Y643_LEGPH
ID Y643_LEGPH Reviewed; 412 AA.
AC Q5ZXT8;
DT 09-FEB-2010, integrated into UniProtKB/Swiss-Prot.
DT 23-NOV-2004, sequence version 1.
DT 03-AUG-2022, entry version 86.
DE RecName: Full=UPF0761 membrane protein lpg0643 {ECO:0000255|HAMAP-Rule:MF_00672};
GN OrderedLocusNames=lpg0643;
OS Legionella pneumophila subsp. pneumophila (strain Philadelphia 1 / ATCC
OS 33152 / DSM 7513).
OC Bacteria; Proteobacteria; Gammaproteobacteria; Legionellales;
OC Legionellaceae; Legionella.
OX NCBI_TaxID=272624;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Philadelphia 1 / ATCC 33152 / DSM 7513;
RX PubMed=15448271; DOI=10.1126/science.1099776;
RA Chien M., Morozova I., Shi S., Sheng H., Chen J., Gomez S.M., Asamani G.,
RA Hill K., Nuara J., Feder M., Rineer J., Greenberg J.J., Steshenko V.,
RA Park S.H., Zhao B., Teplitskaya E., Edwards J.R., Pampou S., Georghiou A.,
RA Chou I.-C., Iannuccilli W., Ulz M.E., Kim D.H., Geringer-Sameth A.,
RA Goldsberry C., Morozov P., Fischer S.G., Segal G., Qu X., Rzhetsky A.,
RA Zhang P., Cayanis E., De Jong P.J., Ju J., Kalachikov S., Shuman H.A.,
RA Russo J.J.;
RT "The genomic sequence of the accidental pathogen Legionella pneumophila.";
RL Science 305:1966-1968(2004).
CC -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000255|HAMAP-
CC Rule:MF_00672}; Multi-pass membrane protein {ECO:0000255|HAMAP-
CC Rule:MF_00672}.
CC -!- SIMILARITY: Belongs to the UPF0761 family. {ECO:0000255|HAMAP-
CC Rule:MF_00672}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AE017354; AAU26732.1; -; Genomic_DNA.
DR RefSeq; WP_010946380.1; NC_002942.5.
DR RefSeq; YP_094679.1; NC_002942.5.
DR AlphaFoldDB; Q5ZXT8; -.
DR SMR; Q5ZXT8; -.
DR STRING; 272624.lpg0643; -.
DR PaxDb; Q5ZXT8; -.
DR PRIDE; Q5ZXT8; -.
DR DNASU; 3078458; -.
DR EnsemblBacteria; AAU26732; AAU26732; lpg0643.
DR GeneID; 66489832; -.
DR KEGG; lpn:lpg0643; -.
DR PATRIC; fig|272624.6.peg.661; -.
DR eggNOG; COG1295; Bacteria.
DR HOGENOM; CLU_032288_1_0_6; -.
DR OMA; LYWTVLT; -.
DR Proteomes; UP000000609; Chromosome.
DR GO; GO:0005887; C:integral component of plasma membrane; IEA:UniProtKB-UniRule.
DR HAMAP; MF_00672; UPF0761; 1.
DR InterPro; IPR023679; UPF0761_bac.
DR InterPro; IPR017039; Virul_fac_BrkB.
DR PANTHER; PTHR30213; PTHR30213; 1.
DR Pfam; PF03631; Virul_fac_BrkB; 1.
DR TIGRFAMs; TIGR00765; yihY_not_rbn; 1.
PE 3: Inferred from homology;
KW Cell inner membrane; Cell membrane; Membrane; Reference proteome;
KW Transmembrane; Transmembrane helix.
FT CHAIN 1..412
FT /note="UPF0761 membrane protein lpg0643"
FT /id="PRO_0000391039"
FT TRANSMEM 36..56
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_00672"
FT TRANSMEM 99..119
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_00672"
FT TRANSMEM 137..157
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_00672"
FT TRANSMEM 177..197
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_00672"
FT TRANSMEM 210..230
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_00672"
FT TRANSMEM 241..261
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_00672"
SQ SEQUENCE 412 AA; 47068 MW; ED1752AACCF6CA4F CRC64;
MNWKDKVKTT FYSCDRFVRF VIQHFIQDDC TYIASALAFT SLLAVVPLMS VGLAIFSSFP
VFQGLAEPVQ NFIFDNFVPA TGKIVQSYLQ QFTSQVSKLS IWGIVFLIFT ALLVMFTIER
AMNKIWRVSS SRHGVSAFLL YWAIISLAPV LLGLSLAASS YLFSMPILAD HRAPYTILHY
SPFFLSLIGF TFLYVVVPNC PVKIRHAFWG GLVAAILFES AKHAFAYYLI RYNTYALLYG
AFATVPIFFI WVYWVWIITL LGAEISYAFS VHHQRRGGKS LDGFSHALLW LHQLWLAQQH
GKGLSFNDLV DASKQPFAVD VDEMINALIY HELIHATADG HYMLSRDLSH VTLYDLTQLL
PYRLPTHLEL QYSKASLAEQ WRAAFKRHNE ELKKSLDINL EELFKKTGTV IK
