Y663_HAEIN
ID Y663_HAEIN Reviewed; 560 AA.
AC P71355;
DT 30-MAY-2000, integrated into UniProtKB/Swiss-Prot.
DT 01-FEB-1997, sequence version 1.
DT 03-AUG-2022, entry version 128.
DE RecName: Full=Uncharacterized ABC transporter ATP-binding protein HI_0663;
GN OrderedLocusNames=HI_0663;
OS Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd).
OC Bacteria; Proteobacteria; Gammaproteobacteria; Pasteurellales;
OC Pasteurellaceae; Haemophilus.
OX NCBI_TaxID=71421;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 51907 / DSM 11121 / KW20 / Rd;
RX PubMed=7542800; DOI=10.1126/science.7542800;
RA Fleischmann R.D., Adams M.D., White O., Clayton R.A., Kirkness E.F.,
RA Kerlavage A.R., Bult C.J., Tomb J.-F., Dougherty B.A., Merrick J.M.,
RA McKenney K., Sutton G.G., FitzHugh W., Fields C.A., Gocayne J.D.,
RA Scott J.D., Shirley R., Liu L.-I., Glodek A., Kelley J.M., Weidman J.F.,
RA Phillips C.A., Spriggs T., Hedblom E., Cotton M.D., Utterback T.R.,
RA Hanna M.C., Nguyen D.T., Saudek D.M., Brandon R.C., Fine L.D.,
RA Fritchman J.L., Fuhrmann J.L., Geoghagen N.S.M., Gnehm C.L., McDonald L.A.,
RA Small K.V., Fraser C.M., Smith H.O., Venter J.C.;
RT "Whole-genome random sequencing and assembly of Haemophilus influenzae
RT Rd.";
RL Science 269:496-512(1995).
CC -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000305}; Multi-pass
CC membrane protein {ECO:0000255|PROSITE-ProRule:PRU00441}.
CC -!- SIMILARITY: Belongs to the ABC transporter superfamily. {ECO:0000305}.
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DR EMBL; L42023; AAC22320.1; -; Genomic_DNA.
DR RefSeq; NP_438822.1; NC_000907.1.
DR AlphaFoldDB; P71355; -.
DR SMR; P71355; -.
DR STRING; 71421.HI_0663; -.
DR EnsemblBacteria; AAC22320; AAC22320; HI_0663.
DR KEGG; hin:HI_0663; -.
DR PATRIC; fig|71421.8.peg.692; -.
DR eggNOG; COG4988; Bacteria.
DR HOGENOM; CLU_000604_84_9_6; -.
DR OMA; TMQLNSV; -.
DR PhylomeDB; P71355; -.
DR Proteomes; UP000000579; Chromosome.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0140359; F:ABC-type transporter activity; IEA:InterPro.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0042626; F:ATPase-coupled transmembrane transporter activity; IBA:GO_Central.
DR GO; GO:0055085; P:transmembrane transport; IBA:GO_Central.
DR Gene3D; 1.20.1560.10; -; 1.
DR Gene3D; 3.40.50.300; -; 1.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR011527; ABC1_TM_dom.
DR InterPro; IPR036640; ABC1_TM_sf.
DR InterPro; IPR003439; ABC_transporter-like_ATP-bd.
DR InterPro; IPR017871; ABC_transporter-like_CS.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR039421; Type_1_exporter.
DR PANTHER; PTHR24221; PTHR24221; 1.
DR Pfam; PF00664; ABC_membrane; 1.
DR Pfam; PF00005; ABC_tran; 1.
DR SMART; SM00382; AAA; 1.
DR SUPFAM; SSF52540; SSF52540; 1.
DR SUPFAM; SSF90123; SSF90123; 1.
DR PROSITE; PS50929; ABC_TM1F; 1.
DR PROSITE; PS00211; ABC_TRANSPORTER_1; 1.
DR PROSITE; PS50893; ABC_TRANSPORTER_2; 1.
PE 3: Inferred from homology;
KW ATP-binding; Cell inner membrane; Cell membrane; Membrane;
KW Nucleotide-binding; Reference proteome; Transmembrane; Transmembrane helix;
KW Transport.
FT CHAIN 1..560
FT /note="Uncharacterized ABC transporter ATP-binding protein
FT HI_0663"
FT /id="PRO_0000093201"
FT TRANSMEM 2..22
FT /note="Helical"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"
FT TRANSMEM 32..52
FT /note="Helical"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"
FT TRANSMEM 108..128
FT /note="Helical"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"
FT TRANSMEM 138..160
FT /note="Helical"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"
FT TRANSMEM 168..188
FT /note="Helical"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"
FT TRANSMEM 223..243
FT /note="Helical"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"
FT TRANSMEM 249..269
FT /note="Helical"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"
FT DOMAIN 1..281
FT /note="ABC transmembrane type-1"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"
FT DOMAIN 314..547
FT /note="ABC transporter"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00434"
FT BINDING 347..354
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00434"
SQ SEQUENCE 560 AA; 62197 MW; 65ADC0D0BC1347DE CRC64;
MLWNWVALVG GIISAVVFSY ILQAAYFHEL SLLSAVILGI VLIAALALRA FAGKKSVQAS
YFASTKVKHE LRSLIYRKLA SMPLNQVNQQ STSSIIQVAS EGVEQLEIYF GRYLPQLFYS
LLAPLTLFAF LIFFSFKTAI ILLICVPLIP MSIIAVNKIA KKLLAKYWSI YVGLGSSFLD
NLQGLITLKI YQDDAYKAKA MDKEAEHFRK ITMKVLTMQL NSVSLMDLLA YGGAAIGILT
ALLQFQNAQL SVLGVILFIL LSSEFFIPLR LLGSFFHVAM NGKAASDKIF TLLDTPVETQ
QSAVDFEAKN NVQVEIKDLH FSYSEEKPAI TGLNLSILPN QLSVFVGKSG CGKSTLVSLL
MGFNKAQQGE ILFNGQNALN IDRTSFYQKV SLVSHSSYVF KGTLRENMTM AKIDATDEQI
YACLEQVNLA QFVRDNGGLD MQLLSRGANL SGGQIQRLAL ARALLHNAEL YIFDEATSNI
DVESEEIILQ FIQQFKQQKT IVMISHRLAN AVNADCINVL DQGKLIEQGT HKELMEKQGA
YAEMFQQQKD LEQIREVANA
