ID   Y639_GEOKA              Reviewed;         377 AA.
AC   Q5L2A6;
DT   03-NOV-2009, integrated into UniProtKB/Swiss-Prot.
DT   01-FEB-2005, sequence version 1.
DT   25-MAY-2022, entry version 60.
DE   RecName: Full=UPF0754 membrane protein GK0639;
GN   OrderedLocusNames=GK0639;
OS   Geobacillus kaustophilus (strain HTA426).
OC   Bacteria; Firmicutes; Bacilli; Bacillales; Bacillaceae; Geobacillus;
OC   Geobacillus thermoleovorans group.
OX   NCBI_TaxID=235909;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=HTA426;
RX   PubMed=15576355; DOI=10.1093/nar/gkh970;
RA   Takami H., Takaki Y., Chee G.-J., Nishi S., Shimamura S., Suzuki H.,
RA   Matsui S., Uchiyama I.;
RT   "Thermoadaptation trait revealed by the genome sequence of thermophilic
RT   Geobacillus kaustophilus.";
RL   Nucleic Acids Res. 32:6292-6303(2004).
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000250}; Multi-pass membrane
CC       protein {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the UPF0754 family. {ECO:0000305}.
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DR   EMBL; BA000043; BAD74924.1; -; Genomic_DNA.
DR   RefSeq; WP_011230143.1; NC_006510.1.
DR   AlphaFoldDB; Q5L2A6; -.
DR   SMR; Q5L2A6; -.
DR   STRING; 235909.GK0639; -.
DR   EnsemblBacteria; BAD74924; BAD74924; GK0639.
DR   KEGG; gka:GK0639; -.
DR   eggNOG; COG4399; Bacteria.
DR   HOGENOM; CLU_042384_0_0_9; -.
DR   OMA; DTIMGSL; -.
DR   Proteomes; UP000001172; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   InterPro; IPR007383; DUF445.
DR   InterPro; IPR016991; UCP032178.
DR   Pfam; PF04286; DUF445; 1.
DR   PIRSF; PIRSF032178; UCP032178; 1.
PE   3: Inferred from homology;
KW   Cell membrane; Membrane; Reference proteome; Transmembrane;
KW   Transmembrane helix.
FT   CHAIN           1..377
FT                   /note="UPF0754 membrane protein GK0639"
FT                   /id="PRO_0000388292"
FT   TRANSMEM        7..27
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        357..377
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   377 AA;  43271 MW;  02C27A4D6759A1F9 CRC64;
     METFVYLLFM VAVGALIGGV TNFIAIVMLF RPYEPMYVFG KRLPFTPGLI PKRRRELAEQ
     LGKTVVEHLV TPEGLRRKLM DPSFTAEMAE WGREWLRKWL ARKETPAELL ERLGIRSPAE
     RLEAMAAEQA ERAYERWSET WRLRPIRDVL PAELKQTMEA RVESLAGYLA DRTLDYFRSE
     EGKQQISSMI ERFFQERGMV GNMLQMLLGN VNFVDKVQAE LGKFLRHAGT REVLSRLLWT
     EWNKWLDYPL ATVEEMIGRR RIDEAVRSAA RRLVQSGSWL HRPLDELIAP YEQPLFDRLI
     PQAAATVSCL LSDKIEAIVA QLGLADIVRD QVESFSLRRL EAIILSIARR ELKMITYLGA
     LLGGLIGAVQ GVIGLWL