ID   Y674_METJA              Reviewed;         338 AA.
AC   Q58087;
DT   01-NOV-1997, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1996, sequence version 1.
DT   03-AUG-2022, entry version 97.
DE   RecName: Full=Uncharacterized protein MJ0674;
GN   OrderedLocusNames=MJ0674;
OS   Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM
OS   10045 / NBRC 100440) (Methanococcus jannaschii).
OC   Archaea; Euryarchaeota; Methanomada group; Methanococci; Methanococcales;
OC   Methanocaldococcaceae; Methanocaldococcus.
OX   NCBI_TaxID=243232;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440;
RX   PubMed=8688087; DOI=10.1126/science.273.5278.1058;
RA   Bult C.J., White O., Olsen G.J., Zhou L., Fleischmann R.D., Sutton G.G.,
RA   Blake J.A., FitzGerald L.M., Clayton R.A., Gocayne J.D., Kerlavage A.R.,
RA   Dougherty B.A., Tomb J.-F., Adams M.D., Reich C.I., Overbeek R.,
RA   Kirkness E.F., Weinstock K.G., Merrick J.M., Glodek A., Scott J.L.,
RA   Geoghagen N.S.M., Weidman J.F., Fuhrmann J.L., Nguyen D., Utterback T.R.,
RA   Kelley J.M., Peterson J.D., Sadow P.W., Hanna M.C., Cotton M.D.,
RA   Roberts K.M., Hurst M.A., Kaine B.P., Borodovsky M., Klenk H.-P.,
RA   Fraser C.M., Smith H.O., Woese C.R., Venter J.C.;
RT   "Complete genome sequence of the methanogenic archaeon, Methanococcus
RT   jannaschii.";
RL   Science 273:1058-1073(1996).
CC   -!- COFACTOR:
CC       Name=[4Fe-4S] cluster; Xref=ChEBI:CHEBI:49883; Evidence={ECO:0000305};
CC       Note=Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3
CC       cysteines and an exchangeable S-adenosyl-L-methionine. {ECO:0000305};
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; L77117; AAB98668.1; -; Genomic_DNA.
DR   PIR; B64384; B64384.
DR   RefSeq; WP_010870179.1; NC_000909.1.
DR   AlphaFoldDB; Q58087; -.
DR   SMR; Q58087; -.
DR   STRING; 243232.MJ_0674; -.
DR   PRIDE; Q58087; -.
DR   EnsemblBacteria; AAB98668; AAB98668; MJ_0674.
DR   GeneID; 1451540; -.
DR   KEGG; mja:MJ_0674; -.
DR   eggNOG; arCOG00934; Archaea.
DR   HOGENOM; CLU_062674_0_1_2; -.
DR   InParanoid; Q58087; -.
DR   OMA; GGEPTPN; -.
DR   OrthoDB; 34153at2157; -.
DR   PhylomeDB; Q58087; -.
DR   Proteomes; UP000000805; Chromosome.
DR   GO; GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.
DR   GO; GO:0003824; F:catalytic activity; IEA:InterPro.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   Gene3D; 3.20.20.70; -; 1.
DR   InterPro; IPR013785; Aldolase_TIM.
DR   InterPro; IPR040085; MJ0674-like.
DR   InterPro; IPR016431; Pyrv-formate_lyase-activ_prd.
DR   InterPro; IPR007197; rSAM.
DR   PANTHER; PTHR43075; PTHR43075; 1.
DR   Pfam; PF04055; Radical_SAM; 1.
DR   PIRSF; PIRSF004869; PflX_prd; 1.
DR   SFLD; SFLDS00029; Radical_SAM; 1.
DR   SFLD; SFLDG01099; Uncharacterised_Radical_SAM_Su; 1.
DR   PROSITE; PS51918; RADICAL_SAM; 1.
PE   4: Predicted;
KW   4Fe-4S; Iron; Iron-sulfur; Metal-binding; Reference proteome;
KW   S-adenosyl-L-methionine.
FT   CHAIN           1..338
FT                   /note="Uncharacterized protein MJ0674"
FT                   /id="PRO_0000106984"
FT   DOMAIN          111..334
FT                   /note="Radical SAM core"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01266"
FT   BINDING         129
FT                   /ligand="[4Fe-4S] cluster"
FT                   /ligand_id="ChEBI:CHEBI:49883"
FT                   /ligand_note="4Fe-4S-S-AdoMet"
FT                   /evidence="ECO:0000255"
FT   BINDING         133
FT                   /ligand="[4Fe-4S] cluster"
FT                   /ligand_id="ChEBI:CHEBI:49883"
FT                   /ligand_note="4Fe-4S-S-AdoMet"
FT                   /evidence="ECO:0000255"
FT   BINDING         136
FT                   /ligand="[4Fe-4S] cluster"
FT                   /ligand_id="ChEBI:CHEBI:49883"
FT                   /ligand_note="4Fe-4S-S-AdoMet"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   338 AA;  40020 MW;  96923543AEB9C705 CRC64;
     MKLGRYLAVS KDLAPAKFII AKCIEVEEFK GLELNELWEI HNKVLKKVDF DNFDFNDLEY
     VKPNLLDLKV EIAKNIFKNC HFCEHRCYVN RETERGFCRI KESYYSTEFL HLGEERVLVP
     SHTIFFCGCN FKCVFCQNWD ISQVYFDKTI PNHCIPYNPK EMAKIIKHKR DYSKNVNFVG
     GDPTPHLLSI LKTLSYLDKN IPVVWNSNMY LTVEGMHLLK GVVDVYLTDF KFGNNECGER
     LSKVKNYFDI IKRNHLLIKD EEVIIRHLVM PNHLDCCTEK IFDFISKNLD NAVVNVMFQY
     RPEYKAKEYP DINRRLTYEE IEKALELAEK YNLDLIYD