ID   Y733_CORDI              Reviewed;         987 AA.
AC   Q6NIN5;
DT   27-SEP-2005, integrated into UniProtKB/Swiss-Prot.
DT   05-JUL-2004, sequence version 1.
DT   03-AUG-2022, entry version 88.
DE   RecName: Full=UPF0182 protein DIP0733 {ECO:0000255|HAMAP-Rule:MF_01600};
GN   OrderedLocusNames=DIP0733;
OS   Corynebacterium diphtheriae (strain ATCC 700971 / NCTC 13129 / Biotype
OS   gravis).
OC   Bacteria; Actinobacteria; Corynebacteriales; Corynebacteriaceae;
OC   Corynebacterium.
OX   NCBI_TaxID=257309;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 700971 / NCTC 13129 / Biotype gravis;
RX   PubMed=14602910; DOI=10.1093/nar/gkg874;
RA   Cerdeno-Tarraga A.-M., Efstratiou A., Dover L.G., Holden M.T.G.,
RA   Pallen M.J., Bentley S.D., Besra G.S., Churcher C.M., James K.D.,
RA   De Zoysa A., Chillingworth T., Cronin A., Dowd L., Feltwell T., Hamlin N.,
RA   Holroyd S., Jagels K., Moule S., Quail M.A., Rabbinowitsch E.,
RA   Rutherford K.M., Thomson N.R., Unwin L., Whitehead S., Barrell B.G.,
RA   Parkhill J.;
RT   "The complete genome sequence and analysis of Corynebacterium diphtheriae
RT   NCTC13129.";
RL   Nucleic Acids Res. 31:6516-6523(2003).
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000255|HAMAP-Rule:MF_01600};
CC       Multi-pass membrane protein {ECO:0000255|HAMAP-Rule:MF_01600}.
CC   -!- SIMILARITY: Belongs to the UPF0182 family. {ECO:0000255|HAMAP-
CC       Rule:MF_01600}.
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DR   EMBL; BX248356; CAE49255.1; -; Genomic_DNA.
DR   RefSeq; WP_010934515.1; NC_002935.2.
DR   AlphaFoldDB; Q6NIN5; -.
DR   SMR; Q6NIN5; -.
DR   STRING; 257309.DIP0733; -.
DR   PRIDE; Q6NIN5; -.
DR   EnsemblBacteria; CAE49255; CAE49255; DIP0733.
DR   KEGG; cdi:DIP0733; -.
DR   HOGENOM; CLU_007733_1_0_11; -.
DR   OMA; HLRYPQD; -.
DR   OrthoDB; 170146at2; -.
DR   PHI-base; PHI:7592; -.
DR   PHI-base; PHI:8376; -.
DR   Proteomes; UP000002198; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   HAMAP; MF_01600; UPF0182; 1.
DR   InterPro; IPR005372; UPF0182.
DR   PANTHER; PTHR39344; PTHR39344; 1.
DR   Pfam; PF03699; UPF0182; 1.
PE   3: Inferred from homology;
KW   Cell membrane; Membrane; Reference proteome; Transmembrane;
KW   Transmembrane helix.
FT   CHAIN           1..987
FT                   /note="UPF0182 protein DIP0733"
FT                   /id="PRO_0000157716"
FT   TRANSMEM        19..39
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01600"
FT   TRANSMEM        63..83
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01600"
FT   TRANSMEM        115..135
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01600"
FT   TRANSMEM        176..196
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01600"
FT   TRANSMEM        212..234
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01600"
FT   TRANSMEM        261..281
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01600"
FT   TRANSMEM        290..310
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01600"
FT   REGION          904..950
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        904..927
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   987 AA;  108774 MW;  616D0687D0F239E5 CRC64;
     MATGFTRPAA APKRPQRRLT WLIPLLMILG ALVPTVVDLY TDWLWFGEVD FRGVFNKVIA
     TRIGLFVGFG LLAGIVTFLA GWFTYRGRPD ELEFFDPDSP VVQYRAAVEK GVHRFLVVLP
     VVIGIAAGFL GQQAWQTVQL FFNRQDFGVS DQQFGMDYGF YAFTLPALRL VVSTFSVLLV
     VAFLIALVGH YLLGGIRAGN QAAGVKGSIT NYAKVQLAVT GGLYLLVRMA SYWLDRYSLL
     NNSHETFTGG SYTDINAVLP AKIVLLVISA VVAISFFSVI VTKDLRIPAI STVLMIVSSL
     AIGNAWPIMM ERFSVSPNRA EKESEYISRN IEATRYAYGI TDDAVTYKDN WGAKGASSEK
     VASDSATVSN IRLLDPEIIS PTFTQQQQLR NFYGFPKSLA MDRYVIDGEL RDFVVAAREL
     DPNALKENQR DWINRHTVYT HGNGIVAAQA NQVDEVARDV GSARGGYPVY TVSDLQTTDK
     EAQELGIVVK EPRIYYGPVI ASATDGADYA VVGSENDSSV EYDTDSSTYT YQGKGGVNIG
     NVINRAAFAM RYQELNLILS DRVNGNSKIL YDRDPRERVH NVAPWLTTDS TTYPAVIDGR
     VKWIVDGYTT LTSLPYAERT SLSEATNDTT AQVGNSAQRL VTDNVGYIRN SVKAVVDSYD
     GSVDLYEFDE NDPVLKAWKG VFPGTVKAKS EISEELMNHL RYPEDMFKVQ RKMLARYHVD
     DARDFFTNDR FWSVPSDPSA TEGQKDVAQP AYYVVAADPD TGKPSFQLIT PFRGLQREYL
     AAHMSVSSDP DNYGKITVRV LPTDTLTQGP KQAQDTMMSS DQIASDRTLW KDTNDLFNGN
     LLTLPVGDGD ILYVEPLYSQ RKNQASAFPK LLRVLVSYQG KVGYAPTIAE ALSQVGIDPK
     EAQDLGEAKG LKPESQNRDK PEDKEGKAPS TPSAPASGSG TTGEAIGKIN DALNKLQSAK
     NGSNEEYGRA LDELDKAVEE YRKVAGQ