ID   Y690_STRP6              Reviewed;         282 AA.
AC   Q5XCN8;
DT   30-AUG-2005, integrated into UniProtKB/Swiss-Prot.
DT   23-NOV-2004, sequence version 1.
DT   03-AUG-2022, entry version 68.
DE   RecName: Full=DegV domain-containing protein M6_Spy0690;
GN   OrderedLocusNames=M6_Spy0690;
OS   Streptococcus pyogenes serotype M6 (strain ATCC BAA-946 / MGAS10394).
OC   Bacteria; Firmicutes; Bacilli; Lactobacillales; Streptococcaceae;
OC   Streptococcus.
OX   NCBI_TaxID=286636;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC BAA-946 / MGAS10394;
RX   PubMed=15272401; DOI=10.1086/422697;
RA   Banks D.J., Porcella S.F., Barbian K.D., Beres S.B., Philips L.E.,
RA   Voyich J.M., DeLeo F.R., Martin J.M., Somerville G.A., Musser J.M.;
RT   "Progress toward characterization of the group A Streptococcus metagenome:
RT   complete genome sequence of a macrolide-resistant serotype M6 strain.";
RL   J. Infect. Dis. 190:727-738(2004).
CC   -!- FUNCTION: May bind long-chain fatty acids, such as palmitate, and may
CC       play a role in lipid transport or fatty acid metabolism. {ECO:0000250}.
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DR   EMBL; CP000003; AAT86825.1; -; Genomic_DNA.
DR   RefSeq; WP_011017667.1; NC_006086.1.
DR   AlphaFoldDB; Q5XCN8; -.
DR   SMR; Q5XCN8; -.
DR   EnsemblBacteria; AAT86825; AAT86825; M6_Spy0690.
DR   KEGG; spa:M6_Spy0690; -.
DR   HOGENOM; CLU_048251_3_1_9; -.
DR   OMA; MALGFCA; -.
DR   Proteomes; UP000001167; Chromosome.
DR   GO; GO:0008289; F:lipid binding; IEA:UniProtKB-KW.
DR   Gene3D; 3.30.1180.10; -; 1.
DR   InterPro; IPR003797; DegV.
DR   InterPro; IPR043168; DegV_C.
DR   Pfam; PF02645; DegV; 1.
DR   TIGRFAMs; TIGR00762; DegV; 1.
DR   PROSITE; PS51482; DEGV; 1.
PE   3: Inferred from homology;
KW   Lipid-binding.
FT   CHAIN           1..282
FT                   /note="DegV domain-containing protein M6_Spy0690"
FT                   /id="PRO_0000209802"
FT   DOMAIN          3..280
FT                   /note="DegV"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00815"
FT   BINDING         61
FT                   /ligand="hexadecanoate"
FT                   /ligand_id="ChEBI:CHEBI:7896"
FT                   /evidence="ECO:0000250|UniProtKB:Q9X1H9"
FT   BINDING         94
FT                   /ligand="hexadecanoate"
FT                   /ligand_id="ChEBI:CHEBI:7896"
FT                   /evidence="ECO:0000250|UniProtKB:Q9X1H9"
SQ   SEQUENCE   282 AA;  31389 MW;  D44245E9E264C710 CRC64;
     MKLAVITDST ATLPIDLKQD KAIFSLDIPV IIDDETYFEG RNLSIDDFYQ KMADSQNLPK
     TSQPSLSELD NLLGLLSSKG YTHVIGLFLA GGISGFWQNI QFLAEEHPEI EMAFPDSKIT
     SAPLGSMVKN VLDWSRQGMT FQAILNKLQE QIDRTTAFIM VDDLNHLVKG GRLSNGSALL
     GNLLSIKPIL RFDEEGKIVV YEKVRTEKKA MKRLVEILND LIADGQYNVS IIHSKAQDKA
     DYLKRLLQDS GYQYDIEEVH FGAVIATHLG EGAIAFGVTP RL