ID   Y655_ARCFU              Reviewed;         425 AA.
AC   O29602;
DT   15-JUL-1998, integrated into UniProtKB/Swiss-Prot.
DT   01-JAN-1998, sequence version 1.
DT   03-AUG-2022, entry version 96.
DE   RecName: Full=Metalloprotease AF_0655;
DE            EC=3.4.-.-;
GN   OrderedLocusNames=AF_0655;
OS   Archaeoglobus fulgidus (strain ATCC 49558 / DSM 4304 / JCM 9628 / NBRC
OS   100126 / VC-16).
OC   Archaea; Euryarchaeota; Archaeoglobi; Archaeoglobales; Archaeoglobaceae;
OC   Archaeoglobus.
OX   NCBI_TaxID=224325;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 49558 / DSM 4304 / JCM 9628 / NBRC 100126 / VC-16;
RX   PubMed=9389475; DOI=10.1038/37052;
RA   Klenk H.-P., Clayton R.A., Tomb J.-F., White O., Nelson K.E., Ketchum K.A.,
RA   Dodson R.J., Gwinn M.L., Hickey E.K., Peterson J.D., Richardson D.L.,
RA   Kerlavage A.R., Graham D.E., Kyrpides N.C., Fleischmann R.D.,
RA   Quackenbush J., Lee N.H., Sutton G.G., Gill S.R., Kirkness E.F.,
RA   Dougherty B.A., McKenney K., Adams M.D., Loftus B.J., Peterson S.N.,
RA   Reich C.I., McNeil L.K., Badger J.H., Glodek A., Zhou L., Overbeek R.,
RA   Gocayne J.D., Weidman J.F., McDonald L.A., Utterback T.R., Cotton M.D.,
RA   Spriggs T., Artiach P., Kaine B.P., Sykes S.M., Sadow P.W., D'Andrea K.P.,
RA   Bowman C., Fujii C., Garland S.A., Mason T.M., Olsen G.J., Fraser C.M.,
RA   Smith H.O., Woese C.R., Venter J.C.;
RT   "The complete genome sequence of the hyperthermophilic, sulphate-reducing
RT   archaeon Archaeoglobus fulgidus.";
RL   Nature 390:364-370(1997).
CC   -!- FUNCTION: Probable metalloprotease. {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the peptidase U62 family. {ECO:0000305}.
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DR   EMBL; AE000782; AAB90585.1; -; Genomic_DNA.
DR   PIR; G69331; G69331.
DR   RefSeq; WP_010878158.1; NC_000917.1.
DR   AlphaFoldDB; O29602; -.
DR   SMR; O29602; -.
DR   STRING; 224325.AF_0655; -.
DR   DNASU; 1483873; -.
DR   EnsemblBacteria; AAB90585; AAB90585; AF_0655.
DR   GeneID; 24794255; -.
DR   KEGG; afu:AF_0655; -.
DR   eggNOG; arCOG00321; Archaea.
DR   HOGENOM; CLU_026425_1_2_2; -.
DR   OMA; ENGETEH; -.
DR   OrthoDB; 22382at2157; -.
DR   PhylomeDB; O29602; -.
DR   Proteomes; UP000002199; Chromosome.
DR   GO; GO:0008237; F:metallopeptidase activity; IEA:UniProtKB-KW.
DR   GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR   Gene3D; 3.30.2290.10; -; 1.
DR   InterPro; IPR045569; Metalloprtase-TldD/E_C.
DR   InterPro; IPR045570; Metalloprtase-TldD/E_cen_dom.
DR   InterPro; IPR002510; Metalloprtase-TldD/E_N.
DR   InterPro; IPR025502; TldD.
DR   InterPro; IPR035068; TldD/PmbA_N.
DR   InterPro; IPR036059; TldD/PmbA_sf.
DR   Pfam; PF01523; PmbA_TldD; 1.
DR   Pfam; PF19289; PmbA_TldD_C; 1.
DR   Pfam; PF19290; PmbA_TldD_M; 1.
DR   PIRSF; PIRSF004919; TldD; 1.
DR   SUPFAM; SSF111283; SSF111283; 1.
PE   3: Inferred from homology;
KW   Hydrolase; Metalloprotease; Protease; Reference proteome.
FT   CHAIN           1..425
FT                   /note="Metalloprotease AF_0655"
FT                   /id="PRO_0000142363"
SQ   SEQUENCE   425 AA;  47188 MW;  7FD0AAAE169715A6 CRC64;
     MRFWDIRRVE NVSLNLQLEN GKLEKPRYNK STSKGFRVLK NGFWGIFEGN VADDEGLRQA
     EKNAFTQGDG DIEEIATKGR YRMRVKRDPQ DMSIEEKVEL LKDLEKIIRD VCVSTKLVYF
     ENRRVLQYRD SCGSEVEYEV LRTGVSIMGV GKGRSLQFLS KRQMRVGGYE VLDGVDEKAY
     EIVEVLPKLV NALAPPSGEM SVVMDSSLAG VFVHEAFGHA VEADHVLQGA TVLKGRLNEK
     VADESVTIID DPTLPEFGFF PFDDEGVRAE KKVIVEDGVL KSFLHSRETA KKLGGVAGNA
     RSQGVDVPIV RMSNTYIDTH HYSFDELLEE CRDGVYLVGS RGGETNPATG YFHFNAQYGY
     LIKNGELAEM VRDVSLSGNT LEILRNVKIG REIEFDPGFC GKAGQLVPVS DGSPPVLCRA
     TVGGA