ID   Y647_MYCTU              Reviewed;         488 AA.
AC   P9WQI1; L0T4B8; P96936;
DT   16-APR-2014, integrated into UniProtKB/Swiss-Prot.
DT   16-APR-2014, sequence version 1.
DT   03-AUG-2022, entry version 34.
DE   RecName: Full=Uncharacterized protein Rv0647c;
GN   OrderedLocusNames=Rv0647c; ORFNames=MTCY20H10.28c;
OS   Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv).
OC   Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
OC   Mycobacterium; Mycobacterium tuberculosis complex.
OX   NCBI_TaxID=83332;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 25618 / H37Rv;
RX   PubMed=9634230; DOI=10.1038/31159;
RA   Cole S.T., Brosch R., Parkhill J., Garnier T., Churcher C.M., Harris D.E.,
RA   Gordon S.V., Eiglmeier K., Gas S., Barry C.E. III, Tekaia F., Badcock K.,
RA   Basham D., Brown D., Chillingworth T., Connor R., Davies R.M., Devlin K.,
RA   Feltwell T., Gentles S., Hamlin N., Holroyd S., Hornsby T., Jagels K.,
RA   Krogh A., McLean J., Moule S., Murphy L.D., Oliver S., Osborne J.,
RA   Quail M.A., Rajandream M.A., Rogers J., Rutter S., Seeger K., Skelton S.,
RA   Squares S., Squares R., Sulston J.E., Taylor K., Whitehead S.,
RA   Barrell B.G.;
RT   "Deciphering the biology of Mycobacterium tuberculosis from the complete
RT   genome sequence.";
RL   Nature 393:537-544(1998).
RN   [2]
RP   IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RC   STRAIN=ATCC 25618 / H37Rv;
RX   PubMed=21969609; DOI=10.1074/mcp.m111.011627;
RA   Kelkar D.S., Kumar D., Kumar P., Balakrishnan L., Muthusamy B., Yadav A.K.,
RA   Shrivastava P., Marimuthu A., Anand S., Sundaram H., Kingsbury R.,
RA   Harsha H.C., Nair B., Prasad T.S., Chauhan D.S., Katoch K., Katoch V.M.,
RA   Kumar P., Chaerkady R., Ramachandran S., Dash D., Pandey A.;
RT   "Proteogenomic analysis of Mycobacterium tuberculosis by high resolution
RT   mass spectrometry.";
RL   Mol. Cell. Proteomics 10:M111.011627-M111.011627(2011).
CC   -!- SIMILARITY: Belongs to the protein kinase superfamily. ADCK protein
CC       kinase family. {ECO:0000305}.
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DR   EMBL; AL123456; CCP43390.1; -; Genomic_DNA.
DR   PIR; D70614; D70614.
DR   RefSeq; NP_215161.1; NC_000962.3.
DR   RefSeq; WP_003403317.1; NC_000962.3.
DR   AlphaFoldDB; P9WQI1; -.
DR   SMR; P9WQI1; -.
DR   STRING; 83332.Rv0647c; -.
DR   PaxDb; P9WQI1; -.
DR   GeneID; 888070; -.
DR   KEGG; mtu:Rv0647c; -.
DR   PATRIC; fig|83332.111.peg.718; -.
DR   TubercuList; Rv0647c; -.
DR   eggNOG; COG0661; Bacteria.
DR   PhylomeDB; P9WQI1; -.
DR   Proteomes; UP000001584; Chromosome.
DR   GO; GO:0005829; C:cytosol; HDA:MTBBASE.
DR   GO; GO:0009274; C:peptidoglycan-based cell wall; HDA:MTBBASE.
DR   GO; GO:0005886; C:plasma membrane; HDA:MTBBASE.
DR   GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR   GO; GO:0004672; F:protein kinase activity; IEA:InterPro.
DR   GO; GO:0006468; P:protein phosphorylation; IEA:InterPro.
DR   InterPro; IPR004147; ABC1_dom.
DR   InterPro; IPR011009; Kinase-like_dom_sf.
DR   InterPro; IPR000719; Prot_kinase_dom.
DR   Pfam; PF03109; ABC1; 1.
DR   SUPFAM; SSF56112; SSF56112; 1.
PE   1: Evidence at protein level;
KW   Reference proteome.
FT   CHAIN           1..488
FT                   /note="Uncharacterized protein Rv0647c"
FT                   /id="PRO_0000200735"
SQ   SEQUENCE   488 AA;  54824 MW;  1F66FE8AADF92F63 CRC64;
     MRAEIGPDFR PHYTFGDAYP ASERAHVNWE LSAPVWHTAQ MGSTTHREVA KLDRVPLPVE
     AARVAATGWQ VTRTAVRFIG RLPRKGPWQQ KVIKELPQTF ADLGPTYVKF GQIIASSPGA
     FGESLSREFR GLLDRVPPAK TDEVHKLFVE ELGDEPARLF ASFEEEPFAS ASIAQVHYAT
     LRSGEEVVVK IQRPGIRRRV AADLQILKRF AQTVELAKLG RRLSAQDVVA DFADNLAEEL
     DFRLEAQSME AWVSHLHASP LGKNIRVPQV HWDFTTERVL TMERVHGIRI DNAAAIRKAG
     FDGVELVKAL LFSVFEGGLR HGLFHGDLHA GNLYVDEAGR IVFFDFGIMG RIDPRTRWLL
     RELVYALLVK KDHAAAGKIV VLMGAVGTMK PETQAAKDLE RFATPLTMQS LGDMSYADIG
     RQLSALADAY DVKLPRELVL IGKQFLYVER YMKLLAPRWQ MMSDPQLTGY FANFMVEVSR
     EHQSDIEV