ID   Y637_MYCTU              Reviewed;         166 AA.
AC   P9WFJ9; L0T4B1; P96928; Q7D9H8;
DT   16-APR-2014, integrated into UniProtKB/Swiss-Prot.
DT   16-APR-2014, sequence version 1.
DT   03-AUG-2022, entry version 39.
DE   RecName: Full=UPF0336 protein Rv0637 {ECO:0000255|HAMAP-Rule:MF_00799};
GN   OrderedLocusNames=Rv0637; ORFNames=MTCY20H10.18;
OS   Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv).
OC   Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
OC   Mycobacterium; Mycobacterium tuberculosis complex.
OX   NCBI_TaxID=83332;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 25618 / H37Rv;
RX   PubMed=9634230; DOI=10.1038/31159;
RA   Cole S.T., Brosch R., Parkhill J., Garnier T., Churcher C.M., Harris D.E.,
RA   Gordon S.V., Eiglmeier K., Gas S., Barry C.E. III, Tekaia F., Badcock K.,
RA   Basham D., Brown D., Chillingworth T., Connor R., Davies R.M., Devlin K.,
RA   Feltwell T., Gentles S., Hamlin N., Holroyd S., Hornsby T., Jagels K.,
RA   Krogh A., McLean J., Moule S., Murphy L.D., Oliver S., Osborne J.,
RA   Quail M.A., Rajandream M.A., Rogers J., Rutter S., Seeger K., Skelton S.,
RA   Squares S., Squares R., Sulston J.E., Taylor K., Whitehead S.,
RA   Barrell B.G.;
RT   "Deciphering the biology of Mycobacterium tuberculosis from the complete
RT   genome sequence.";
RL   Nature 393:537-544(1998).
RN   [2]
RP   IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RC   STRAIN=ATCC 25618 / H37Rv;
RX   PubMed=21969609; DOI=10.1074/mcp.m111.011627;
RA   Kelkar D.S., Kumar D., Kumar P., Balakrishnan L., Muthusamy B., Yadav A.K.,
RA   Shrivastava P., Marimuthu A., Anand S., Sundaram H., Kingsbury R.,
RA   Harsha H.C., Nair B., Prasad T.S., Chauhan D.S., Katoch K., Katoch V.M.,
RA   Kumar P., Chaerkady R., Ramachandran S., Dash D., Pandey A.;
RT   "Proteogenomic analysis of Mycobacterium tuberculosis by high resolution
RT   mass spectrometry.";
RL   Mol. Cell. Proteomics 10:M111.011627-M111.011627(2011).
CC   -!- INTERACTION:
CC       P9WFJ9; P96927: MT0665; Xeno; NbExp=4; IntAct=EBI-15655983, EBI-15655915;
CC   -!- SIMILARITY: Belongs to the UPF0336 family. {ECO:0000255|HAMAP-
CC       Rule:MF_00799}.
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DR   EMBL; AL123456; CCP43380.1; -; Genomic_DNA.
DR   PIR; B70613; B70613.
DR   RefSeq; NP_215151.1; NC_000962.3.
DR   RefSeq; WP_003403282.1; NZ_NVQJ01000007.1.
DR   PDB; 5ZY8; X-ray; 2.90 A; A/C=1-158.
DR   PDBsum; 5ZY8; -.
DR   AlphaFoldDB; P9WFJ9; -.
DR   SMR; P9WFJ9; -.
DR   IntAct; P9WFJ9; 1.
DR   STRING; 83332.Rv0637; -.
DR   PaxDb; P9WFJ9; -.
DR   DNASU; 888019; -.
DR   GeneID; 45424596; -.
DR   GeneID; 888019; -.
DR   KEGG; mtu:Rv0637; -.
DR   TubercuList; Rv0637; -.
DR   eggNOG; COG2030; Bacteria.
DR   OMA; SISAGWD; -.
DR   PhylomeDB; P9WFJ9; -.
DR   BioCyc; MetaCyc:G185E-4779-MON; -.
DR   BRENDA; 4.2.1.157; 3445.
DR   Proteomes; UP000001584; Chromosome.
DR   GO; GO:0005886; C:plasma membrane; HDA:MTBBASE.
DR   GO; GO:0019171; F:3-hydroxyacyl-[acyl-carrier-protein] dehydratase activity; IDA:MTBBASE.
DR   GO; GO:0006633; P:fatty acid biosynthetic process; IBA:GO_Central.
DR   GO; GO:0030497; P:fatty acid elongation; IDA:MTBBASE.
DR   GO; GO:0042759; P:long-chain fatty acid biosynthetic process; IDA:MTBBASE.
DR   HAMAP; MF_00799; UPF0336; 1.
DR   InterPro; IPR029069; HotDog_dom_sf.
DR   InterPro; IPR039569; MaoC-like_dehydrat_N.
DR   InterPro; IPR016709; UPF0336.
DR   Pfam; PF13452; MaoC_dehydrat_N; 1.
DR   PIRSF; PIRSF018072; UCP018072; 1.
DR   SUPFAM; SSF54637; SSF54637; 1.
PE   1: Evidence at protein level;
KW   3D-structure; Reference proteome.
FT   CHAIN           1..166
FT                   /note="UPF0336 protein Rv0637"
FT                   /id="PRO_0000216144"
FT   STRAND          11..13
FT                   /evidence="ECO:0007829|PDB:5ZY8"
FT   HELIX           22..31
FT                   /evidence="ECO:0007829|PDB:5ZY8"
FT   HELIX           37..39
FT                   /evidence="ECO:0007829|PDB:5ZY8"
FT   HELIX           42..47
FT                   /evidence="ECO:0007829|PDB:5ZY8"
FT   TURN            57..60
FT                   /evidence="ECO:0007829|PDB:5ZY8"
FT   HELIX           61..74
FT                   /evidence="ECO:0007829|PDB:5ZY8"
FT   STRAND          85..95
FT                   /evidence="ECO:0007829|PDB:5ZY8"
FT   STRAND          102..112
FT                   /evidence="ECO:0007829|PDB:5ZY8"
FT   STRAND          121..129
FT                   /evidence="ECO:0007829|PDB:5ZY8"
FT   STRAND          134..143
FT                   /evidence="ECO:0007829|PDB:5ZY8"
SQ   SEQUENCE   166 AA;  18930 MW;  71BE5CF102B02BDA CRC64;
     MALKTDIRGM IWRYPDYFIV GREQCREFAR AVKCDHPAFF SEEAAADLGY DALVAPLTFV
     TILAKYVQLD FFRHVDVGME TMQIVQVDQR FVFHKPVLAG DKLWARMDIH SVDERFGADI
     VVTRNLCTND DGELVMEAYT TLMGQQGDGS ARLKWDKESG QVIRTA