Y6997_DICDI
ID Y6997_DICDI Reviewed; 1650 AA.
AC P0CD64;
DT 09-FEB-2010, integrated into UniProtKB/Swiss-Prot.
DT 09-FEB-2010, sequence version 1.
DT 25-MAY-2022, entry version 32.
DE RecName: Full=Transmembrane domain-containing protein DDB_G0287209;
GN ORFNames=DDB_G0287209;
OS Dictyostelium discoideum (Slime mold).
OC Eukaryota; Amoebozoa; Evosea; Eumycetozoa; Dictyostelia; Dictyosteliales;
OC Dictyosteliaceae; Dictyostelium.
OX NCBI_TaxID=44689;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=AX4;
RX PubMed=15875012; DOI=10.1038/nature03481;
RA Eichinger L., Pachebat J.A., Gloeckner G., Rajandream M.A., Sucgang R.,
RA Berriman M., Song J., Olsen R., Szafranski K., Xu Q., Tunggal B.,
RA Kummerfeld S., Madera M., Konfortov B.A., Rivero F., Bankier A.T.,
RA Lehmann R., Hamlin N., Davies R., Gaudet P., Fey P., Pilcher K., Chen G.,
RA Saunders D., Sodergren E.J., Davis P., Kerhornou A., Nie X., Hall N.,
RA Anjard C., Hemphill L., Bason N., Farbrother P., Desany B., Just E.,
RA Morio T., Rost R., Churcher C.M., Cooper J., Haydock S., van Driessche N.,
RA Cronin A., Goodhead I., Muzny D.M., Mourier T., Pain A., Lu M., Harper D.,
RA Lindsay R., Hauser H., James K.D., Quiles M., Madan Babu M., Saito T.,
RA Buchrieser C., Wardroper A., Felder M., Thangavelu M., Johnson D.,
RA Knights A., Loulseged H., Mungall K.L., Oliver K., Price C., Quail M.A.,
RA Urushihara H., Hernandez J., Rabbinowitsch E., Steffen D., Sanders M.,
RA Ma J., Kohara Y., Sharp S., Simmonds M.N., Spiegler S., Tivey A.,
RA Sugano S., White B., Walker D., Woodward J.R., Winckler T., Tanaka Y.,
RA Shaulsky G., Schleicher M., Weinstock G.M., Rosenthal A., Cox E.C.,
RA Chisholm R.L., Gibbs R.A., Loomis W.F., Platzer M., Kay R.R.,
RA Williams J.G., Dear P.H., Noegel A.A., Barrell B.G., Kuspa A.;
RT "The genome of the social amoeba Dictyostelium discoideum.";
RL Nature 435:43-57(2005).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Multi-pass membrane
CC protein {ECO:0000305}.
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DR EMBL; AAFI02000097; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AAFI02000098; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; P0CD64; -.
DR dictyBase; DDB_G0287209; -.
DR InParanoid; P0CD64; -.
DR PhylomeDB; P0CD64; -.
DR PRO; PR:P0CD64; -.
DR Proteomes; UP000002195; Chromosome 4.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR InterPro; IPR011050; Pectin_lyase_fold/virulence.
DR SUPFAM; SSF51126; SSF51126; 1.
PE 4: Predicted;
KW Coiled coil; Membrane; Reference proteome; Transmembrane;
KW Transmembrane helix.
FT CHAIN 1..1650
FT /note="Transmembrane domain-containing protein
FT DDB_G0287209"
FT /id="PRO_0000391337"
FT TRANSMEM 1314..1334
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 1347..1369
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 1390..1410
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 1454..1474
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 1489..1509
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 1515..1535
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 1539..1559
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 1570..1590
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 1595..1615
FT /note="Helical"
FT /evidence="ECO:0000255"
FT REGION 197..216
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1218..1296
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 194..225
FT /evidence="ECO:0000255"
FT COMPBIAS 1222..1282
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1650 AA; 188351 MW; 0254AF5E03248404 CRC64;
MIDIIDYNFN NHIKNDNSKF NNILKKYQIN NNTFENGAIL DLNDIGSNIL YKNEDKEKDE
EEYYYYKENQ NIYNKIGNDL NYNFQYNEYI ENNDFENNQP IDNFNVEGSG GGKQIISYYL
SKNGNDTTGN GTINSPYLSI CKIVNIINSY NGINIFKVFI EIGNYEAVEG CTLNIINNSV
VSLIYFTKNE IINNNNNNNF NNNNNNNNNN NNNKNNYNNN KSNLIIPNII NLNINLKNST
FFLNYINLHY FNEKVINITY GINTFQFLIE NSNLHCVNPK LPYCNILFNK LNQSLIINDD
NEAMILIKNS NIIKFDFYFN IIEMNVENSN LYFTSLYSLI SQNLTFSKSY FNNTLIYLVE
YQAINVSIDH CKMIYDFSNN IQVFLMGTGN ILTISNSQME STGEFFSSYI TCKNAKVQLM
NVQFINWYLL RPFINLSLNS TLIMENVFAR KMYIPAFIEI GNSELIIDTL EISGNKLVLI
IIEGPSVISI SYLTLKYQSE QGSPIMMNFP GGGFGMKTII NITSSNFINI DGFTLKDAQL
TLFNVSMHSD SINSLFALSS SQLFSSKSTF SSSLIVGSYF LFSLDFTSLV DLDRCILTNS
SSLFQANSFS NITITNSLID SVFSRSVAIE IQGGSSFTMI NSIINKTYVV SQSFIYSSSN
SDIIIHKCNF LQFVMGLKPL GNFLNSNVFI DHLLLYQSFF QNQIFVATSS IMYISDTKLF
NNSIYGSEMF LLNNQSYLLM NNSLIYGNSI SVCFSSSHSL ANIHNVTFQN NSGIFLYSVD
SKISLSLLEF SKNPISSLYY LFYFTNSSAT FQQLTIDSNY FMGSVIEAHF SEILFTNLIF
SLNQNVDNLL KDRESPSLVF THSNVKIINS TINSNSQWSL DLIWSQKSIL IIKNSLFNSN
SIPYNGYLIR LETCHLSLDH CLIFGTQSIE GTIGSFNSII NATNNLFLQN NALEMGGCFF
LSNSQILSFS NNSFLNNTAS IGAAIFTNGT LINNTLIIKS NKFLNNNAYE YGDNIGSYPT
WISVEYPEDF DSTINYIRLY DNYSNLVADN FYTANIIIYD SRVNENISLT TFIRGGSGDF
NYSFNVFSIY DFQISINIIA DGFNINYLKY KSPPKCLNFQ TSTLSDGCIF CPINQAATPE
KGECTKCDTN KLVCLNNDVH TLQDYFMINN DVSKVYQCPF GLCSGQNNCN SNLFLLSSLQ
SPLCSRCLND YNNENDDENQ FKYNNNENSG SSGNSNNNEN SNSNSDSNSN SNSNSNSNSN
SNSNSNSNSN SNSNSNSNEN NYNGGDDDDD EKNINNYKPS KSKNGLYCCN KFQPLLLIPF
IFWILFFGLF LSLFKNVITG TMIGQIILFL QLNSIVFYPL PNIYGLQLFR MSIDYFDRYC
LFKLDYIEKI SISLISIFLI YLIGISDVTS RLILSILKRS LKLKKLIPLV IEKQLRKFEY
YKMNRINTRL KSNWNIYLML IQPLFHCLIS LIVPKSIGST TYLSIDLTIL FISTPIQIVF
FFSSIVILFL LEFRWWDLIF VFKTILFTSL SVTLLYNPPV YFSALVICQI VYSYSQFAFS
PQRKDHMYRV ENLLNLFQLS ILIVINTSII RNLSFNLIGI LFTIVIFSCS LITIIYKLFF
YKKLKTIKNH RLLNLIINVD DNKKKTNKNK
