Y664_HAEIN
ID Y664_HAEIN Reviewed; 552 AA.
AC Q57538;
DT 01-NOV-1997, integrated into UniProtKB/Swiss-Prot.
DT 01-NOV-1996, sequence version 1.
DT 03-AUG-2022, entry version 133.
DE RecName: Full=Probable ABC transporter ATP-binding/permease protein HI_0664;
GN OrderedLocusNames=HI_0664;
OS Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd).
OC Bacteria; Proteobacteria; Gammaproteobacteria; Pasteurellales;
OC Pasteurellaceae; Haemophilus.
OX NCBI_TaxID=71421;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 51907 / DSM 11121 / KW20 / Rd;
RX PubMed=7542800; DOI=10.1126/science.7542800;
RA Fleischmann R.D., Adams M.D., White O., Clayton R.A., Kirkness E.F.,
RA Kerlavage A.R., Bult C.J., Tomb J.-F., Dougherty B.A., Merrick J.M.,
RA McKenney K., Sutton G.G., FitzHugh W., Fields C.A., Gocayne J.D.,
RA Scott J.D., Shirley R., Liu L.-I., Glodek A., Kelley J.M., Weidman J.F.,
RA Phillips C.A., Spriggs T., Hedblom E., Cotton M.D., Utterback T.R.,
RA Hanna M.C., Nguyen D.T., Saudek D.M., Brandon R.C., Fine L.D.,
RA Fritchman J.L., Fuhrmann J.L., Geoghagen N.S.M., Gnehm C.L., McDonald L.A.,
RA Small K.V., Fraser C.M., Smith H.O., Venter J.C.;
RT "Whole-genome random sequencing and assembly of Haemophilus influenzae
RT Rd.";
RL Science 269:496-512(1995).
RN [2]
RP IDENTIFICATION BY MASS SPECTROMETRY.
RC STRAIN=ATCC 51907 / DSM 11121 / KW20 / Rd;
RX PubMed=10675023;
RX DOI=10.1002/(sici)1522-2683(20000101)21:2<411::aid-elps411>3.0.co;2-4;
RA Langen H., Takacs B., Evers S., Berndt P., Lahm H.W., Wipf B., Gray C.,
RA Fountoulakis M.;
RT "Two-dimensional map of the proteome of Haemophilus influenzae.";
RL Electrophoresis 21:411-429(2000).
CC -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000305}; Multi-pass
CC membrane protein {ECO:0000255|PROSITE-ProRule:PRU00441}.
CC -!- SIMILARITY: Belongs to the ABC transporter superfamily. Lipid exporter
CC (TC 3.A.1.106) family. {ECO:0000305}.
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DR EMBL; L42023; AAC22321.1; -; Genomic_DNA.
DR PIR; A64085; A64085.
DR RefSeq; NP_438823.1; NC_000907.1.
DR RefSeq; WP_005667625.1; NC_000907.1.
DR AlphaFoldDB; Q57538; -.
DR SMR; Q57538; -.
DR STRING; 71421.HI_0664; -.
DR EnsemblBacteria; AAC22321; AAC22321; HI_0664.
DR KEGG; hin:HI_0664; -.
DR PATRIC; fig|71421.8.peg.693; -.
DR eggNOG; COG1132; Bacteria.
DR HOGENOM; CLU_000604_84_9_6; -.
DR OMA; HIMAFTI; -.
DR PhylomeDB; Q57538; -.
DR BioCyc; HINF71421:G1GJ1-698-MON; -.
DR Proteomes; UP000000579; Chromosome.
DR GO; GO:0005887; C:integral component of plasma membrane; IBA:GO_Central.
DR GO; GO:0140359; F:ABC-type transporter activity; IEA:InterPro.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0042626; F:ATPase-coupled transmembrane transporter activity; IBA:GO_Central.
DR GO; GO:0045454; P:cell redox homeostasis; IEA:InterPro.
DR GO; GO:0034775; P:glutathione transmembrane transport; IEA:InterPro.
DR Gene3D; 1.20.1560.10; -; 1.
DR Gene3D; 3.40.50.300; -; 1.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR011527; ABC1_TM_dom.
DR InterPro; IPR036640; ABC1_TM_sf.
DR InterPro; IPR014223; ABC_CydC.
DR InterPro; IPR003439; ABC_transporter-like_ATP-bd.
DR InterPro; IPR027417; P-loop_NTPase.
DR Pfam; PF00664; ABC_membrane; 1.
DR Pfam; PF00005; ABC_tran; 1.
DR SMART; SM00382; AAA; 1.
DR SUPFAM; SSF52540; SSF52540; 1.
DR SUPFAM; SSF90123; SSF90123; 1.
DR TIGRFAMs; TIGR02868; CydC; 1.
DR PROSITE; PS50929; ABC_TM1F; 1.
DR PROSITE; PS50893; ABC_TRANSPORTER_2; 1.
PE 1: Evidence at protein level;
KW ATP-binding; Cell inner membrane; Cell membrane; Membrane;
KW Nucleotide-binding; Reference proteome; Transmembrane; Transmembrane helix;
KW Transport.
FT CHAIN 1..552
FT /note="Probable ABC transporter ATP-binding/permease
FT protein HI_0664"
FT /id="PRO_0000093202"
FT TRANSMEM 22..42
FT /note="Helical"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"
FT TRANSMEM 52..72
FT /note="Helical"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"
FT TRANSMEM 139..159
FT /note="Helical"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"
FT TRANSMEM 162..182
FT /note="Helical"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"
FT TRANSMEM 253..273
FT /note="Helical"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"
FT TRANSMEM 278..298
FT /note="Helical"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"
FT DOMAIN 23..307
FT /note="ABC transmembrane type-1"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"
FT DOMAIN 340..552
FT /note="ABC transporter"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00434"
FT BINDING 372..379
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00434"
SQ SEQUENCE 552 AA; 61294 MW; B14E31CDB07AD857 CRC64;
MRKNGFVVMG HLLKLVTPLA HIMAFTITMG TLGFLAAIFI MVLGATGLVN LLNFDTHLSF
SGILTALIVL AVARGALRYL EQMSGHYIAF KLLALLRDKV FSSLRRLAFV KLQDKQAGQL
VSLVTNDIEL LEVFYAHTIA PIMIAFFTSA ILLLVFAQLS SWFVLVALAA YLTVGVILPI
ITTKLAREDG RRYRELVGEM NDFFLDSVRG MKEIQLFGYA KQRLDEIQQR SQKIDTAFER
IKDQEAKVRV YTEVAVSVFN IIMLFTGLIL FSLDKIDFAA FLIGVILLMS SYGPVIALSN
LSSNLLQTLA SGERVLSLLA EEPELKDVES AVDLKDVSRI DVENVNFAYG EEQILSDVSL
SVKKGEILGI HGRSGSGKST LLKLLMRFYD PKSGSIKING ETLPNINTCS LRDNMAYITQ
QTYIFNETIE ENIRLARRDA TLEEIMEAAK KASIHDFILS LPQGYQTKMT ELGGNLSDGE
KQRIGIARAF LHNAPIILLD EPTSNLDSLN EAMILKSLLN VKAEKLIILV SHRQSTMAIC
DQVIGIENGR MS
