Casparian strip membrane proteins (CASP)
CC family. {ECO:0000305}.
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DR EMBL; CM000884; KQJ83603.1; -; Genomic_DNA.
DR RefSeq; XP_003580136.1; XM_003580088.3.
DR AlphaFoldDB; P0DI38; -.
DR STRING; 15368.BRADI5G15727.1; -.
DR EnsemblPlants; KQJ83603; KQJ83603; BRADI_5g15727v3.
DR GeneID; 100842918; -.
DR Gramene; KQJ83603; KQJ83603; BRADI_5g15727v3.
DR KEGG; bdi:100842918; -.
DR eggNOG; ENOG502QZV7; Eukaryota.
DR HOGENOM; CLU_066104_3_1_1; -.
DR InParanoid; P0DI38; -.
DR OMA; DMIMAAL; -.
DR OrthoDB; 1385348at2759; -.
DR Proteomes; UP000008810; Chromosome 5.
DR GO; GO:0048226; C:Casparian strip; IBA:GO_Central.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0005886; C:plasma membrane; IBA:GO_Central.
DR GO; GO:0051539; F:4 iron, 4 sulfur cluster binding; IBA:GO_Central.
DR GO; GO:0042545; P:cell wall modification; IBA:GO_Central.
DR GO; GO:0007043; P:cell-cell junction assembly; IBA:GO_Central.
DR InterPro; IPR006459; CASP/CASPL.
DR InterPro; IPR006702; CASP_dom.
DR Pfam; PF04535; DUF588; 1.
DR TIGRFAMs; TIGR01569; A_tha_TIGR01569; 1.
PE 3: Inferred from homology;
KW Cell membrane; Cell wall biogenesis/degradation; Membrane;
KW Reference proteome; Transmembrane; Transmembrane helix.
FT CHAIN 1..231
FT /note="Casparian strip membrane protein 1"
FT /id="PRO_0000417764"
FT TOPO_DOM 1..69
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 70..90
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 91..117
FT /note="Extracellular"
FT /evidence="ECO:0000255"
FT TRANSMEM 118..138
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 139..152
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 153..173
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 174..207
FT /note="Extracellular"
FT /evidence="ECO:0000255"
FT TRANSMEM 208..228
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 229..231
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
SQ SEQUENCE 231 AA; 24241 MW; 7165189EE661A687 CRC64;
MSTSETATVI PVYDVAPGQQ GAPAVDRAPA PSAPPAAAAA PAAAAAKSTA PRRFAAGRFF
RQSDRGSRCL AFLDFLLRIA AFGPALAAAI ATGTSDETLS VFTEFFQFRA RFDDFPAFLF
LMVANAIAAG YLVLSLPFSA VVVLRPQATG LRLLLLVCDT IMIGLLTAAA AAAAAIVELA
HNGNERANWV AICMQFHGFC QRTSGAVVAS FLSVFLFLLL VVLAAFAIRK R