ID   Y667_ENCCU              Reviewed;         271 AA.
AC   Q8SVC0;
DT   01-SEP-2009, integrated into UniProtKB/Swiss-Prot.
DT   01-JUN-2002, sequence version 1.
DT   25-MAY-2022, entry version 80.
DE   RecName: Full=PH domain-containing protein ECU06_0670;
GN   OrderedLocusNames=ECU06_0670;
OS   Encephalitozoon cuniculi (strain GB-M1) (Microsporidian parasite).
OC   Eukaryota; Fungi; Fungi incertae sedis; Microsporidia; Unikaryonidae;
OC   Encephalitozoon.
OX   NCBI_TaxID=284813;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=GB-M1;
RX   PubMed=11719806; DOI=10.1038/35106579;
RA   Katinka M.D., Duprat S., Cornillot E., Metenier G., Thomarat F.,
RA   Prensier G., Barbe V., Peyretaillade E., Brottier P., Wincker P.,
RA   Delbac F., El Alaoui H., Peyret P., Saurin W., Gouy M., Weissenbach J.,
RA   Vivares C.P.;
RT   "Genome sequence and gene compaction of the eukaryote parasite
RT   Encephalitozoon cuniculi.";
RL   Nature 414:450-453(2001).
RN   [2]
RP   IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS], DEVELOPMENTAL
RP   STAGE, AND SUBCELLULAR LOCATION.
RX   PubMed=16691553; DOI=10.1002/pmic.200500796;
RA   Brosson D., Kuhn L., Delbac F., Garin J., Vivares C.P., Texier C.;
RT   "Proteomic analysis of the eukaryotic parasite Encephalitozoon cuniculi
RT   (microsporidia): a reference map for proteins expressed in late sporogonial
RT   stages.";
RL   Proteomics 6:3625-3635(2006).
CC   -!- DEVELOPMENTAL STAGE: Expressed in late sporogonial stages.
CC       {ECO:0000269|PubMed:16691553}.
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DR   EMBL; AL590446; CAD25427.1; -; Genomic_DNA.
DR   RefSeq; NP_585823.1; NM_001041445.1.
DR   AlphaFoldDB; Q8SVC0; -.
DR   GeneID; 859247; -.
DR   KEGG; ecu:ECU06_0670; -.
DR   VEuPathDB; MicrosporidiaDB:ECU06_0670; -.
DR   HOGENOM; CLU_1034492_0_0_1; -.
DR   InParanoid; Q8SVC0; -.
DR   OMA; DEPAMES; -.
DR   OrthoDB; 1484568at2759; -.
DR   Proteomes; UP000000819; Chromosome VI.
DR   Gene3D; 2.30.29.30; -; 1.
DR   InterPro; IPR011993; PH-like_dom_sf.
DR   InterPro; IPR001849; PH_domain.
DR   Pfam; PF00169; PH; 1.
DR   SMART; SM00233; PH; 1.
DR   PROSITE; PS50003; PH_DOMAIN; 1.
PE   1: Evidence at protein level;
KW   Reference proteome.
FT   CHAIN           1..271
FT                   /note="PH domain-containing protein ECU06_0670"
FT                   /id="PRO_0000383033"
FT   DOMAIN          166..267
FT                   /note="PH"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00145"
FT   REGION          26..145
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        41..67
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        88..136
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   271 AA;  31322 MW;  EAD38AA6C7A8D8FA CRC64;
     MEGKDTKKKK KNIIIINDKG EMRSVAKKTL DSSESSLAQS KEVGEVDEVK GMETDAEKKD
     EPAMESKGCC KKCSNGDARG CHSERSGNYS EQPEKQEAAD GEDSSKKESP REEQTPLLDK
     EEADEKTEEN AKPSSEKKND AFIPPILGTS MTVANKEIFE DRENGNTVVE GWMWKKRRIF
     SCFWHRKYFV LTREGILKYY KADGRRHPKG NWNMKDSTEI RHYNLPSEEN SHPFRVLVFF
     PDFSFLLAFD DKNSKDYWVE KLNETIRRLK K