ID   Y652_STRR6              Reviewed;         281 AA.
AC   Q8DQI6;
DT   30-AUG-2005, integrated into UniProtKB/Swiss-Prot.
DT   01-MAR-2003, sequence version 1.
DT   03-AUG-2022, entry version 82.
DE   RecName: Full=DegV domain-containing protein spr0652;
GN   OrderedLocusNames=spr0652;
OS   Streptococcus pneumoniae (strain ATCC BAA-255 / R6).
OC   Bacteria; Firmicutes; Bacilli; Lactobacillales; Streptococcaceae;
OC   Streptococcus.
OX   NCBI_TaxID=171101;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC BAA-255 / R6;
RX   PubMed=11544234; DOI=10.1128/jb.183.19.5709-5717.2001;
RA   Hoskins J., Alborn W.E. Jr., Arnold J., Blaszczak L.C., Burgett S.,
RA   DeHoff B.S., Estrem S.T., Fritz L., Fu D.-J., Fuller W., Geringer C.,
RA   Gilmour R., Glass J.S., Khoja H., Kraft A.R., Lagace R.E., LeBlanc D.J.,
RA   Lee L.N., Lefkowitz E.J., Lu J., Matsushima P., McAhren S.M., McHenney M.,
RA   McLeaster K., Mundy C.W., Nicas T.I., Norris F.H., O'Gara M., Peery R.B.,
RA   Robertson G.T., Rockey P., Sun P.-M., Winkler M.E., Yang Y.,
RA   Young-Bellido M., Zhao G., Zook C.A., Baltz R.H., Jaskunas S.R.,
RA   Rosteck P.R. Jr., Skatrud P.L., Glass J.I.;
RT   "Genome of the bacterium Streptococcus pneumoniae strain R6.";
RL   J. Bacteriol. 183:5709-5717(2001).
CC   -!- FUNCTION: May bind long-chain fatty acids, such as palmitate, and may
CC       play a role in lipid transport or fatty acid metabolism. {ECO:0000250}.
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DR   EMBL; AE007317; AAK99456.1; -; Genomic_DNA.
DR   PIR; D97953; D97953.
DR   RefSeq; NP_358246.1; NC_003098.1.
DR   RefSeq; WP_000219939.1; NC_003098.1.
DR   PDB; 6CNG; X-ray; 1.47 A; A/D=1-281.
DR   PDBsum; 6CNG; -.
DR   AlphaFoldDB; Q8DQI6; -.
DR   SMR; Q8DQI6; -.
DR   STRING; 171101.spr0652; -.
DR   EnsemblBacteria; AAK99456; AAK99456; spr0652.
DR   GeneID; 60232855; -.
DR   GeneID; 66805890; -.
DR   KEGG; spr:spr0652; -.
DR   PATRIC; fig|171101.6.peg.724; -.
DR   eggNOG; COG1307; Bacteria.
DR   HOGENOM; CLU_048251_2_0_9; -.
DR   OMA; HCENEAD; -.
DR   Proteomes; UP000000586; Chromosome.
DR   GO; GO:0008289; F:lipid binding; IEA:UniProtKB-KW.
DR   Gene3D; 3.30.1180.10; -; 1.
DR   InterPro; IPR003797; DegV.
DR   InterPro; IPR043168; DegV_C.
DR   Pfam; PF02645; DegV; 1.
DR   TIGRFAMs; TIGR00762; DegV; 1.
DR   PROSITE; PS51482; DEGV; 1.
PE   1: Evidence at protein level;
KW   3D-structure; Lipid-binding; Reference proteome.
FT   CHAIN           1..281
FT                   /note="DegV domain-containing protein spr0652"
FT                   /id="PRO_0000209797"
FT   DOMAIN          3..280
FT                   /note="DegV"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00815"
FT   BINDING         63
FT                   /ligand="hexadecanoate"
FT                   /ligand_id="ChEBI:CHEBI:7896"
FT                   /evidence="ECO:0000250|UniProtKB:Q9X1H9"
FT   BINDING         91
FT                   /ligand="hexadecanoate"
FT                   /ligand_id="ChEBI:CHEBI:7896"
FT                   /evidence="ECO:0000250|UniProtKB:Q9X1H9"
FT   STRAND          3..8
FT                   /evidence="ECO:0007829|PDB:6CNG"
FT   STRAND          23..28
FT                   /evidence="ECO:0007829|PDB:6CNG"
FT   STRAND          31..34
FT                   /evidence="ECO:0007829|PDB:6CNG"
FT   STRAND          37..40
FT                   /evidence="ECO:0007829|PDB:6CNG"
FT   HELIX           47..56
FT                   /evidence="ECO:0007829|PDB:6CNG"
FT   STRAND          62..64
FT                   /evidence="ECO:0007829|PDB:6CNG"
FT   HELIX           68..75
FT                   /evidence="ECO:0007829|PDB:6CNG"
FT   STRAND          79..86
FT                   /evidence="ECO:0007829|PDB:6CNG"
FT   TURN            88..90
FT                   /evidence="ECO:0007829|PDB:6CNG"
FT   HELIX           93..107
FT                   /evidence="ECO:0007829|PDB:6CNG"
FT   STRAND          112..117
FT                   /evidence="ECO:0007829|PDB:6CNG"
FT   HELIX           123..137
FT                   /evidence="ECO:0007829|PDB:6CNG"
FT   HELIX           142..154
FT                   /evidence="ECO:0007829|PDB:6CNG"
FT   STRAND          156..163
FT                   /evidence="ECO:0007829|PDB:6CNG"
FT   HELIX           166..170
FT                   /evidence="ECO:0007829|PDB:6CNG"
FT   HELIX           176..181
FT                   /evidence="ECO:0007829|PDB:6CNG"
FT   STRAND          182..193
FT                   /evidence="ECO:0007829|PDB:6CNG"
FT   STRAND          197..207
FT                   /evidence="ECO:0007829|PDB:6CNG"
FT   HELIX           208..222
FT                   /evidence="ECO:0007829|PDB:6CNG"
FT   STRAND          224..235
FT                   /evidence="ECO:0007829|PDB:6CNG"
FT   HELIX           237..250
FT                   /evidence="ECO:0007829|PDB:6CNG"
FT   STRAND          255..260
FT                   /evidence="ECO:0007829|PDB:6CNG"
FT   HELIX           263..269
FT                   /evidence="ECO:0007829|PDB:6CNG"
FT   STRAND          274..280
FT                   /evidence="ECO:0007829|PDB:6CNG"
SQ   SEQUENCE   281 AA;  30665 MW;  B016194306843E59 CRC64;
     MTWKIIADSG CDYRQLPTPA INTTFVSVPL TIQVADQVFV DDASLDIDQM METMYATAEA
     SKSACPSPDD YLRAFEGAKN IFLVTITGTL SGSHNSAQLA KNIYLEDHPD TKIHVIDSLS
     AGGEVDLLVE KLNDLIDQGL SFEEVVEAIT AYQEKTKLLF VLAKVDNLVK NGRLSKLIGT
     VVGLLNIRMV GKASETGTLE LLQKARGSKK SVQAAYDELV KAGYAGGRIV MAQRNNEKCC
     QQLSERIRET FPQADIKILP TSGLCSFYAE EGGLLMGYEI D