Y7407_DICDI
ID Y7407_DICDI Reviewed; 1663 AA.
AC Q54KD0;
DT 24-NOV-2009, integrated into UniProtKB/Swiss-Prot.
DT 24-MAY-2005, sequence version 1.
DT 25-MAY-2022, entry version 94.
DE RecName: Full=TPR repeat-containing protein DDB_G0287407;
GN ORFNames=DDB_G0287407;
OS Dictyostelium discoideum (Slime mold).
OC Eukaryota; Amoebozoa; Evosea; Eumycetozoa; Dictyostelia; Dictyosteliales;
OC Dictyosteliaceae; Dictyostelium.
OX NCBI_TaxID=44689;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=AX4;
RX PubMed=15875012; DOI=10.1038/nature03481;
RA Eichinger L., Pachebat J.A., Gloeckner G., Rajandream M.A., Sucgang R.,
RA Berriman M., Song J., Olsen R., Szafranski K., Xu Q., Tunggal B.,
RA Kummerfeld S., Madera M., Konfortov B.A., Rivero F., Bankier A.T.,
RA Lehmann R., Hamlin N., Davies R., Gaudet P., Fey P., Pilcher K., Chen G.,
RA Saunders D., Sodergren E.J., Davis P., Kerhornou A., Nie X., Hall N.,
RA Anjard C., Hemphill L., Bason N., Farbrother P., Desany B., Just E.,
RA Morio T., Rost R., Churcher C.M., Cooper J., Haydock S., van Driessche N.,
RA Cronin A., Goodhead I., Muzny D.M., Mourier T., Pain A., Lu M., Harper D.,
RA Lindsay R., Hauser H., James K.D., Quiles M., Madan Babu M., Saito T.,
RA Buchrieser C., Wardroper A., Felder M., Thangavelu M., Johnson D.,
RA Knights A., Loulseged H., Mungall K.L., Oliver K., Price C., Quail M.A.,
RA Urushihara H., Hernandez J., Rabbinowitsch E., Steffen D., Sanders M.,
RA Ma J., Kohara Y., Sharp S., Simmonds M.N., Spiegler S., Tivey A.,
RA Sugano S., White B., Walker D., Woodward J.R., Winckler T., Tanaka Y.,
RA Shaulsky G., Schleicher M., Weinstock G.M., Rosenthal A., Cox E.C.,
RA Chisholm R.L., Gibbs R.A., Loomis W.F., Platzer M., Kay R.R.,
RA Williams J.G., Dear P.H., Noegel A.A., Barrell B.G., Kuspa A.;
RT "The genome of the social amoeba Dictyostelium discoideum.";
RL Nature 435:43-57(2005).
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DR EMBL; AAFI02000100; EAL63771.1; -; Genomic_DNA.
DR RefSeq; XP_637293.1; XM_632201.1.
DR AlphaFoldDB; Q54KD0; -.
DR SMR; Q54KD0; -.
DR STRING; 44689.DDB0232091; -.
DR PaxDb; Q54KD0; -.
DR EnsemblProtists; EAL63771; EAL63771; DDB_G0287407.
DR GeneID; 8626125; -.
DR KEGG; ddi:DDB_G0287407; -.
DR dictyBase; DDB_G0287407; -.
DR eggNOG; KOG1840; Eukaryota.
DR eggNOG; KOG3602; Eukaryota.
DR HOGENOM; CLU_242088_0_0_1; -.
DR InParanoid; Q54KD0; -.
DR OMA; MNICESK; -.
DR PhylomeDB; Q54KD0; -.
DR PRO; PR:Q54KD0; -.
DR Proteomes; UP000002195; Chromosome 5.
DR Gene3D; 1.25.40.10; -; 2.
DR Gene3D; 3.40.50.300; -; 1.
DR InterPro; IPR025139; DUF4062.
DR InterPro; IPR014756; Ig_E-set.
DR InterPro; IPR007111; NACHT_NTPase.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR011990; TPR-like_helical_dom_sf.
DR InterPro; IPR019734; TPR_repeat.
DR Pfam; PF13271; DUF4062; 1.
DR Pfam; PF05729; NACHT; 1.
DR SMART; SM00028; TPR; 5.
DR SUPFAM; SSF48452; SSF48452; 2.
DR SUPFAM; SSF52540; SSF52540; 1.
DR SUPFAM; SSF81296; SSF81296; 1.
DR PROSITE; PS50293; TPR_REGION; 1.
PE 4: Predicted;
KW Coiled coil; Reference proteome; Repeat; TPR repeat.
FT CHAIN 1..1663
FT /note="TPR repeat-containing protein DDB_G0287407"
FT /id="PRO_0000389243"
FT REPEAT 1110..1143
FT /note="TPR 1"
FT REPEAT 1150..1183
FT /note="TPR 2"
FT REPEAT 1192..1225
FT /note="TPR 3"
FT REPEAT 1234..1269
FT /note="TPR 4"
FT REPEAT 1278..1311
FT /note="TPR 5"
FT REPEAT 1320..1353
FT /note="TPR 6"
FT REGION 84..109
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 326..359
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1500..1528
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1544..1571
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 1516..1547
FT /evidence="ECO:0000255"
FT COMPBIAS 85..109
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 334..352
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1663 AA; 188148 MW; 9986AD34C3E6DE07 CRC64;
MKNIFKDKNI YILSVENDQR DKCKSYLISK KALVEKRFSK KVNIIITSEK TILENKFPVN
TATKLGIEII DYETLSRDIE RFIRKTQPTS SNGSTSTTTT TTTTTQKGQI VSFKPTSSTS
TTTNVINTTT TSTTSTTTIV DPIISLIVPP SGSNNGSFQI AIFGIGFLAG AGFRIKIGND
NGGGGVFASN YEFHSSTSVL CTIPNLNIKC GQQPIYASND GGKTFGFPIQ FLFFDTSIHR
IPTAREQDGM VLKSQLDNLK RAISNIQTME SILMRRISLL NGNHDDSKSI EQIFIQQQNF
IESGASQLLL GNGGTTDQLL QSLEGSEYSS TNDDGENDQS DDDDDNEDDD DFVEKNSNQV
KEEFSEREIK IFISSPFKDM QLDRDQIVKV VIPRIRKLCI ERDIVLSYVD LRWGVTSNQS
EQSTGLSMCL KELEKCNILI GLFGERYGWS SQEKQDPKSQ QLLQSTLDRA IQDFPWVKNY
RDSSITEIEF RMLLNQRQQQ RNGFFYFRDP YYLEEVSQMD KNNFVSEGQR SKEKLEKLKQ
EIIKSPFKSS EYRRPTNLSD VLYEDLEKYI DKKYPSGNCE LKGFEKERFL HSVFIKNLTK
IYITNENYFM EIDTYLSGSA TSSGSGNKSI SIGSSINSGL LSSLKNKPVF LIQGESGSGK
SSLISNWLKQ HKEQHPEDLV VSHWIGASPS SNKFTSILIR IMNEIKNQIE IDQKIANGGS
NSSSSSSSSM FSTTSTSSVS WLPEIPDETF ESEKIVSEFP QFLQYVMSHP SLNGKRLVLL
IDGLDKLDPR ENSQELIWFP RNFPHNVKVI VSSIQGSRQS EVLKKRGSHI LSILPFTEAE
RKSMVRLYLQ KYAKKLSDQQ EIAIAISKST TNPRFLQLLL DDILVFGDYE RLNDRIKTLL
RAKNTSELYE IILDRIEKDY DPKAKGLVSE FLKYIWAGRR GVEMSMLSTL LLKKNIDPAE
WGSLLVLMEA YITSSSGVIS FLNDDISKAV EKKYITTPKI GIEIHTNLAE AFEQSGDLNE
RKVEEYPYQL LKSENWESLK NTLTNLYVFD KLYTPNHKVD LINYWNVLEK QTKPPKNAAE
RDDPIPYNCS NEFKAIISRS FIQASGLVIS DVWFRVASFL EELSQFDGAE VLYNKCRELY
INNSQNIEAA KVDRAMGRMY LTMGQNDKSD SKFRLALSIY TKERGQEDIE VAITLNLLGT
LATNRCKFDE AKQILNQAMN ICESKYESNV LLIADIAYSL GSVCFVEPNR KLEVAEAYFA
RSLELTESKV GDMDVAYARI LTRLGSLNIE KDTYADAEAF FKAALKIYEA RLGIDHSRVS
QILRHMISLY EVQENYKMAE QCCIRALAIT KKIYGNSHNL VSATQIRQAL LYNSMNRKQD
CLNLLNEVKV TREKEFGPDH KQVKHIIDLI KEIDKPIVPK APPPPPPSSS SPSASSLLMK
SITSLPIVNG QAVLSVPKPP VSRGPNGIPI PPPPPPTIKL YTNMVSLQSV MKQNVGRIPV
AQPTSFNSPV QPPSPRTQQA IQQGQQQRQQ VQQQQQQVQQ QMSQKVSSLQ QQPQQQQQQQ
PSQGYGNRQN TPLFQQPIFQ QQFQQNRIQQ PQQQPQQQAY VGDMLAQFDQ QKLKRVQNAN
DRSGASQIVE NLIGKKKCSK PVSLVNKGYM EESNQIDMGA LFD
