ID   Y6940_STRAW             Reviewed;         274 AA.
AC   Q827I4;
DT   07-JUN-2004, integrated into UniProtKB/Swiss-Prot.
DT   01-JUN-2003, sequence version 1.
DT   25-MAY-2022, entry version 83.
DE   RecName: Full=Putative hydro-lyase SAV_6940 {ECO:0000255|HAMAP-Rule:MF_01830};
DE            EC=4.2.1.- {ECO:0000255|HAMAP-Rule:MF_01830};
GN   OrderedLocusNames=SAV_6940;
OS   Streptomyces avermitilis (strain ATCC 31267 / DSM 46492 / JCM 5070 / NBRC
OS   14893 / NCIMB 12804 / NRRL 8165 / MA-4680).
OC   Bacteria; Actinobacteria; Streptomycetales; Streptomycetaceae;
OC   Streptomyces.
OX   NCBI_TaxID=227882;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 31267 / DSM 46492 / JCM 5070 / NBRC 14893 / NCIMB 12804 / NRRL
RC   8165 / MA-4680;
RX   PubMed=11572948; DOI=10.1073/pnas.211433198;
RA   Omura S., Ikeda H., Ishikawa J., Hanamoto A., Takahashi C., Shinose M.,
RA   Takahashi Y., Horikawa H., Nakazawa H., Osonoe T., Kikuchi H., Shiba T.,
RA   Sakaki Y., Hattori M.;
RT   "Genome sequence of an industrial microorganism Streptomyces avermitilis:
RT   deducing the ability of producing secondary metabolites.";
RL   Proc. Natl. Acad. Sci. U.S.A. 98:12215-12220(2001).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 31267 / DSM 46492 / JCM 5070 / NBRC 14893 / NCIMB 12804 / NRRL
RC   8165 / MA-4680;
RX   PubMed=12692562; DOI=10.1038/nbt820;
RA   Ikeda H., Ishikawa J., Hanamoto A., Shinose M., Kikuchi H., Shiba T.,
RA   Sakaki Y., Hattori M., Omura S.;
RT   "Complete genome sequence and comparative analysis of the industrial
RT   microorganism Streptomyces avermitilis.";
RL   Nat. Biotechnol. 21:526-531(2003).
CC   -!- SIMILARITY: Belongs to the D-glutamate cyclase family.
CC       {ECO:0000255|HAMAP-Rule:MF_01830}.
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DR   EMBL; BA000030; BAC74651.1; -; Genomic_DNA.
DR   RefSeq; WP_010988337.1; NZ_JZJK01000082.1.
DR   AlphaFoldDB; Q827I4; -.
DR   SMR; Q827I4; -.
DR   STRING; 227882.SAV_6940; -.
DR   EnsemblBacteria; BAC74651; BAC74651; SAVERM_6940.
DR   KEGG; sma:SAVERM_6940; -.
DR   eggNOG; COG4336; Bacteria.
DR   HOGENOM; CLU_059759_0_0_11; -.
DR   OMA; NVPMYKT; -.
DR   OrthoDB; 1432388at2; -.
DR   Proteomes; UP000000428; Chromosome.
DR   GO; GO:0016829; F:lyase activity; IEA:UniProtKB-KW.
DR   HAMAP; MF_01830; Hydro_lyase; 1.
DR   InterPro; IPR009906; D-Glu_cyclase.
DR   InterPro; IPR038021; Putative_hydro-lyase.
DR   InterPro; IPR016938; UPF0317.
DR   Pfam; PF07286; DUF1445; 1.
DR   PIRSF; PIRSF029755; UCP029755; 1.
DR   SUPFAM; SSF160920; SSF160920; 1.
PE   3: Inferred from homology;
KW   Lyase; Reference proteome.
FT   CHAIN           1..274
FT                   /note="Putative hydro-lyase SAV_6940"
FT                   /id="PRO_0000217172"
SQ   SEQUENCE   274 AA;  30030 MW;  9D96190002CD6AD5 CRC64;
     MNRVTPDRPL SRIDGHAHAW TPRKARARFR WGVFGPTAGV AAGHTQANLI SLPADWAYDM
     LLFCQRNPKP CPVLDVTDAG SWTTPLAEGA DLRTDLPRYR VWENGELVAE PTDVVAYWRD
     DLVSFLIGCS FTFEWALSEA GVPMRHIEQG RNVSMYVTSR ACRPAGRLHG PMVVSMRPVP
     PEHLAAAIRE STMLPAVHGS PVHCGDPSGL GIDDLGRPDF GDPVDAEPDD IPVFWACGVT
     PQAAVMASRP PFAITHAPGQ MFLTDARDEQ YRVA