ID   Y641_MYCBO              Reviewed;         246 AA.
AC   P67116; A0A1R3XVW7; P96915; X2BFN9;
DT   11-OCT-2004, integrated into UniProtKB/Swiss-Prot.
DT   11-OCT-2004, sequence version 1.
DT   25-MAY-2022, entry version 87.
DE   RecName: Full=TVP38/TMEM64 family membrane protein Mb0641c;
GN   OrderedLocusNames=BQ2027_MB0641C;
OS   Mycobacterium bovis (strain ATCC BAA-935 / AF2122/97).
OC   Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
OC   Mycobacterium; Mycobacterium tuberculosis complex.
OX   NCBI_TaxID=233413;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC BAA-935 / AF2122/97;
RX   PubMed=12788972; DOI=10.1073/pnas.1130426100;
RA   Garnier T., Eiglmeier K., Camus J.-C., Medina N., Mansoor H., Pryor M.,
RA   Duthoy S., Grondin S., Lacroix C., Monsempe C., Simon S., Harris B.,
RA   Atkin R., Doggett J., Mayes R., Keating L., Wheeler P.R., Parkhill J.,
RA   Barrell B.G., Cole S.T., Gordon S.V., Hewinson R.G.;
RT   "The complete genome sequence of Mycobacterium bovis.";
RL   Proc. Natl. Acad. Sci. U.S.A. 100:7877-7882(2003).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA], AND GENOME REANNOTATION.
RC   STRAIN=ATCC BAA-935 / AF2122/97;
RX   PubMed=28385856; DOI=10.1128/genomea.00157-17;
RA   Malone K.M., Farrell D., Stuber T.P., Schubert O.T., Aebersold R.,
RA   Robbe-Austerman S., Gordon S.V.;
RT   "Updated reference genome sequence and annotation of Mycobacterium bovis
RT   AF2122/97.";
RL   Genome Announc. 5:E00157-E00157(2017).
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Multi-pass membrane
CC       protein {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the TVP38/TMEM64 family. {ECO:0000305}.
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DR   EMBL; LT708304; SIT99239.1; -; Genomic_DNA.
DR   RefSeq; NP_854300.1; NC_002945.3.
DR   RefSeq; WP_003403239.1; NC_002945.4.
DR   AlphaFoldDB; P67116; -.
DR   EnsemblBacteria; SIT99239; SIT99239; BQ2027_MB0641C.
DR   PATRIC; fig|233413.5.peg.701; -.
DR   OMA; WCVSAIV; -.
DR   Proteomes; UP000001419; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   InterPro; IPR032816; SNARE_assoc.
DR   InterPro; IPR015414; TMEM64.
DR   PANTHER; PTHR12677; PTHR12677; 1.
DR   Pfam; PF09335; SNARE_assoc; 1.
PE   3: Inferred from homology;
KW   Cell membrane; Membrane; Transmembrane; Transmembrane helix.
FT   CHAIN           1..246
FT                   /note="TVP38/TMEM64 family membrane protein Mb0641c"
FT                   /id="PRO_0000198637"
FT   TRANSMEM        19..39
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        57..77
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        83..103
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        157..177
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        196..216
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   246 AA;  25212 MW;  61B5CF73E4E15CBB CRC64;
     MSTHNDSAPT SRRRHIVRLV VFAGFLVGMF YLVAATDVID VAAVRGAVSA TGPAAPLTYV
     VVSAVLGALF VPGPILAASS GLLFGPLVGV FVTLGATVGT AVVASLVGRR AGRASARALL
     GGERADRTDA LIERCGLWAV VGQRFVPGIS DAFASYAFGT FGVPLWQMAV GAFIGSAPRA
     FAYTALGAAI GDRSPLLASC AIAVWCVTAI IGAFAARHGY RQWRAHARGD GADGGVEDPD
     REVGAR