ID   Y663_MYCPA              Reviewed;         268 AA.
AC   Q743C2;
DT   20-JAN-2009, integrated into UniProtKB/Swiss-Prot.
DT   05-JUL-2004, sequence version 1.
DT   03-AUG-2022, entry version 77.
DE   RecName: Full=Putative S-adenosyl-L-methionine-dependent methyltransferase MAP_0663;
DE            EC=2.1.1.-;
GN   OrderedLocusNames=MAP_0663;
OS   Mycolicibacterium paratuberculosis (strain ATCC BAA-968 / K-10)
OS   (Mycobacterium paratuberculosis).
OC   Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
OC   Mycobacterium; Mycobacterium avium complex (MAC).
OX   NCBI_TaxID=262316;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC BAA-968 / K-10;
RX   PubMed=16116077; DOI=10.1073/pnas.0505662102;
RA   Li L., Bannantine J.P., Zhang Q., Amonsin A., May B.J., Alt D., Banerji N.,
RA   Kanjilal S., Kapur V.;
RT   "The complete genome sequence of Mycobacterium avium subspecies
RT   paratuberculosis.";
RL   Proc. Natl. Acad. Sci. U.S.A. 102:12344-12349(2005).
CC   -!- FUNCTION: Exhibits S-adenosyl-L-methionine-dependent methyltransferase
CC       activity. {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the UPF0677 family. {ECO:0000305}.
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DR   EMBL; AE016958; AAS02980.1; -; Genomic_DNA.
DR   AlphaFoldDB; Q743C2; -.
DR   SMR; Q743C2; -.
DR   STRING; 262316.MAP_0663; -.
DR   EnsemblBacteria; AAS02980; AAS02980; MAP_0663.
DR   KEGG; mpa:MAP_0663; -.
DR   PATRIC; fig|262316.17.peg.698; -.
DR   eggNOG; COG3315; Bacteria.
DR   HOGENOM; CLU_056160_2_1_11; -.
DR   OMA; TRFYDQF; -.
DR   Proteomes; UP000000580; Chromosome.
DR   GO; GO:0008168; F:methyltransferase activity; IEA:UniProtKB-KW.
DR   GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR   Gene3D; 3.40.50.150; -; 1.
DR   InterPro; IPR011610; CHP00027_methylltransferase.
DR   InterPro; IPR007213; Ppm1/Ppm2/Tcmp.
DR   InterPro; IPR029063; SAM-dependent_MTases_sf.
DR   Pfam; PF04072; LCM; 1.
DR   SUPFAM; SSF53335; SSF53335; 1.
DR   TIGRFAMs; TIGR00027; mthyl_TIGR00027; 1.
PE   3: Inferred from homology;
KW   Methyltransferase; Reference proteome; S-adenosyl-L-methionine;
KW   Transferase.
FT   CHAIN           1..268
FT                   /note="Putative S-adenosyl-L-methionine-dependent
FT                   methyltransferase MAP_0663"
FT                   /id="PRO_0000361191"
FT   BINDING         124
FT                   /ligand="S-adenosyl-L-methionine"
FT                   /ligand_id="ChEBI:CHEBI:59789"
FT                   /evidence="ECO:0000250"
FT   BINDING         153..154
FT                   /ligand="S-adenosyl-L-methionine"
FT                   /ligand_id="ChEBI:CHEBI:59789"
FT                   /evidence="ECO:0000250"
SQ   SEQUENCE   268 AA;  29499 MW;  3281E855E5E0CD9E CRC64;
     MARTDRDRWD LATSVGATAT MVAAQRALSS DANLIDDPYA APLVRAVGID VYVRLVDGEI
     QPGTSEFDPH RMAKGMACRT RFYDDFFLDA ARAGVGQAVI LASGLDARAY RLPWPAGTVV
     YEVDMPDVIE FKTLTLADLG AQPTAQRRTV AIDLRDDWAA ALREERFDTQ APAAWSAEGL
     LVYLPEQAQD ALFDNITALS APGSRLAFDF VPDTAVFADP RWRAHHDRMS ELGFEVDFND
     LVYHGERSHI VDHLSGRGCS LVPLFRVG