ID   Y680_HAEIN              Reviewed;         298 AA.
AC   Q57389; O05030;
DT   01-NOV-1997, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1996, sequence version 1.
DT   03-AUG-2022, entry version 111.
DE   RecName: Full=Uncharacterized transporter HI_0680;
GN   OrderedLocusNames=HI_0680;
OS   Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Pasteurellales;
OC   Pasteurellaceae; Haemophilus.
OX   NCBI_TaxID=71421;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 51907 / DSM 11121 / KW20 / Rd;
RX   PubMed=7542800; DOI=10.1126/science.7542800;
RA   Fleischmann R.D., Adams M.D., White O., Clayton R.A., Kirkness E.F.,
RA   Kerlavage A.R., Bult C.J., Tomb J.-F., Dougherty B.A., Merrick J.M.,
RA   McKenney K., Sutton G.G., FitzHugh W., Fields C.A., Gocayne J.D.,
RA   Scott J.D., Shirley R., Liu L.-I., Glodek A., Kelley J.M., Weidman J.F.,
RA   Phillips C.A., Spriggs T., Hedblom E., Cotton M.D., Utterback T.R.,
RA   Hanna M.C., Nguyen D.T., Saudek D.M., Brandon R.C., Fine L.D.,
RA   Fritchman J.L., Fuhrmann J.L., Geoghagen N.S.M., Gnehm C.L., McDonald L.A.,
RA   Small K.V., Fraser C.M., Smith H.O., Venter J.C.;
RT   "Whole-genome random sequencing and assembly of Haemophilus influenzae
RT   Rd.";
RL   Science 269:496-512(1995).
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Multi-pass membrane
CC       protein {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the EamA transporter family. {ECO:0000305}.
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DR   EMBL; L42023; AAC22339.1; -; Genomic_DNA.
DR   PIR; I64085; I64085.
DR   RefSeq; NP_438840.1; NC_000907.1.
DR   RefSeq; WP_010869031.1; NC_000907.1.
DR   STRING; 71421.HI_0680; -.
DR   TCDB; 2.A.7.7.3; the drug/metabolite transporter (dmt) superfamily.
DR   EnsemblBacteria; AAC22339; AAC22339; HI_0680.
DR   KEGG; hin:HI_0680; -.
DR   PATRIC; fig|71421.8.peg.711; -.
DR   eggNOG; COG2962; Bacteria.
DR   HOGENOM; CLU_054508_2_0_6; -.
DR   OMA; LMQYIEP; -.
DR   PhylomeDB; Q57389; -.
DR   BioCyc; HINF71421:G1GJ1-715-MON; -.
DR   Proteomes; UP000000579; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IBA:GO_Central.
DR   GO; GO:0005887; C:integral component of plasma membrane; IEA:InterPro.
DR   GO; GO:0005886; C:plasma membrane; IBA:GO_Central.
DR   InterPro; IPR000620; EamA_dom.
DR   InterPro; IPR004626; RarD.
DR   Pfam; PF00892; EamA; 1.
DR   TIGRFAMs; TIGR00688; rarD; 1.
PE   3: Inferred from homology;
KW   Cell membrane; Membrane; Reference proteome; Transmembrane;
KW   Transmembrane helix; Transport.
FT   CHAIN           1..298
FT                   /note="Uncharacterized transporter HI_0680"
FT                   /id="PRO_0000108159"
FT   TRANSMEM        5..23
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        33..52
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        72..91
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        101..120
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        127..145
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        149..166
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        175..194
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        207..229
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        238..260
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        265..284
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   DOMAIN          13..144
FT                   /note="EamA"
SQ   SEQUENCE   298 AA;  33465 MW;  65DC2A9EB8F9EF02 CRC64;
     MFKGILVSLL ASFLFGYMYY FSTLLKPLSG TDIFGYRMIF TFPFVLLSVT LFKQKAALIE
     RLKRIQKRPH LALSYLLCGL LMGFQMWLFL WAPNNGSSLS VSFGYLLLPI VMVAAGRVFF
     KERISTFKFI AVIIATLGVI SNIVLKGGLS WEAIVICLGY TAYFSIRKAL KNTDLASFCL
     EMLSLMPVSI YFALQTDFAT VQQTNPFIWG XLVLLGLISG TALIAYVIAS NMLPMNLLGL
     LGYVETIMML CVSFLIGEQI DSESYPLFIC LVIAMILVMV DGVYKHTQKE VYKCHLKK