Y6969_DICDI
ID Y6969_DICDI Reviewed; 2079 AA.
AC C7G046;
DT 24-NOV-2009, integrated into UniProtKB/Swiss-Prot.
DT 13-OCT-2009, sequence version 1.
DT 25-MAY-2022, entry version 56.
DE RecName: Full=von Willebrand factor A domain-containing protein DDB_G0286969;
GN ORFNames=DDB_G0286969;
OS Dictyostelium discoideum (Slime mold).
OC Eukaryota; Amoebozoa; Evosea; Eumycetozoa; Dictyostelia; Dictyosteliales;
OC Dictyosteliaceae; Dictyostelium.
OX NCBI_TaxID=44689;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=AX4;
RX PubMed=15875012; DOI=10.1038/nature03481;
RA Eichinger L., Pachebat J.A., Gloeckner G., Rajandream M.A., Sucgang R.,
RA Berriman M., Song J., Olsen R., Szafranski K., Xu Q., Tunggal B.,
RA Kummerfeld S., Madera M., Konfortov B.A., Rivero F., Bankier A.T.,
RA Lehmann R., Hamlin N., Davies R., Gaudet P., Fey P., Pilcher K., Chen G.,
RA Saunders D., Sodergren E.J., Davis P., Kerhornou A., Nie X., Hall N.,
RA Anjard C., Hemphill L., Bason N., Farbrother P., Desany B., Just E.,
RA Morio T., Rost R., Churcher C.M., Cooper J., Haydock S., van Driessche N.,
RA Cronin A., Goodhead I., Muzny D.M., Mourier T., Pain A., Lu M., Harper D.,
RA Lindsay R., Hauser H., James K.D., Quiles M., Madan Babu M., Saito T.,
RA Buchrieser C., Wardroper A., Felder M., Thangavelu M., Johnson D.,
RA Knights A., Loulseged H., Mungall K.L., Oliver K., Price C., Quail M.A.,
RA Urushihara H., Hernandez J., Rabbinowitsch E., Steffen D., Sanders M.,
RA Ma J., Kohara Y., Sharp S., Simmonds M.N., Spiegler S., Tivey A.,
RA Sugano S., White B., Walker D., Woodward J.R., Winckler T., Tanaka Y.,
RA Shaulsky G., Schleicher M., Weinstock G.M., Rosenthal A., Cox E.C.,
RA Chisholm R.L., Gibbs R.A., Loomis W.F., Platzer M., Kay R.R.,
RA Williams J.G., Dear P.H., Noegel A.A., Barrell B.G., Kuspa A.;
RT "The genome of the social amoeba Dictyostelium discoideum.";
RL Nature 435:43-57(2005).
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DR EMBL; AAFI02000092; EEU04074.1; -; Genomic_DNA.
DR RefSeq; XP_002649126.1; XM_002649080.1.
DR AlphaFoldDB; C7G046; -.
DR SMR; C7G046; -.
DR STRING; 44689.DDB0252861; -.
DR PaxDb; C7G046; -.
DR EnsemblProtists; EEU04074; EEU04074; DDB_G0286969.
DR GeneID; 8625857; -.
DR KEGG; ddi:DDB_G0286969; -.
DR dictyBase; DDB_G0286969; -.
DR eggNOG; KOG0401; Eukaryota.
DR HOGENOM; CLU_232704_0_0_1; -.
DR InParanoid; C7G046; -.
DR OMA; FPIGMGE; -.
DR PRO; PR:C7G046; -.
DR Proteomes; UP000002195; Chromosome 4.
DR GO; GO:0003723; F:RNA binding; IEA:InterPro.
DR Gene3D; 3.40.50.410; -; 1.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR003891; Initiation_fac_eIF4g_MI.
DR InterPro; IPR003890; MIF4G-like_typ-3.
DR InterPro; IPR013694; VIT.
DR InterPro; IPR002035; VWF_A.
DR InterPro; IPR036465; vWFA_dom_sf.
DR Pfam; PF02847; MA3; 1.
DR Pfam; PF02854; MIF4G; 1.
DR Pfam; PF08487; VIT; 1.
DR Pfam; PF13768; VWA_3; 1.
DR SMART; SM00544; MA3; 1.
DR SMART; SM00543; MIF4G; 1.
DR SMART; SM00327; VWA; 1.
DR SUPFAM; SSF48371; SSF48371; 2.
DR SUPFAM; SSF53300; SSF53300; 1.
DR PROSITE; PS51366; MI; 1.
DR PROSITE; PS51468; VIT; 1.
DR PROSITE; PS50234; VWFA; 1.
PE 4: Predicted;
KW Coiled coil; Reference proteome.
FT CHAIN 1..2079
FT /note="von Willebrand factor A domain-containing protein
FT DDB_G0286969"
FT /id="PRO_0000389214"
FT DOMAIN 11..147
FT /note="VIT"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00801"
FT DOMAIN 354..525
FT /note="VWFA"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00219"
FT DOMAIN 1317..1527
FT /note="MIF4G"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00698"
FT DOMAIN 1760..1882
FT /note="MI"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00698"
FT REGION 178..203
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 761..800
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 832..866
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 956..1139
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1155..1203
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1239..1294
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1530..1755
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 923..957
FT /evidence="ECO:0000255"
FT COMPBIAS 837..866
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 961..977
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1005..1021
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1036..1066
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1239..1272
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1273..1291
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1534..1600
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1639..1657
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1683..1727
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 2079 AA; 227899 MW; 3B2A96B3F878357E CRC64;
MYSGLWTKNG EQILPSFISI NAKVVDLAAQ IVFTKTYSDI NKYFATMNKM NSSNEEDATF
KAFLNTSMGV LCGFEINLDG KKITSQVVSQ ADAMRLFEKN QISTADDIVK EAEFNNSDPH
IEEDFFLCKV NNLSQYKELE IIITYSTEMS TQGDYLFMEF PTSLTTIRSS QFFETLDNEN
STTNTNTQTQ PQSVNTTTTT TPSTTTATNI TNINNNIQNI GSSTTGGLTH STSSNKLSLS
SSSIQVNQKQ GLLIEMNLDM PSKISEIISP SHSGLIDVEY KGETGKVTYK DSRSIDVVNQ
SDLVVLIKLD NPHEPYGFIE ENENGSRALM IAFYPQLSSA AIAASATTPV VESELIFLVD
VSESMEGYNM KHAKKALHRF LHSLSKDTYF NIISFASSHR KLFAQSVKYN DENLKAATAY
VESLKAISHG ETNLLEPLKD IYSVDATCPR KIFLLTDGRV NNIGPIVDLV RQNAHNTSVF
PIGMGEFVSR QLVEYIANAG SGVAELVIEN ETIESKVMRQ LKRALQPAMS NIKVDWGSLS
SKSQAPRDLR TLFFGDRLTI YNILGKDEKI DGTTVKLIAN GPTGPVSFPV TIKSEETKKG
NLVHSLAAYT LIQDLQDQIY ENNLVDPKDI DPIRQKIIDL GIKYGLASNY TSFCSVEQPD
QFNELLNNNK QSEQAQETTT TTTTATTVDD NVVIEENKQP EPIVEEQPPV LNGNINLQNL
TINHDGKSND NGLFKSNDRL KTHHQGESAM ISLRGSASGI PTTLSGSGIP FYNPSSPNHD
RNINTTQQPT PTQSTPLKTP LKTPLTPLSK SGLKVSSPEF VPKNTLSAKA APFVPSPNKL
PTTTTSAPAT TPITTPAPTT TTTEVKPTVA EPVKPVVAEP TKPVVAEPTI PAVAEPIKPV
VTEPTKPVVE EPAKPAVKPT LFEMIKIAEA KAAAEQKAAA EQKAIADAKA AAEQAAKPVE
PAVVQQQQPQ QTKPKADKQS KQNAKDNKQS NKPVVVEQKP PVVTETKPTV ATESATPTKP
TFAQAAAAAA AAAQQAAQQA AATTPVKQQP TKQTTPNKST PAVETKSVVA ETKPAVEQPK
PVETKPVVEQ PKPVETKPVE QTKPVETKPV EVKPTVEQPK PVEVKPTVEQ PKPIETKPTV
NSIASTLANF GFQTNEPAKQ ATPTPAPTPV QSNESNNNNN NNNNNNNNNN NNNNNNNNIV
SSTPIKKPAV TNILPTQAVI LSSGGRRVYN NDFLLSFKDS NTKAPDSLKT TPIFSNGPQG
ISPSSGNGSN KSHFGKKRGD RGGRGGRDRN ADAEPSTPII VKKVFSQDVQ GTHQELLKKF
KFNLNRITMD TYSSLIKNID ELKVPDEEAL KSISKILFEK AIIDQKYSAV YAILAGHLDT
TFPKFAELSL KRAILDNCQT EFSAVVDKSK FEGLSKEDLE EQEFIIKRRV LGNIKFIGEL
YKHGVLGEKV AKAIVVQLIT KCEERLDEES IEPLVKILNT IGKKLDEVDK ANTDLYFSKV
TNISNNPVVT SRGRFILLDL IDLRANKWQP KNSTQTKTKK DESDKEERFI AKHGGPQKRE
NDSRRDGGRD SRGDDRRGGG GRDSRGDDRR GGRDSRDAPR SAFGGKSSKD GWETVGAKGG
NNRDKGGRGG DRSGGKQSPS GKKDSGFGPS SGGSSLFGSR RGDDRRDGGG NSSPYRPGQG
FGRKDDQSSS IPSIPNRSNA FSALEDDDYQ PSTSPQPPSV FGNRSNDRDS RGPSKPDNRK
QPAQPPAPVE PVKPKINFEK IEDDISMTLD EYAETQDIDE AIECIKEINE PTVLGKQFNI
FIMKSLERKE KEKQLIIELF SGILTAQLFN AEQIKEGLKE IIDTIEDIEI DLPFSGVFVA
TIVGICIESE IFPLNYLEEA YAHLVDSDKA EEMIVNTFNS IVKVSDKDRL VEIYENTKGL
DILKLFALKN RKVAYLEEFY QTHFPYLSHE KAVEGSNESA LNEQPDLIEH LLLLQSADGY
WQLDKKLAGI LGISLNILEE VDSSDSCVIT THPEVWATCL AITFVNLNNV SDPDDEDDLE
LVLSKSHKWL ASQYQSDKPP KQSQDDVLLK AKRLLSEVL
