ID   Y680_EXIS2              Reviewed;         378 AA.
AC   B1YK80;
DT   03-NOV-2009, integrated into UniProtKB/Swiss-Prot.
DT   20-MAY-2008, sequence version 1.
DT   25-MAY-2022, entry version 73.
DE   RecName: Full=UPF0754 membrane protein Exig_0680;
GN   OrderedLocusNames=Exig_0680;
OS   Exiguobacterium sibiricum (strain DSM 17290 / CIP 109462 / JCM 13490 /
OS   255-15).
OC   Bacteria; Firmicutes; Bacilli; Bacillales;
OC   Bacillales Family XII. Incertae Sedis; Exiguobacterium.
OX   NCBI_TaxID=262543;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 17290 / CIP 109462 / JCM 13490 / 255-15;
RG   US DOE Joint Genome Institute;
RA   Copeland A., Lucas S., Lapidus A., Glavina del Rio T., Dalin E., Tice H.,
RA   Bruce D., Goodwin L., Pitluck S., Kiss H., Chertkov O., Monk C.,
RA   Brettin T., Detter J.C., Han C., Kuske C.R., Schmutz J., Larimer F.,
RA   Land M., Hauser L., Kyrpides N., Mikhailova N., Vishnivetskaya T.,
RA   Rodrigues D.F., Gilichinsky D., Tiedje J., Richardson P.;
RT   "Complete sequence of chromosome of Exiguobacterium sibiricum 255-15.";
RL   Submitted (APR-2008) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000250}; Multi-pass membrane
CC       protein {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the UPF0754 family. {ECO:0000305}.
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DR   EMBL; CP001022; ACB60161.1; -; Genomic_DNA.
DR   RefSeq; WP_012369585.1; NC_010556.1.
DR   AlphaFoldDB; B1YK80; -.
DR   SMR; B1YK80; -.
DR   STRING; 262543.Exig_0680; -.
DR   EnsemblBacteria; ACB60161; ACB60161; Exig_0680.
DR   KEGG; esi:Exig_0680; -.
DR   eggNOG; COG4399; Bacteria.
DR   HOGENOM; CLU_042384_0_0_9; -.
DR   OMA; DTIMGSL; -.
DR   OrthoDB; 373600at2; -.
DR   Proteomes; UP000001681; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   InterPro; IPR007383; DUF445.
DR   Pfam; PF04286; DUF445; 1.
PE   3: Inferred from homology;
KW   Cell membrane; Membrane; Reference proteome; Transmembrane;
KW   Transmembrane helix.
FT   CHAIN           1..378
FT                   /note="UPF0754 membrane protein Exig_0680"
FT                   /id="PRO_0000388291"
FT   TRANSMEM        5..25
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        357..377
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   378 AA;  42725 MW;  4C418B5DDC179D3E CRC64;
     MQVEVDLVIK MIGMIVIGAL IGAVTNHLAI RMLFRPLEAK YIGKYRIPFT PGLIPKRRDE
     LAANLGRTVV KHLLTPEGIS KRLQQPIVYQ AITRMIQQEV QKWTRSTKTI REIAERFVAN
     PEGKLQQQIE QRIDQELESM AVAIKTARLT EVLGEGGTTK IKTAIPGMVE VLLHQTEQYF
     DSPAGKMKLE ETVAQFIQSK LGGGMFGMLL ANVNIVEMIQ PELKRVIQGK STHQFISEMV
     EQEVHTLLER TVGSLLEPEA ERQIIERMKS EIVTRIPLAA LLDTPLHEFL EPLEVRISQE
     MVPMLSKQMV NRLIEQVEQI MATLDLETIV REEVDLLDTA YLEEIVLSIS RREFRAITWL
     GGLLGGLIGM IQAILLIV