ID   Y644_MYCBO              Reviewed;         383 AA.
AC   P64730; A0A1R3XY22; P96918; X2BFF5;
DT   11-OCT-2004, integrated into UniProtKB/Swiss-Prot.
DT   11-OCT-2004, sequence version 1.
DT   25-MAY-2022, entry version 89.
DE   RecName: Full=Uncharacterized protein Mb0644c;
GN   OrderedLocusNames=BQ2027_MB0644C;
OS   Mycobacterium bovis (strain ATCC BAA-935 / AF2122/97).
OC   Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
OC   Mycobacterium; Mycobacterium tuberculosis complex.
OX   NCBI_TaxID=233413;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC BAA-935 / AF2122/97;
RX   PubMed=12788972; DOI=10.1073/pnas.1130426100;
RA   Garnier T., Eiglmeier K., Camus J.-C., Medina N., Mansoor H., Pryor M.,
RA   Duthoy S., Grondin S., Lacroix C., Monsempe C., Simon S., Harris B.,
RA   Atkin R., Doggett J., Mayes R., Keating L., Wheeler P.R., Parkhill J.,
RA   Barrell B.G., Cole S.T., Gordon S.V., Hewinson R.G.;
RT   "The complete genome sequence of Mycobacterium bovis.";
RL   Proc. Natl. Acad. Sci. U.S.A. 100:7877-7882(2003).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA], AND GENOME REANNOTATION.
RC   STRAIN=ATCC BAA-935 / AF2122/97;
RX   PubMed=28385856; DOI=10.1128/genomea.00157-17;
RA   Malone K.M., Farrell D., Stuber T.P., Schubert O.T., Aebersold R.,
RA   Robbe-Austerman S., Gordon S.V.;
RT   "Updated reference genome sequence and annotation of Mycobacterium bovis
RT   AF2122/97.";
RL   Genome Announc. 5:E00157-E00157(2017).
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Multi-pass membrane
CC       protein {ECO:0000305}.
CC   -!- SIMILARITY: To M.tuberculosis Rv0874c. {ECO:0000305}.
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DR   EMBL; LT708304; SIT99242.1; -; Genomic_DNA.
DR   RefSeq; NP_854303.1; NC_002945.3.
DR   RefSeq; WP_003403248.1; NC_002945.4.
DR   AlphaFoldDB; P64730; -.
DR   EnsemblBacteria; SIT99242; SIT99242; BQ2027_MB0644C.
DR   PATRIC; fig|233413.5.peg.704; -.
DR   OMA; SCIGRGP; -.
DR   Proteomes; UP000001419; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   InterPro; IPR019494; FIST_C.
DR   InterPro; IPR013702; FIST_domain_N.
DR   InterPro; IPR016741; UCP018953.
DR   Pfam; PF08495; FIST; 1.
DR   Pfam; PF10442; FIST_C; 1.
DR   PIRSF; PIRSF018953; UCP018953; 1.
DR   SMART; SM00897; FIST; 1.
DR   SMART; SM01204; FIST_C; 1.
PE   4: Predicted;
KW   Cell membrane; Membrane; Transmembrane; Transmembrane helix.
FT   CHAIN           1..383
FT                   /note="Uncharacterized protein Mb0644c"
FT                   /id="PRO_0000103715"
FT   TRANSMEM        49..69
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        347..367
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   383 AA;  39606 MW;  8C3E68C39426A699 CRC64;
     MRIGVGVSTA PDVRRAAAEA AAHAREELAG GTPALAVLLG SRSHTDQAVD LLAAVQASVE
     PAALIGCVAQ GIVAGRHELE NEPAVAVWLA SGPPAETFHL DFVRTGSGAL ITGYRFDRTA
     HDLHLLLPDP YSFPSNLLIE HLNTDLPGTT VVGGVVSGGR RRGDTRLFRD RDVLTSGLVG
     VRLPGAHSVS VVSQGCRPIG EPYIVTGADG AVITELGGRP PLHRLREIVL GMAPDEQELV
     SRGLQIGIVV DEHLAVPGQG DFLIRGLLGA DPTTGAIGIG EVVEVGATVQ FQVRDAAAAD
     KDLRLAVERA AAELPGPPVG GLLFTCNGRG RRMFGVTDHD ASTIEDLLGG IPLAGFFAAG
     EIGPVAGHNA LHGFTASMAL FVD