ID   Y713_STRP8              Reviewed;         296 AA.
AC   Q8P1T8;
DT   23-APR-2003, integrated into UniProtKB/Swiss-Prot.
DT   01-OCT-2002, sequence version 1.
DT   03-AUG-2022, entry version 93.
DE   RecName: Full=Nucleotide-binding protein spyM18_0713 {ECO:0000255|HAMAP-Rule:MF_00636};
GN   OrderedLocusNames=spyM18_0713;
OS   Streptococcus pyogenes serotype M18 (strain MGAS8232).
OC   Bacteria; Firmicutes; Bacilli; Lactobacillales; Streptococcaceae;
OC   Streptococcus.
OX   NCBI_TaxID=186103;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=MGAS8232;
RX   PubMed=11917108; DOI=10.1073/pnas.062526099;
RA   Smoot J.C., Barbian K.D., Van Gompel J.J., Smoot L.M., Chaussee M.S.,
RA   Sylva G.L., Sturdevant D.E., Ricklefs S.M., Porcella S.F., Parkins L.D.,
RA   Beres S.B., Campbell D.S., Smith T.M., Zhang Q., Kapur V., Daly J.A.,
RA   Veasy L.G., Musser J.M.;
RT   "Genome sequence and comparative microarray analysis of serotype M18 group
RT   A Streptococcus strains associated with acute rheumatic fever outbreaks.";
RL   Proc. Natl. Acad. Sci. U.S.A. 99:4668-4673(2002).
CC   -!- FUNCTION: Displays ATPase and GTPase activities. {ECO:0000255|HAMAP-
CC       Rule:MF_00636}.
CC   -!- SIMILARITY: Belongs to the RapZ-like family. {ECO:0000255|HAMAP-
CC       Rule:MF_00636}.
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DR   EMBL; AE009949; AAL97384.1; -; Genomic_DNA.
DR   RefSeq; WP_011017560.1; NC_003485.1.
DR   AlphaFoldDB; Q8P1T8; -.
DR   SMR; Q8P1T8; -.
DR   KEGG; spm:spyM18_0713; -.
DR   HOGENOM; CLU_059558_0_0_9; -.
DR   OMA; TVMSFGF; -.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0005525; F:GTP binding; IEA:UniProtKB-UniRule.
DR   Gene3D; 3.40.50.300; -; 1.
DR   HAMAP; MF_00636; RapZ_like; 1.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR005337; RapZ-like.
DR   PANTHER; PTHR30448; PTHR30448; 1.
DR   Pfam; PF03668; ATP_bind_2; 1.
DR   PIRSF; PIRSF005052; P-loopkin; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
PE   3: Inferred from homology;
KW   ATP-binding; GTP-binding; Nucleotide-binding.
FT   CHAIN           1..296
FT                   /note="Nucleotide-binding protein spyM18_0713"
FT                   /id="PRO_0000107775"
FT   BINDING         13..20
FT                   /ligand="ATP"
FT                   /ligand_id="ChEBI:CHEBI:30616"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00636"
FT   BINDING         63..66
FT                   /ligand="GTP"
FT                   /ligand_id="ChEBI:CHEBI:37565"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00636"
SQ   SEQUENCE   296 AA;  33617 MW;  45EC7168932811C3 CRC64;
     MSDKHINLVI VTGMSGAGKT VAIQSFEDLG YFTIDNMPPA LVPKFLELIE QTNENRRVAL
     VVDMRSRLFF KEINSTLDSI ESNPSIDFWI LFLDATDGEL VSRYKETRRS HPLAADGRVL
     DGIRLERELL SPLKSMSQHV VDTTKLTPRQ LRKTISDQFS EGSNQASFRI EVMSFGFKYG
     LPLDADLVFD VRFLPNPYYQ VELREKTGLD EDVFNYVMSH PESEVFYKHL LNLIVPILPA
     YQKEGKSVLT VAIGCTGGQH RSVAFAHCLA ESLATDWSVN ESHRDQNRRK ETVNRS