Y708_STAAW
ID Y708_STAAW Reviewed; 356 AA.
AC Q7A1G8;
DT 15-MAY-2007, integrated into UniProtKB/Swiss-Prot.
DT 05-JUL-2004, sequence version 1.
DT 25-MAY-2022, entry version 96.
DE RecName: Full=Uncharacterized membrane protein MW0708;
GN OrderedLocusNames=MW0708;
OS Staphylococcus aureus (strain MW2).
OC Bacteria; Firmicutes; Bacilli; Bacillales; Staphylococcaceae;
OC Staphylococcus.
OX NCBI_TaxID=196620;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MW2;
RX PubMed=12044378; DOI=10.1016/s0140-6736(02)08713-5;
RA Baba T., Takeuchi F., Kuroda M., Yuzawa H., Aoki K., Oguchi A., Nagai Y.,
RA Iwama N., Asano K., Naimi T., Kuroda H., Cui L., Yamamoto K., Hiramatsu K.;
RT "Genome and virulence determinants of high virulence community-acquired
RT MRSA.";
RL Lancet 359:1819-1827(2002).
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Multi-pass membrane
CC protein {ECO:0000305}.
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DR EMBL; BA000033; BAB94573.1; -; Genomic_DNA.
DR RefSeq; WP_000460983.1; NC_003923.1.
DR AlphaFoldDB; Q7A1G8; -.
DR SMR; Q7A1G8; -.
DR EnsemblBacteria; BAB94573; BAB94573; BAB94573.
DR KEGG; sam:MW0708; -.
DR HOGENOM; CLU_000445_11_1_9; -.
DR OMA; HGAWKDL; -.
DR Proteomes; UP000000418; Chromosome.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0000155; F:phosphorelay sensor kinase activity; IEA:InterPro.
DR GO; GO:0071555; P:cell wall organization; IEA:InterPro.
DR CDD; cd01949; GGDEF; 1.
DR Gene3D; 3.30.70.270; -; 1.
DR InterPro; IPR000160; GGDEF_dom.
DR InterPro; IPR029787; Nucleotide_cyclase.
DR InterPro; IPR043128; Rev_trsase/Diguanyl_cyclase.
DR InterPro; IPR011620; Sig_transdc_His_kinase_LytS_TM.
DR Pfam; PF07694; 5TM-5TMR_LYT; 1.
DR Pfam; PF00990; GGDEF; 1.
DR SMART; SM00267; GGDEF; 1.
DR SUPFAM; SSF55073; SSF55073; 1.
DR TIGRFAMs; TIGR00254; GGDEF; 1.
DR PROSITE; PS50887; GGDEF; 1.
PE 4: Predicted;
KW Cell membrane; Membrane; Transmembrane; Transmembrane helix.
FT CHAIN 1..356
FT /note="Uncharacterized membrane protein MW0708"
FT /id="PRO_0000286957"
FT TRANSMEM 2..22
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 35..55
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 74..94
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 99..119
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 124..144
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 154..174
FT /note="Helical"
FT /evidence="ECO:0000255"
FT DOMAIN 218..353
FT /note="GGDEF"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00095"
SQ SEQUENCE 356 AA; 40345 MW; E687E1CD5FFA8989 CRC64;
MFEAFIYNIS VIVAGIYLFH RLQYSENKRM VFSKAYVTVL MTIVSLLLSV YPIPYREDYL
IHLTFVPLLF LGRFTNMVYT LSATVIVAIV EIVVFNNSIM YGVTLIVIAA VTSAIGPFLK
QNDVLSLLIL NVVTIIILFG VALVSPIYTL SEVIILIPIS LIITLASAIT FVDIWHFFSL
VNRYENEDKY DYLTGLGNVK EFDRHLNEIS RKAEKEHQSI ALLLIDIDGF KDVNDTYSHK
SGDAVLKQMS QLLKNYVPNQ FKIFRNGGEE FSVVIHNYSL DQSVKLAENI RSGVEKSSFH
LPNKEVIKLS VSIGVGYLTD DDPKSQRKVF KDADDMVHVA KNQGRNKVMF NPIINL