ID   Y730_STAA3              Reviewed;         356 AA.
AC   Q2FIP5;
DT   15-MAY-2007, integrated into UniProtKB/Swiss-Prot.
DT   21-MAR-2006, sequence version 1.
DT   25-MAY-2022, entry version 83.
DE   RecName: Full=Uncharacterized membrane protein SAUSA300_0730;
GN   OrderedLocusNames=SAUSA300_0730;
OS   Staphylococcus aureus (strain USA300).
OC   Bacteria; Firmicutes; Bacilli; Bacillales; Staphylococcaceae;
OC   Staphylococcus.
OX   NCBI_TaxID=367830;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=USA300;
RX   PubMed=16517273; DOI=10.1016/s0140-6736(06)68231-7;
RA   Diep B.A., Gill S.R., Chang R.F., Phan T.H., Chen J.H., Davidson M.G.,
RA   Lin F., Lin J., Carleton H.A., Mongodin E.F., Sensabaugh G.F.,
RA   Perdreau-Remington F.;
RT   "Complete genome sequence of USA300, an epidemic clone of community-
RT   acquired meticillin-resistant Staphylococcus aureus.";
RL   Lancet 367:731-739(2006).
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Multi-pass membrane
CC       protein {ECO:0000305}.
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DR   EMBL; CP000255; ABD22398.1; -; Genomic_DNA.
DR   RefSeq; WP_000460983.1; NZ_CP027476.1.
DR   AlphaFoldDB; Q2FIP5; -.
DR   SMR; Q2FIP5; -.
DR   EnsemblBacteria; ABD22398; ABD22398; SAUSA300_0730.
DR   KEGG; saa:SAUSA300_0730; -.
DR   HOGENOM; CLU_000445_11_1_9; -.
DR   OMA; HGAWKDL; -.
DR   Proteomes; UP000001939; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0000155; F:phosphorelay sensor kinase activity; IEA:InterPro.
DR   GO; GO:0071555; P:cell wall organization; IEA:InterPro.
DR   CDD; cd01949; GGDEF; 1.
DR   Gene3D; 3.30.70.270; -; 1.
DR   InterPro; IPR000160; GGDEF_dom.
DR   InterPro; IPR029787; Nucleotide_cyclase.
DR   InterPro; IPR043128; Rev_trsase/Diguanyl_cyclase.
DR   InterPro; IPR011620; Sig_transdc_His_kinase_LytS_TM.
DR   Pfam; PF07694; 5TM-5TMR_LYT; 1.
DR   Pfam; PF00990; GGDEF; 1.
DR   SMART; SM00267; GGDEF; 1.
DR   SUPFAM; SSF55073; SSF55073; 1.
DR   TIGRFAMs; TIGR00254; GGDEF; 1.
DR   PROSITE; PS50887; GGDEF; 1.
PE   4: Predicted;
KW   Cell membrane; Membrane; Transmembrane; Transmembrane helix.
FT   CHAIN           1..356
FT                   /note="Uncharacterized membrane protein SAUSA300_0730"
FT                   /id="PRO_0000286960"
FT   TRANSMEM        2..22
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        35..55
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        74..94
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        99..119
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        124..144
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        154..174
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   DOMAIN          218..353
FT                   /note="GGDEF"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00095"
SQ   SEQUENCE   356 AA;  40345 MW;  E687E1CD5FFA8989 CRC64;
     MFEAFIYNIS VIVAGIYLFH RLQYSENKRM VFSKAYVTVL MTIVSLLLSV YPIPYREDYL
     IHLTFVPLLF LGRFTNMVYT LSATVIVAIV EIVVFNNSIM YGVTLIVIAA VTSAIGPFLK
     QNDVLSLLIL NVVTIIILFG VALVSPIYTL SEVIILIPIS LIITLASAIT FVDIWHFFSL
     VNRYENEDKY DYLTGLGNVK EFDRHLNEIS RKAEKEHQSI ALLLIDIDGF KDVNDTYSHK
     SGDAVLKQMS QLLKNYVPNQ FKIFRNGGEE FSVVIHNYSL DQSVKLAENI RSGVEKSSFH
     LPNKEVIKLS VSIGVGYLTD DDPKSQRKVF KDADDMVHVA KNQGRNKVMF NPIINL