ID   Y666_METJA              Reviewed;         398 AA.
AC   Q58080;
DT   01-NOV-1997, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1996, sequence version 1.
DT   25-MAY-2022, entry version 113.
DE   RecName: Full=Putative molybdopterin biosynthesis protein MJ0666;
GN   OrderedLocusNames=MJ0666;
OS   Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM
OS   10045 / NBRC 100440) (Methanococcus jannaschii).
OC   Archaea; Euryarchaeota; Methanomada group; Methanococci; Methanococcales;
OC   Methanocaldococcaceae; Methanocaldococcus.
OX   NCBI_TaxID=243232;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440;
RX   PubMed=8688087; DOI=10.1126/science.273.5278.1058;
RA   Bult C.J., White O., Olsen G.J., Zhou L., Fleischmann R.D., Sutton G.G.,
RA   Blake J.A., FitzGerald L.M., Clayton R.A., Gocayne J.D., Kerlavage A.R.,
RA   Dougherty B.A., Tomb J.-F., Adams M.D., Reich C.I., Overbeek R.,
RA   Kirkness E.F., Weinstock K.G., Merrick J.M., Glodek A., Scott J.L.,
RA   Geoghagen N.S.M., Weidman J.F., Fuhrmann J.L., Nguyen D., Utterback T.R.,
RA   Kelley J.M., Peterson J.D., Sadow P.W., Hanna M.C., Cotton M.D.,
RA   Roberts K.M., Hurst M.A., Kaine B.P., Borodovsky M., Klenk H.-P.,
RA   Fraser C.M., Smith H.O., Woese C.R., Venter J.C.;
RT   "Complete genome sequence of the methanogenic archaeon, Methanococcus
RT   jannaschii.";
RL   Science 273:1058-1073(1996).
CC   -!- PATHWAY: Cofactor biosynthesis; molybdopterin biosynthesis.
CC   -!- SIMILARITY: Belongs to the MoeA family. {ECO:0000305}.
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DR   EMBL; L77117; AAB98661.1; -; Genomic_DNA.
DR   PIR; B64383; B64383.
DR   RefSeq; WP_010870171.1; NC_000909.1.
DR   AlphaFoldDB; Q58080; -.
DR   SMR; Q58080; -.
DR   STRING; 243232.MJ_0666; -.
DR   EnsemblBacteria; AAB98661; AAB98661; MJ_0666.
DR   GeneID; 1451532; -.
DR   KEGG; mja:MJ_0666; -.
DR   eggNOG; arCOG00216; Archaea.
DR   HOGENOM; CLU_010186_7_2_2; -.
DR   InParanoid; Q58080; -.
DR   OMA; MTGAMVP; -.
DR   OrthoDB; 51611at2157; -.
DR   PhylomeDB; Q58080; -.
DR   UniPathway; UPA00344; -.
DR   Proteomes; UP000000805; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
DR   GO; GO:0061599; F:molybdopterin molybdotransferase activity; IBA:GO_Central.
DR   GO; GO:0006777; P:Mo-molybdopterin cofactor biosynthetic process; IBA:GO_Central.
DR   GO; GO:0018315; P:molybdenum incorporation into molybdenum-molybdopterin complex; IBA:GO_Central.
DR   GO; GO:0032324; P:molybdopterin cofactor biosynthetic process; IEA:InterPro.
DR   CDD; cd00887; MoeA; 1.
DR   Gene3D; 2.40.340.10; -; 1.
DR   Gene3D; 3.40.980.10; -; 1.
DR   InterPro; IPR036425; MoaB/Mog-like_dom_sf.
DR   InterPro; IPR001453; MoaB/Mog_dom.
DR   InterPro; IPR008284; MoCF_biosynth_CS.
DR   InterPro; IPR038987; MoeA-like.
DR   InterPro; IPR005111; MoeA_C_domain_IV.
DR   InterPro; IPR036688; MoeA_C_domain_IV_sf.
DR   InterPro; IPR005110; MoeA_linker/N.
DR   InterPro; IPR036135; MoeA_linker/N_sf.
DR   PANTHER; PTHR10192; PTHR10192; 1.
DR   Pfam; PF00994; MoCF_biosynth; 1.
DR   Pfam; PF03454; MoeA_C; 1.
DR   Pfam; PF03453; MoeA_N; 1.
DR   SMART; SM00852; MoCF_biosynth; 1.
DR   SUPFAM; SSF53218; SSF53218; 1.
DR   SUPFAM; SSF63867; SSF63867; 1.
DR   SUPFAM; SSF63882; SSF63882; 1.
DR   TIGRFAMs; TIGR00177; molyb_syn; 1.
DR   PROSITE; PS01079; MOCF_BIOSYNTHESIS_2; 1.
PE   3: Inferred from homology;
KW   Molybdenum cofactor biosynthesis; Reference proteome.
FT   CHAIN           1..398
FT                   /note="Putative molybdopterin biosynthesis protein MJ0666"
FT                   /id="PRO_0000171004"
SQ   SEQUENCE   398 AA;  44418 MW;  81747A9908607ACB CRC64;
     MKLIKNLMPL KSAEKIVFEK LSEYLDENKK VKEVDIVEAL NRISAEDIKA PIDLPYFNKA
     AMDGYAVIAE DTFGASETNP IILNLADGDE ITYGEAKKIF TGDKLPKNAN AVVMKEFCNE
     VDDFVEVYKT VHPNENVSRI GEDVKKGDVV LKKGEIINPY HLNMLASLGI KKIKVYDLSF
     GIISTGDELI NLDEIRDIEE DISKLDGKII NSNSYMLYGL VKNLGFNAKI YDIVKDDKEK
     LKKAIKTALS ENDALLITGG TSVSERDITV ETVRELGDVI VHGVNIRPGK PFGFGIINDK
     PVFMLSGYPV ASAVQFELFI QRFFIERKKV TLPLKRNMAS ELGRVDFVRV KVDIEVEPIR
     ITGSGVISSL IKSDGYILIP ENVEGYEKGE LVDVYLLK