ID   Y693_TREPA              Reviewed;         440 AA.
AC   O83691;
DT   01-JUN-2001, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1998, sequence version 1.
DT   25-MAY-2022, entry version 94.
DE   RecName: Full=Uncharacterized lipoprotein TP_0693;
DE   Flags: Precursor;
GN   OrderedLocusNames=TP_0693;
OS   Treponema pallidum (strain Nichols).
OC   Bacteria; Spirochaetes; Spirochaetales; Treponemataceae; Treponema.
OX   NCBI_TaxID=243276;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Nichols;
RX   PubMed=9665876; DOI=10.1126/science.281.5375.375;
RA   Fraser C.M., Norris S.J., Weinstock G.M., White O., Sutton G.G.,
RA   Dodson R.J., Gwinn M.L., Hickey E.K., Clayton R.A., Ketchum K.A.,
RA   Sodergren E., Hardham J.M., McLeod M.P., Salzberg S.L., Peterson J.D.,
RA   Khalak H.G., Richardson D.L., Howell J.K., Chidambaram M., Utterback T.R.,
RA   McDonald L.A., Artiach P., Bowman C., Cotton M.D., Fujii C., Garland S.A.,
RA   Hatch B., Horst K., Roberts K.M., Sandusky M., Weidman J.F., Smith H.O.,
RA   Venter J.C.;
RT   "Complete genome sequence of Treponema pallidum, the syphilis spirochete.";
RL   Science 281:375-388(1998).
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000255|PROSITE-
CC       ProRule:PRU00303}; Lipid-anchor {ECO:0000255|PROSITE-ProRule:PRU00303}.
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DR   EMBL; AE000520; AAC65665.1; -; Genomic_DNA.
DR   PIR; B71293; B71293.
DR   RefSeq; WP_010882138.1; NC_021490.2.
DR   AlphaFoldDB; O83691; -.
DR   IntAct; O83691; 1.
DR   STRING; 243276.TPANIC_0693; -.
DR   EnsemblBacteria; AAC65665; AAC65665; TP_0693.
DR   GeneID; 57879219; -.
DR   KEGG; tpa:TP_0693; -.
DR   eggNOG; ENOG5031CGG; Bacteria.
DR   HOGENOM; CLU_622461_0_0_12; -.
DR   OMA; WRCVLFA; -.
DR   OrthoDB; 805997at2; -.
DR   Proteomes; UP000000811; Chromosome.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   PROSITE; PS51257; PROKAR_LIPOPROTEIN; 1.
PE   3: Inferred from homology;
KW   Cell membrane; Lipoprotein; Membrane; Palmitate; Reference proteome;
KW   Signal.
FT   SIGNAL          1..17
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00303"
FT   CHAIN           18..440
FT                   /note="Uncharacterized lipoprotein TP_0693"
FT                   /id="PRO_0000014254"
FT   REGION          241..268
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   LIPID           18
FT                   /note="N-palmitoyl cysteine"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00303"
FT   LIPID           18
FT                   /note="S-diacylglycerol cysteine"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00303"
SQ   SEQUENCE   440 AA;  47673 MW;  B6B3BE24EBB66065 CRC64;
     MDRFFCTVWV WSVLFGACTS QTRSSFSLNA DGLNSSGVAH ASEHVSHAAA MGNEAGAADA
     SVSESPASFS PGRGSAWVQG TVGHIPAEHH AALQAFFDTE EGMRITDALC TGDTYAAFNE
     LEALYDPSSE TDTARSRALH AYVRALLQGI RLAPRVAPPT HVGVSATLQY RDSVWPLQRG
     RFTLCYQIGP EHGDVMQVTL CADTQGVLFF PFPSAALSQE VTLSFDTAAL VHAPSLCAQD
     SALQERPSSP EPVVSTIPSP EGEENSAAGE PALANLVCRV AAPSSDPKQH PVRRQVSTTI
     CILDYGKTGR PLTHENLTAT RLLGGLLKRR FVNIGLDSLY GVGKVPDHAV IARARKKFGG
     NVRRLVFGLT QVRRLERDSD ARWKCVLFAQ LHVWDFPKGA YTHHFTAQCT ETGDTESQSY
     VRARTRMGET VLSDVLQCFL