Y718_BRUME
ID Y718_BRUME Reviewed; 249 AA.
AC P65955; Q8YHS8;
DT 11-OCT-2004, integrated into UniProtKB/Swiss-Prot.
DT 11-OCT-2004, sequence version 1.
DT 03-AUG-2022, entry version 84.
DE RecName: Full=UPF0758 protein BMEI0718;
GN OrderedLocusNames=BMEI0718;
OS Brucella melitensis biotype 1 (strain 16M / ATCC 23456 / NCTC 10094).
OC Bacteria; Proteobacteria; Alphaproteobacteria; Hyphomicrobiales;
OC Brucellaceae; Brucella/Ochrobactrum group; Brucella.
OX NCBI_TaxID=224914;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=16M / ATCC 23456 / NCTC 10094;
RX PubMed=11756688; DOI=10.1073/pnas.221575398;
RA DelVecchio V.G., Kapatral V., Redkar R.J., Patra G., Mujer C., Los T.,
RA Ivanova N., Anderson I., Bhattacharyya A., Lykidis A., Reznik G.,
RA Jablonski L., Larsen N., D'Souza M., Bernal A., Mazur M., Goltsman E.,
RA Selkov E., Elzer P.H., Hagius S., O'Callaghan D., Letesson J.-J.,
RA Haselkorn R., Kyrpides N.C., Overbeek R.;
RT "The genome sequence of the facultative intracellular pathogen Brucella
RT melitensis.";
RL Proc. Natl. Acad. Sci. U.S.A. 99:443-448(2002).
CC -!- SIMILARITY: Belongs to the UPF0758 family. {ECO:0000305}.
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DR EMBL; AE008917; AAL51899.1; -; Genomic_DNA.
DR PIR; AH3341; AH3341.
DR RefSeq; WP_002964401.1; NZ_GG703780.1.
DR AlphaFoldDB; P65955; -.
DR SMR; P65955; -.
DR STRING; 224914.BMEI0718; -.
DR EnsemblBacteria; AAL51899; AAL51899; BMEI0718.
DR GeneID; 45052312; -.
DR GeneID; 55590952; -.
DR KEGG; bme:BMEI0718; -.
DR PATRIC; fig|224914.52.peg.740; -.
DR eggNOG; COG2003; Bacteria.
DR OMA; AMPDYEL; -.
DR PhylomeDB; P65955; -.
DR Proteomes; UP000000419; Chromosome I.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0008237; F:metallopeptidase activity; IEA:UniProtKB-KW.
DR GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR CDD; cd08071; MPN_DUF2466; 1.
DR InterPro; IPR037518; MPN.
DR InterPro; IPR025657; RadC_JAB.
DR InterPro; IPR010994; RuvA_2-like.
DR InterPro; IPR001405; UPF0758.
DR InterPro; IPR020891; UPF0758_CS.
DR PANTHER; PTHR30471; PTHR30471; 1.
DR Pfam; PF04002; RadC; 1.
DR SUPFAM; SSF47781; SSF47781; 1.
DR TIGRFAMs; TIGR00608; radc; 1.
DR PROSITE; PS50249; MPN; 1.
DR PROSITE; PS01302; UPF0758; 1.
PE 3: Inferred from homology;
KW Hydrolase; Metal-binding; Metalloprotease; Protease; Zinc.
FT CHAIN 1..249
FT /note="UPF0758 protein BMEI0718"
FT /id="PRO_0000190688"
FT DOMAIN 127..249
FT /note="MPN"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU01182"
FT REGION 1..34
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT MOTIF 198..211
FT /note="JAMM motif"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU01182"
FT BINDING 198
FT /ligand="Zn(2+)"
FT /ligand_id="ChEBI:CHEBI:29105"
FT /ligand_note="catalytic"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU01182"
FT BINDING 200
FT /ligand="Zn(2+)"
FT /ligand_id="ChEBI:CHEBI:29105"
FT /ligand_note="catalytic"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU01182"
FT BINDING 211
FT /ligand="Zn(2+)"
FT /ligand_id="ChEBI:CHEBI:29105"
FT /ligand_note="catalytic"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU01182"
SQ SEQUENCE 249 AA; 27676 MW; 0DF77325A6F0638D CRC64;
MAKKKDTPGD GEFPGFSDTL QRTPKLEKPH YAGHRDRLKQ RFRDAPDALA DYELLELLLF
RAIRRADTKP IAKALLNRFG SIAEVLAAPE NLIAEIPGAG PTVALELKLV EAIAKRSARS
TVMEREVLGS WDKVINYCTA AMAFETREQF RILFLDKKNK LIADEVQQTG TVDHTPVYPR
EVVKRALELS ATAIILVHNH PSGDPTPSRA DIDMTKQLVN AAKALNITVH DHVIIGKHGH
ASLRSLRLI
